UniProtKB - A8K287 (A8K287_HUMAN)
Protein
Synaptosomal-associated protein
Gene
SNAP23
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Recommended name: Synaptosomal-associated proteinUniRule annotation |
Gene namesi | Name:SNAP23Imported ORF Names:hCG_40424Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Organism-specific databases
VEuPathDBi | HostDB:ENSG00000092531.9 |
Subcellular locationi
Plasma membrane
- Cell membrane ARBA annotation; Lipid-anchor ARBA annotation
Other locations
- synaptosome ARBA annotation
- Membrane ARBA annotation; Lipid-anchor ARBA annotation
Nucleus
- nucleoplasm Source: HPA
Plasma Membrane
- plasma membrane Source: HPA
Other locations
- neuron projection Source: UniProtKB-KW
- synapse Source: UniProtKB-SubCell
Keywords - Cellular componenti
Cell junction, Synapse, SynaptosomeARBA annotationPTM / Processingi
Keywords - PTMi
Lipoprotein, PalmitateARBA annotationProteomic databases
PRIDEi | A8K287 |
Expressioni
Gene expression databases
Bgeei | ENSG00000092531, Expressed in chorionic villus and 243 other tissues |
ExpressionAtlasi | A8K287, baseline and differential |
Interactioni
Binary interactionsi
Hide detailsA8K287
With | #Exp. | IntAct |
---|---|---|
NAPB [Q9H115] | 3 | EBI-10188497,EBI-3921185 |
STX11 [O75558] | 3 | EBI-10188497,EBI-714135 |
VAMP5 [O95183] | 3 | EBI-10188497,EBI-10191195 |
Protein-protein interaction databases
IntActi | A8K287, 3 interactors |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 14 – 76 | T-SNARE coiled-coil homologyInterPro annotationAdd BLAST | 63 | |
Domaini | 146 – 208 | T-SNARE coiled-coil homologyInterPro annotationAdd BLAST | 63 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 20 | DisorderedSequence analysisAdd BLAST | 20 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 45 – 79 | Sequence analysisAdd BLAST | 35 |
Sequence similaritiesi
Keywords - Domaini
Coiled coilPROSITE-ProRule annotationARBA annotation, RepeatARBA annotationPhylogenomic databases
OMAi | QINRTHV |
OrthoDBi | 1358184at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR000928, SNAP-25_dom IPR000727, T_SNARE_dom |
Pfami | View protein in Pfam PF00835, SNAP-25, 1 hit |
SMARTi | View protein in SMART SM00397, t_SNARE, 2 hits |
PROSITEi | View protein in PROSITE PS50192, T_SNARE, 2 hits |
i Sequence
Sequence statusi: Complete.
A8K287-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDNLSSEEIQ QRAHQITDES LESTRRILGL AIESQDAGIK TITMLDEQKE
60 70 80 90 100
QLNRIEEGLD QINKDMRETE KTLTELNKCC GLCVCPCNRT KNFESGKAYK
110 120 130 140 150
TTWGDGGENS PCNVVSKQPG PVTNGQLQQP TTGAASGGYI KRITNDARED
160 170 180 190 200
EMEENLTQVG SILGNLKDMA LNIGNEIDAQ NPQIKRITDK ADTNRDRIDI
210
ANARAKKLID S
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK290152 mRNA Translation: BAF82841.1 AK313161 mRNA Translation: BAG35979.1 CH471125 Genomic DNA Translation: EAW92556.1 CH471125 Genomic DNA Translation: EAW92558.1 |
RefSeqi | NP_003816.2, NM_003825.3 NP_570710.1, NM_130798.2 |
Genome annotation databases
GeneIDi | 8773 |
KEGGi | hsa:8773 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK290152 mRNA Translation: BAF82841.1 AK313161 mRNA Translation: BAG35979.1 CH471125 Genomic DNA Translation: EAW92556.1 CH471125 Genomic DNA Translation: EAW92558.1 |
RefSeqi | NP_003816.2, NM_003825.3 NP_570710.1, NM_130798.2 |
3D structure databases
SMRi | A8K287 |
ModBasei | Search... |
Protein-protein interaction databases
IntActi | A8K287, 3 interactors |
Proteomic databases
PRIDEi | A8K287 |
Protocols and materials databases
Antibodypediai | 712, 421 antibodies |
DNASUi | 8773 |
Genome annotation databases
GeneIDi | 8773 |
KEGGi | hsa:8773 |
Organism-specific databases
CTDi | 8773 |
PharmGKBi | PA35979 |
VEuPathDBi | HostDB:ENSG00000092531.9 |
Phylogenomic databases
OMAi | QINRTHV |
OrthoDBi | 1358184at2759 |
Miscellaneous databases
BioGRID-ORCSi | 8773, 413 hits in 1003 CRISPR screens |
ChiTaRSi | SNAP23, human |
GenomeRNAii | 8773 |
Gene expression databases
Bgeei | ENSG00000092531, Expressed in chorionic villus and 243 other tissues |
ExpressionAtlasi | A8K287, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR000928, SNAP-25_dom IPR000727, T_SNARE_dom |
Pfami | View protein in Pfam PF00835, SNAP-25, 1 hit |
SMARTi | View protein in SMART SM00397, t_SNARE, 2 hits |
PROSITEi | View protein in PROSITE PS50192, T_SNARE, 2 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A8K287_HUMAN | |
Accessioni | A8K287Primary (citable) accession number: A8K287 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | December 4, 2007 |
Last sequence update: | December 4, 2007 | |
Last modified: | April 7, 2021 | |
This is version 116 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |