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Entry version 117 (02 Jun 2021)
Sequence version 1 (04 Dec 2007)
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Protein
Submitted name:

Scalloped, isoform D

Gene

sd

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position and type of each DNA-binding domain present within the protein.<p><a href='/help/dna_bind' target='_top'>More...</a></p>DNA bindingi61 – 137TEAPROSITE-ProRule annotationAdd BLAST77

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-bindingUniRule annotationARBA annotation
Biological processTranscription, Transcription regulationUniRule annotationARBA annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Scalloped, isoform DImported
Submitted name:
Scalloped, isoform JImported
Submitted name:
Scalloped, isoform OImported
Submitted name:
Scalloped, isoform PImported
Submitted name:
Scalloped, isoform UImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:sdImported
Synonyms:anon-EST:Liang-2.14Imported, clone 2.14Imported, Dmel\CG8544Imported, DROEXOImported, DROEXO2Imported, EP(X)1088Imported, EP1088Imported, l(1)G0239Imported, l(1)G0262Imported, l(1)G0309Imported, l(1)G0315Imported, l(1)G0483Imported, l(1)HF394Imported, l(1)IIIImported, SDImported, SdImported, spImported, TEADImported
ORF Names:CG8544Imported, Dmel_CG8544Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0003345, sd

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

NucleusUniRule annotationARBA annotation

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0003345, Expressed in eye disc (Drosophila) and 59 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
A8JUY5, baseline and differential

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
A8JUY5

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini61 – 137TEAInterPro annotationAdd BLAST77

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni20 – 40DisorderedSequence analysisAdd BLAST21

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000182956

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_012515_1_0_1

Database of Orthologous Groups

More...
OrthoDBi
823827at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.10.1610, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000818, TEA/ATTS_dom
IPR038096, TEA/ATTS_sf
IPR016361, TEF_metazoa
IPR041086, YBD

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01285, TEA, 1 hit
PF17725, YBD, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF002603, TEF, 2 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00065, TEADOMAIN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00426, TEA, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00554, TEA_1, 1 hit
PS51088, TEA_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All

A8JUY5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDCDYSKFLY KIGPGTIPSP WTPVNAGPPG ALGSADTNGS MVDSKNLDVG
60 70 80 90 100
DMSDDEKDLS SADAEGVWSP DIEQSFQEAL SIYPPCGRRK IILSDEGKMY
110 120 130 140 150
GRNELIARYI KLRTGKTRTR KQVSSHIQVL ARRKLREIQA KIKVQFWQPG
160 170 180 190 200
LQPSTSQDIK PFPQPPYPAG KTSTAVSGDE TGIPPSQLPW EGRAIATHKF
210 220 230 240 250
RLLEFTAFME IQRDEIYHRH LFVQLGGKPS FSDPLLETVD IRQIFDKFPE
260 270 280 290 300
KSGGLKDLYE KGPQNAFYLV KCWADLNTDL TTGSETGDFY GVTSQYESNE
310 320 330 340 350
NVVLVCSTIV CSFGKQVVEK VESEYSRLEN NRYVYRIQRS PMCEYMINFI
360 370 380 390 400
QKLKNLPERY MMNSVLENFT ILQVMRARET QETLLCIAYV FEVAAQNSGT
410
THHIYRLIKE
Length:410
Mass (Da):46,522
Last modified:December 4, 2007 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iBFFA93F29ACFF590
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P30052SCAL_DROME
Protein scalloped
sd CG8544
440Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q8IR25Q8IR25_DROME
Scalloped, isoform A
sd anon-EST:Liang-2.14, clone 2.14, Dmel\CG8544, DROEXO, DROEXO2
370Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
X2JFL9X2JFL9_DROME
Scalloped, isoform T
sd anon-EST:Liang-2.14, clone 2.14, Dmel\CG8544, DROEXO, DROEXO2
375Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E1JJ99E1JJ99_DROME
FI18101p1
sd anon-EST:Liang-2.14, clone 2.14, Dmel\CG8544, DROEXO, DROEXO2
435Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A8JUY9A8JUY9_DROME
Scalloped, isoform E
sd anon-EST:Liang-2.14, clone 2.14, Dmel\CG8544, DROEXO, DROEXO2
440Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M9PH78M9PH78_DROME
Scalloped, isoform Q
sd anon-EST:Liang-2.14, clone 2.14, Dmel\CG8544, DROEXO, DROEXO2
625Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A6H2EE76A0A6H2EE76_DROME
Scalloped, isoform V
sd anon-EST:Liang-2.14, clone 2.14, Dmel\CG8544, DROEXO, DROEXO2
747Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE014298 Genomic DNA Translation: ABW09420.1
AE014298 Genomic DNA Translation: AFH07409.1
AE014298 Genomic DNA Translation: AFH07414.1
AE014298 Genomic DNA Translation: AFH07415.1
AE014298 Genomic DNA Translation: ALI51151.1

