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Entry version 95 (13 Feb 2019)
Sequence version 1 (04 Dec 2007)
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Protein

Zinc finger protein 839

Gene

ZNF839

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri197 – 222C2H2-typePROSITE-ProRule annotationAdd BLAST26

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandMetal-binding, Zinc

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-212436 Generic Transcription Pathway

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 839
Alternative name(s):
Renal carcinoma antigen NY-REN-50
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF839
Synonyms:C14orf131
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 14

Organism-specific databases

Eukaryotic Pathogen Database Resources

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EuPathDBi
HostDB:ENSG00000022976.15

Human Gene Nomenclature Database

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HGNCi
HGNC:20345 ZNF839

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_A8K0R7

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000022976

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162410800

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ZNF839

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003287211 – 811Zinc finger protein 839Add BLAST811

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
A8K0R7

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
A8K0R7

MaxQB - The MaxQuant DataBase

More...
MaxQBi
A8K0R7

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
A8K0R7

PRoteomics IDEntifications database

More...
PRIDEi
A8K0R7

ProteomicsDB human proteome resource

More...
ProteomicsDBi
1838
1839 [A8K0R7-2]
1840 [A8K0R7-5]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
A8K0R7

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
A8K0R7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

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Bgeei
ENSG00000022976 Expressed in 206 organ(s), highest expression level in testis

ExpressionAtlas, Differential and Baseline Expression

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ExpressionAtlasi
A8K0R7 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
A8K0R7 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA020434

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
120893, 5 interactors

Protein interaction database and analysis system

More...
IntActi
A8K0R7, 2 interactors

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
A8K0R7

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
A8K0R7

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi103 – 108Poly-Ser6

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri197 – 222C2H2-typePROSITE-ProRule annotationAdd BLAST26

Keywords - Domaini

Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
ENOG410IFJC Eukaryota
ENOG4111JK5 LUCA

Ensembl GeneTree

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GeneTreei
ENSGT00390000002751

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG108776

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
A8K0R7

Identification of Orthologs from Complete Genome Data

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OMAi
PGHGQLE

Database of Orthologous Groups

More...
OrthoDBi
861724at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
A8K0R7

TreeFam database of animal gene trees

More...
TreeFami
TF328610

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR031885 DUF4764
IPR039946 ZN839
IPR013087 Znf_C2H2_type

The PANTHER Classification System

More...
PANTHERi
PTHR16116 PTHR16116, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF15961 DUF4764, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50157 ZINC_FINGER_C2H2_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 7 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: A8K0R7-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MLLPTTIQPQ TARKSQLPRG NSCLVGLHIA SPQLLRVQPL VRTEPQSCFL
60 70 80 90 100
SDLCQPPAQG FVQRPLPALQ VVPAKRVPAP KAPDEQGSML TPLSASDPLA
110 120 130 140 150
VTSLSSSSAH PFISNLHTRH TEKLKKSLKV KTRSGRVSRP PKYKAKDYKF
160 170 180 190 200
IKTEDLADGH LSDSDDYSEL CVEEDEDQRE RHALFDLSSC SLRPKSFKCQ
210 220 230 240 250
TCEKSYIGKG GLARHFKLNP GHGQLDPEMV LSEKASGSTL RGCTEERTLS
260 270 280 290 300
LTSLGLSMPA DPCEGGARSC LVTESARGGL QNGQSVDVEE TLPSEPENGA
310 320 330 340 350
LLRSERYQGP RRRACSETLA ESRTAVLQQR RAAQLPGGPA AAGEQRASPS
360 370 380 390 400
KARLKEFLQQ CDREDLVELA LPQLAQVVTV YEFLLMKVEK DHLAKPFFPA
410 420 430 440 450
IYKEFEELHK MVKKMCQDYL SSSGLCSQET LEINNDKVAE SLGITEFLRK
460 470 480 490 500
KEIHPDNLGP KHLSRDMDGE QLEGASSEKR EREAAEEGLA SVKRPRREAL
510 520 530 540 550
SNDTTESLAA NSRGREKPRP LHALAAGFSP PVNVTVSPRS EESHTTTVSG
560 570 580 590 600
GNGSVFQAGP QLQALANLEA RRGSIGAALS SRDVSGLPVY AQSGEPRRLT
610 620 630 640 650
QAQVAAFPGE NALEHSSDQD TWDSLRSPGF CSPLSSGGGA ESLPPGGPGH
660 670 680 690 700
AEAGHLGKVC DFHLNHQQPS PTSVLPTEVA APPLEKILSV DSVAVDCAYR
710 720 730 740 750
TVPKPGPQPG PHGSLLTEGC LRSLSGDLNR FPCGMEVHSG QRELESVVAV
760 770 780 790 800
GEAMAFEISN GSHELLSQGQ KQIFIQTSDG LILSPPGTIV SQEEDIVTVT
810
DAEGRACGWA R
Length:811
Mass (Da):87,484
Last modified:December 4, 2007 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i58E2C46E98154976
GO
Isoform 2 (identifier: A8K0R7-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     527-527: G → GEG

