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Protein
Submitted name:

G protein-coupled receptor 55, isoform CRA_a

Gene

GPR55

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
G protein-coupled receptor 55, isoform CRA_aImported
Submitted name:
cDNA FLJ75410, highly similar to Homo sapiens G protein-coupled receptor 55, mRNAImported
Gene namesi
Name:GPR55Imported
ORF Names:hCG_1645175Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000135898.9

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei24 – 49HelicalSequence analysisAdd BLAST26
Transmembranei61 – 79HelicalSequence analysisAdd BLAST19
Transmembranei99 – 117HelicalSequence analysisAdd BLAST19
Transmembranei138 – 161HelicalSequence analysisAdd BLAST24
Transmembranei181 – 202HelicalSequence analysisAdd BLAST22
Transmembranei223 – 248HelicalSequence analysisAdd BLAST26
Transmembranei268 – 291HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA28900

Expressioni

Gene expression databases

BgeeiENSG00000135898
ExpressionAtlasiA8K858 baseline and differential

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini37 – 288G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST252

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IEJJ Eukaryota
ENOG4111H9D LUCA
HOVERGENiHBG096388
KOiK08413
OMAiCFHNMSD
OrthoDBiEOG091G0CP3

Family and domain databases

InterProiView protein in InterPro
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
IPR028334 GPR55
PANTHERiPTHR24232:SF56 PTHR24232:SF56, 1 hit
PfamiView protein in Pfam
PF00001 7tm_1, 1 hit
PRINTSiPR00237 GPCRRHODOPSN
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequencei

Sequence statusi: Complete.

A8K858-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQQNTSGDC LFDGVNELMK TLQFAVHIPT FVLGLLLNLL AIHGFSTFLK
60 70 80 90 100
NRWPDYAATS IYMINLAVFD LLLVLSLPFK MVLSQVQSPF PSLCTLVECL
110 120 130 140 150
YFVSMYGSVF TICFISMDRF LAIRYPLLVS HLRSPRKIFG ICCTIWVLVW
160 170 180 190 200
TGSIPIYSFH GKVEKYMCFH NMSDDTWSAK VFFPLEVFGF LLPMGIMGFC
210 220 230 240 250
CSRSIHILLG RRDHTQDWVQ QKACIYSIAA SLAVFVVSFL PVHLGFFLQF
260 270 280 290 300
LVRNSFIVEC RAKQSISFFL QLSMCFSNVN CCLDVFCYYF VIKEFRMNIR
310
AHRPSRVQLV LQDTTISRG
Length:319
Mass (Da):36,637
Last modified:December 4, 2007 - v1
Checksum:iD6E5C6CA8426E7D5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FJ348259 mRNA Translation: ACI96303.1
AK292223 mRNA Translation: BAF84912.1
CH471063 Genomic DNA Translation: EAW70939.1
CH471063 Genomic DNA Translation: EAW70940.1
RefSeqiNP_005674.2, NM_005683.3
XP_005247009.1, XM_005246952.3
XP_011510477.1, XM_011512175.2
XP_011510478.1, XM_011512176.2
UniGeneiHs.114545

Genome annotation databases

GeneIDi9290
KEGGihsa:9290

Similar proteinsi

Entry informationi

Entry nameiA8K858_HUMAN
AccessioniPrimary (citable) accession number: A8K858
Entry historyiIntegrated into UniProtKB/TrEMBL: December 4, 2007
Last sequence update: December 4, 2007
Last modified: June 20, 2018
This is version 90 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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