NCBI Reference Sequences

More...
RefSeqi
NP_001096989.1, NM_001103519.3
NP_001245696.1, NM_001258767.2
NP_001245701.1, NM_001258772.2
NP_001245702.1, NM_001258773.2
NP_001303566.1, NM_001316637.1

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0112824; FBpp0111736; FBgn0003345
FBtr0308128; FBpp0300450; FBgn0003345
FBtr0308133; FBpp0300455; FBgn0003345
FBtr0308134; FBpp0300456; FBgn0003345
FBtr0346799; FBpp0312377; FBgn0003345

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
32536

UCSC genome browser

More...
UCSCi
CG8544-RD, d. melanogaster

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014298 Genomic DNA Translation: ABW09420.1
AE014298 Genomic DNA Translation: AFH07409.1
AE014298 Genomic DNA Translation: AFH07414.1
AE014298 Genomic DNA Translation: AFH07415.1
AE014298 Genomic DNA Translation: ALI51151.1
RefSeqiNP_001096989.1, NM_001103519.3
NP_001245696.1, NM_001258767.2
NP_001245701.1, NM_001258772.2
NP_001245702.1, NM_001258773.2
NP_001303566.1, NM_001316637.1

3D structure databases

SMRiA8JUY5
ModBaseiSearch...

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
32536

Genome annotation databases

EnsemblMetazoaiFBtr0112824; FBpp0111736; FBgn0003345
FBtr0308128; FBpp0300450; FBgn0003345
FBtr0308133; FBpp0300455; FBgn0003345
FBtr0308134; FBpp0300456; FBgn0003345
FBtr0346799; FBpp0312377; FBgn0003345
GeneIDi32536
UCSCiCG8544-RD, d. melanogaster

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
32536
FlyBaseiFBgn0003345, sd

Phylogenomic databases

GeneTreeiENSGT00950000182956
HOGENOMiCLU_012515_1_0_1
OrthoDBi823827at2759

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
32536, 0 hits in 3 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
sd, fly

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
32536

Gene expression databases

BgeeiFBgn0003345, Expressed in eye disc (Drosophila) and 59 other tissues
ExpressionAtlasiA8JUY5, baseline and differential

Family and domain databases

Gene3Di1.10.10.1610, 1 hit
InterProiView protein in InterPro
IPR000818, TEA/ATTS_dom
IPR038096, TEA/ATTS_sf
IPR016361, TEF_metazoa
IPR041086, YBD
PfamiView protein in Pfam
PF01285, TEA, 1 hit
PF17725, YBD, 1 hit
PIRSFiPIRSF002603, TEF, 2 hits
PRINTSiPR00065, TEADOMAIN
SMARTiView protein in SMART
SM00426, TEA, 1 hit
PROSITEiView protein in PROSITE
PS00554, TEA_1, 1 hit
PS51088, TEA_2, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA8JUY5_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A8JUY5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: December 4, 2007
Last sequence update: December 4, 2007
Last modified: June 2, 2021
This is version 117 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
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