Note: No experimental confirmation available.
Show »
Length:813
Mass (Da):87,670
Checksum:iADE65A604CA4AC52
GO
Isoform 3 (identifier: A8K0R7-5) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-1: M → MADAEPEAGG...GETKGQERPM

Note: No experimental confirmation available.
Show »
Length:927
Mass (Da):99,444
Checksum:iEDEACFA77ADFE155
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H0YM94H0YM94_HUMAN
Zinc finger protein 839
ZNF839
493Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YLB6H0YLB6_HUMAN
Zinc finger protein 839
ZNF839
475Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YM06H0YM06_HUMAN
Zinc finger protein 839
ZNF839
527Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YNU6H0YNU6_HUMAN
Zinc finger protein 839
ZNF839
190Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YKI3H0YKI3_HUMAN
Zinc finger protein 839
ZNF839
247Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YMU1H0YMU1_HUMAN
Zinc finger protein 839
ZNF839
144Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YKY1H0YKY1_HUMAN
Zinc finger protein 839
ZNF839
57Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAA92026 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence CAD62594 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti411M → L in AAH73137 (PubMed:15489334).Curated1
Sequence conflicti418D → G in BAD97032 (Ref. 5) Curated1
Sequence conflicti479K → E in BAG52694 (PubMed:14702039).Curated1
Sequence conflicti590Y → C in BAA92026 (PubMed:14702039).Curated1
Sequence conflicti771K → R in BAD97032 (Ref. 5) Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_057456314A → T. Corresponds to variant dbSNP:rs1543540Ensembl.1
Natural variantiVAR_042468531P → S. Corresponds to variant dbSNP:rs9464Ensembl.1
Natural variantiVAR_042469693V → M. Corresponds to variant dbSNP:rs28646161Ensembl.1
Natural variantiVAR_042470731F → L. Corresponds to variant dbSNP:rs1053019Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0406481M → MADAEPEAGGGSEDGGGGGG PAPPGQSGSVARVAPLGPEQ LRQVLEQVTKAQPPPPPPPF VLRDAARRLRDAAQQAALQR GRGTEPPRLPRLLPPQQLEA ICVKVTSGETKGQERPM in isoform 3. 1 Publication1
Alternative sequenceiVSP_032760527G → GEG in isoform 2. 1 Publication1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK001994 mRNA Translation: BAA92026.1 Different initiation.
AK289632 mRNA Translation: BAF82321.1
AK093342 mRNA Translation: BAG52694.1
AL137229 Genomic DNA No translation available.
AL352978 Genomic DNA No translation available.
BX248266 mRNA Translation: CAD62594.1 Different initiation.
BC073137 mRNA Translation: AAH73137.2
AK223312 mRNA Translation: BAD97032.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS45164.1 [A8K0R7-5]
CCDS58336.1 [A8K0R7-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001254756.1, NM_001267827.1 [A8K0R7-1]
NP_001254757.1, NM_001267828.1 [A8K0R7-1]
NP_060805.3, NM_018335.4 [A8K0R7-5]
XP_011535250.1, XM_011536948.2 [A8K0R7-1]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.743359

