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Protein
Submitted name:

ABC transporter, multidrug resistance associated protein

Gene

MRP2

Organism
Chlamydomonas reinhardtii (Chlamydomonas smithii)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi455 – 462ATPPROSITE-ProRule annotation8
Nucleotide bindingi1196 – 1203ATPPROSITE-ProRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandATP-bindingPROSITE-ProRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
ABC transporter, multidrug resistance associated proteinImported
Gene namesi
Name:MRP2Imported
ORF Names:CHLREDRAFT_190380Imported
OrganismiChlamydomonas reinhardtii (Chlamydomonas smithii)
Taxonomic identifieri3055 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeChlorophytaChlorophyceaeChlamydomonadalesChlamydomonadaceaeChlamydomonas

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei103 – 125HelicalSequence analysisAdd BLAST23
Transmembranei151 – 171HelicalSequence analysisAdd BLAST21
Transmembranei228 – 245HelicalSequence analysisAdd BLAST18
Transmembranei251 – 269HelicalSequence analysisAdd BLAST19
Transmembranei333 – 357HelicalSequence analysisAdd BLAST25
Transmembranei363 – 383HelicalSequence analysisAdd BLAST21
Transmembranei777 – 797HelicalSequence analysisAdd BLAST21
Transmembranei843 – 862HelicalSequence analysisAdd BLAST20
Transmembranei926 – 957HelicalSequence analysisAdd BLAST32
Transmembranei1027 – 1051HelicalSequence analysisAdd BLAST25
Transmembranei1057 – 1078HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiA8IW55

Expressioni

Gene expression databases

ExpressionAtlasiA8IW55 baseline

Interactioni

Protein-protein interaction databases

STRINGi3055.EDP03509

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini104 – 380ABC transmembrane type-1InterPro annotationAdd BLAST277
Domaini420 – 643ABC transporterInterPro annotationAdd BLAST224
Domaini782 – 1086ABC transmembrane type-1InterPro annotationAdd BLAST305
Domaini1162 – 1395ABC transporterInterPro annotationAdd BLAST234

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili704 – 727Sequence analysisAdd BLAST24

Keywords - Domaini

Coiled coilSequence analysis, RepeatSAAS annotation, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG0054 Eukaryota
COG1132 LUCA
InParanoidiA8IW55
KOiK05665

Family and domain databases

Gene3Di1.20.1560.10, 2 hits
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR011527 ABC1_TM_dom
IPR036640 ABC1_TM_sf
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00664 ABC_membrane, 2 hits
PF00005 ABC_tran, 2 hits
SMARTiView protein in SMART
SM00382 AAA, 2 hits
SUPFAMiSSF52540 SSF52540, 2 hits
SSF90123 SSF90123, 2 hits
PROSITEiView protein in PROSITE
PS50929 ABC_TM1F, 2 hits
PS00211 ABC_TRANSPORTER_1, 2 hits
PS50893 ABC_TRANSPORTER_2, 2 hits

Sequencei

Sequence statusi: Complete.

