Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Myelin protein zero-like 1, isoform CRA_b

Gene

MPZL1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Myelin protein zero-like 1, isoform CRA_bImported
Submitted name:
cDNA FLJ78597, highly similar to Homo sapiens myelin protein zero-like 1 (MPZL1), transcript variant 1, mRNAImported
Submitted name:
cDNA, FLJ96614, Homo sapiens myelin protein zero-like 1 (MPZL1), mRNAImported
Gene namesi
Name:MPZL1Imported
ORF Names:hCG_42390Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000197965.11

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei165 – 191HelicalSequence analysisAdd BLAST27

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA30931

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 37Sequence analysisAdd BLAST37
ChainiPRO_501429754038 – 269Sequence analysisAdd BLAST232

Expressioni

Gene expression databases

BgeeiENSG00000197965 Expressed in 219 organ(s), highest expression level in urinary bladder

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini36 – 146Ig-likeInterPro annotationAdd BLAST111

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IVXC Eukaryota
ENOG4111MDZ LUCA
HOVERGENiHBG104511
KOiK06770
OMAiPGNYPPF
OrthoDBiEOG091G0H91

Family and domain databases

Gene3Di2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR003599 Ig_sub
IPR013106 Ig_V-set
IPR029870 MPZL1
IPR000920 Myelin_P0-rel
PANTHERiPTHR13869 PTHR13869, 1 hit
PTHR13869:SF19 PTHR13869:SF19, 1 hit
PfamiView protein in Pfam
PF07686 V-set, 1 hit
PRINTSiPR00213 MYELINP0
SMARTiView protein in SMART
SM00409 IG, 1 hit
SM00406 IGv, 1 hit
SUPFAMiSSF48726 SSF48726, 1 hit
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 1 hit

Sequencei

Sequence statusi: Complete.

A8K5D4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAASAGAGAV IAAPDSRRWL WSVLAAALGL LTAGVSALEV YTPKEIFVAN
60 70 80 90 100
GTQGKLTCKF KSTSTTGGLT SVSWSFQPEG ADTTVSFFHY SQGQVYLGNY
110 120 130 140 150
PPFKDRISWA GDLDKKDASI NIENMQFIHN GTYICDVKNP PDIVVQPGHI
160 170 180 190 200
RLYVVEKENL PVFPVWVVVG IVTAVVLGLT LLISMILAVL YRRKNSKRDY
210 220 230 240 250
TGCSTSESLS PVKQAPRKSP SDTEGLVKSL PSGSHQGPVI YAQLDHSGGH
260
HSDKINKSES VVYADIRKN
Length:269
Mass (Da):29,082
Last modified:December 4, 2007 - v1
Checksum:iA1B299041EE59425
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK291249 mRNA Translation: BAF83938.1
AK315546 mRNA Translation: BAG37924.1
CH471067 Genomic DNA Translation: EAW90801.1
CH471067 Genomic DNA Translation: EAW90803.1
RefSeqiNP_003944.1, NM_003953.5
UniGeneiHs.493919

Genome annotation databases

GeneIDi9019
KEGGihsa:9019

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK291249 mRNA Translation: BAF83938.1
AK315546 mRNA Translation: BAG37924.1
CH471067 Genomic DNA Translation: EAW90801.1
CH471067 Genomic DNA Translation: EAW90803.1
RefSeqiNP_003944.1, NM_003953.5
UniGeneiHs.493919

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

DNASUi9019
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi9019
KEGGihsa:9019

Organism-specific databases

CTDi9019
EuPathDBiHostDB:ENSG00000197965.11
PharmGKBiPA30931

Phylogenomic databases

eggNOGiENOG410IVXC Eukaryota
ENOG4111MDZ LUCA
HOVERGENiHBG104511
KOiK06770
OMAiPGNYPPF
OrthoDBiEOG091G0H91

Miscellaneous databases

ChiTaRSiMPZL1 human
GenomeRNAii9019

Gene expression databases

BgeeiENSG00000197965 Expressed in 219 organ(s), highest expression level in urinary bladder

Family and domain databases

Gene3Di2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR003599 Ig_sub
IPR013106 Ig_V-set
IPR029870 MPZL1
IPR000920 Myelin_P0-rel
PANTHERiPTHR13869 PTHR13869, 1 hit
PTHR13869:SF19 PTHR13869:SF19, 1 hit
PfamiView protein in Pfam
PF07686 V-set, 1 hit
PRINTSiPR00213 MYELINP0
SMARTiView protein in SMART
SM00409 IG, 1 hit
SM00406 IGv, 1 hit
SUPFAMiSSF48726 SSF48726, 1 hit
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA8K5D4_HUMAN
AccessioniPrimary (citable) accession number: A8K5D4
Entry historyiIntegrated into UniProtKB/TrEMBL: December 4, 2007
Last sequence update: December 4, 2007
Last modified: November 7, 2018
This is version 98 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again