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000442396; ENSP00000399863; ENSG00000022976 [A8K0R7-5]
ENST00000558850; ENSP00000453363; ENSG00000022976 [A8K0R7-1]
ENST00000559185; ENSP00000453109; ENSG00000022976 [A8K0R7-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
55778

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:55778

UCSC genome browser

More...
UCSCi
uc001ylo.4 human [A8K0R7-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK001994 mRNA Translation: BAA92026.1 Different initiation.
AK289632 mRNA Translation: BAF82321.1
AK093342 mRNA Translation: BAG52694.1
AL137229 Genomic DNA No translation available.
AL352978 Genomic DNA No translation available.
BX248266 mRNA Translation: CAD62594.1 Different initiation.
BC073137 mRNA Translation: AAH73137.2
AK223312 mRNA Translation: BAD97032.1
CCDSiCCDS45164.1 [A8K0R7-5]
CCDS58336.1 [A8K0R7-1]
RefSeqiNP_001254756.1, NM_001267827.1 [A8K0R7-1]
NP_001254757.1, NM_001267828.1 [A8K0R7-1]
NP_060805.3, NM_018335.4 [A8K0R7-5]
XP_011535250.1, XM_011536948.2 [A8K0R7-1]
UniGeneiHs.743359

3D structure databases

ProteinModelPortaliA8K0R7
SMRiA8K0R7
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi120893, 5 interactors
IntActiA8K0R7, 2 interactors

PTM databases

iPTMnetiA8K0R7
PhosphoSitePlusiA8K0R7

Polymorphism and mutation databases

BioMutaiZNF839

Proteomic databases

EPDiA8K0R7
jPOSTiA8K0R7
MaxQBiA8K0R7
PaxDbiA8K0R7
PRIDEiA8K0R7
ProteomicsDBi1838
1839 [A8K0R7-2]
1840 [A8K0R7-5]

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000442396; ENSP00000399863; ENSG00000022976 [A8K0R7-5]
ENST00000558850; ENSP00000453363; ENSG00000022976 [A8K0R7-1]
ENST00000559185; ENSP00000453109; ENSG00000022976 [A8K0R7-1]
GeneIDi55778
KEGGihsa:55778
UCSCiuc001ylo.4 human [A8K0R7-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
55778
EuPathDBiHostDB:ENSG00000022976.15

GeneCards: human genes, protein and diseases

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GeneCardsi
ZNF839
HGNCiHGNC:20345 ZNF839
HPAiHPA020434
neXtProtiNX_A8K0R7
OpenTargetsiENSG00000022976
PharmGKBiPA162410800

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiENOG410IFJC Eukaryota
ENOG4111JK5 LUCA
GeneTreeiENSGT00390000002751
HOVERGENiHBG108776
InParanoidiA8K0R7
OMAiPGHGQLE
OrthoDBi861724at2759
PhylomeDBiA8K0R7
TreeFamiTF328610

Enzyme and pathway databases

ReactomeiR-HSA-212436 Generic Transcription Pathway

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
55778

Protein Ontology

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PROi
PR:A8K0R7

Gene expression databases

BgeeiENSG00000022976 Expressed in 206 organ(s), highest expression level in testis
ExpressionAtlasiA8K0R7 baseline and differential
GenevisibleiA8K0R7 HS

Family and domain databases

InterProiView protein in InterPro
IPR031885 DUF4764
IPR039946 ZN839
IPR013087 Znf_C2H2_type
PANTHERiPTHR16116 PTHR16116, 1 hit
PfamiView protein in Pfam
PF15961 DUF4764, 1 hit
PROSITEiView protein in PROSITE
PS50157 ZINC_FINGER_C2H2_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZN839_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A8K0R7
Secondary accession number(s): B3KSD2
, Q53FH5, Q6GPI5, Q86TU1, Q9BQ86, Q9NUU3
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 8, 2008
Last sequence update: December 4, 2007
Last modified: February 13, 2019
This is version 95 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 14
    Human chromosome 14: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
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