A8IW55-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAEVPRRQAL TKYDKAALAK ENIRNDTFIE RLFLTWVYAV VGKGRKGTIK
60 70 80 90 100
PEELRMPGDQ AAEVAVSKFD AAWAEELKLR NSGDATKKPS LVRALRRSFG
110 120 130 140 150
VDVLIAAAWK LTWSCFVLVG AFYFVRSLVQ YVTPVEKQGN MYNRTSIPGK
160 170 180 190 200
GLGWILSTMF FLDSILVGIA LQRMGDACVR VGIKIRAALM AAVYRKTFRI
210 220 230 240 250
HNVHEENVVS LVATDCAKLY EGVAHLQNVW TAPLEAVAII ALLLYLTNGT
260 270 280 290 300
YGLPALGVVV FILPLQYYLG YRIAKYKLET VEVSDARVQR MHEVLLAIKL
310 320 330 340 350
VKFYVWEKSF AKQVSDVRVQ EIKLMSRTAV IKTINLCVVF AVPPLIALVI
360 370 380 390 400
FATYVFNKGP FDSTFAFTVL SLFNTLRFPL VVLPKALRGS SEAVASLQRL
410 420 430 440 450
ERYMLLDEFE DAPKSKIVEA RFDNAVLSYP GSKEDFRLSI PSFEVKSGEV
460 470 480 490 500
VAVVGRVGSG KSSIFQAVLN HMNLESGALH VGGLMAYVPQ TPWVQNLTLR
510 520 530 540 550
DNITFGLPFD EDKYKKVVHA CALELDLQIL PKGDQTMAGE RGINLSGGQR
560 570 580 590 600
QRVCLARAAY HDCDLILLDN PLSAVDQHTA RHIFDKCIKG IFKDKAVIWI
610 620 630 640 650
THQLELLPEV TNICITDGGK SLYFGPYNPE ALNKHLPVDH LLFATVEAGE
660 670 680 690 700
SGVQQKPAEG EKKDEEQPEK KSNTIEGWKH KDSDGRKSFQ RSSKAGIRPS
710 720 730 740 750
DSVQDSLNKL AQEEEKQAEE ARSHERRSAE QRKSGQRPLG RVSEEVNPAA
760 770 780 790 800
LDETPEEIAA LFNGVPRRVT VGQSFMVYVR SGGLFLFIVS MCIFAFTQTV
810 820 830 840 850
RILSDTWIRW WASPDYFGFY PSGSFKNYIN SDPKYDTMDA ASTAYICGYF
860 870 880 890 900
GFVMLFVICL LCRDTLFSFW HLRGAIKLHN DLYFRVLRAP LLFFLRTPVG
910 920 930 940 950
DILNAFAKDM DTIDETLPDT LHMSTIYLMI LLTSLGIVTS ALYIYAALTG
960 970 980 990 1000
ALFLAFFTMQ QVYLPAATVM KRWAGETSSM VFVHVDESLH GMEVIKAFDA
1010 1020 1030 1040 1050
ENYFIQENLR RINENHLSVF NTEQCHLWLA FWCDFYGAVM VLATCLLSVA
1060 1070 1080 1090 1100
YKEDVGPAAV GLAISNTIQV LVFFTWVVRG AADTVSMWDA VERIATFVSN
1110 1120 1130 1140 1150
VPQEADLAPA PLPGAAAPGA SAGNLAGMGD KSKSLVEIKV EGDGLVSADG
1160 1170 1180 1190 1200
EPPKDWPTQG DIRFEKVCLR YYPGAPLALK YVSFHIKDGE KIGVVGRTGS
1210 1220 1230 1240 1250
GKTTLLMALF RMFELAYGRI VIDGINMANI KLQKVRAGIA IIPQEPVMFK
1260 1270 1280 1290 1300
GTVRSNLDPF GEQPDGELWR ALELVHLKEA VAELGGLDSA VAEGGSNFSL
1310 1320 1330 1340 1350
GQKQLVCMAR CVLKRTRILV LDEATAAMDL QTDALIQKTI RKAFADRTTV
1360 1370 1380 1390 1400
TIAHRLDTII FSDRILAMAA GQLKEFDSPT TLLKSPASFF TKLVEDTGPH
1410
ASKMLRRMAA EGPKDEE
Length:1,417
Mass (Da):157,430
Last modified:December 4, 2007 - v1
Checksum:iA70CB6311CF889C5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS496125 Genomic DNA Translation: EDP03509.1
RefSeqiXP_001692940.1, XM_001692888.1
UniGeneiCre.13776

Genome annotation databases

EnsemblPlantsiEDP03509; EDP03509; CHLREDRAFT_190380
GeneIDi5718626
GrameneiEDP03509; EDP03509; CHLREDRAFT_190380
KEGGicre:CHLREDRAFT_190380

Similar proteinsi

Entry informationi

Entry nameiA8IW55_CHLRE
AccessioniPrimary (citable) accession number: A8IW55
Entry historyiIntegrated into UniProtKB/TrEMBL: December 4, 2007
Last sequence update: December 4, 2007
Last modified: May 23, 2018
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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