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Protein

60 kDa chaperonin 2

Gene

groL2

Organism
Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / NBRC 14845 / NCIMB 13405 / ORS 571)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciACAU438753:G1G2W-2427-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
60 kDa chaperonin 2UniRule annotation
Alternative name(s):
GroEL protein 2UniRule annotation
Protein Cpn60 2UniRule annotation
Gene namesi
Name:groL2UniRule annotation
Synonyms:groEL2UniRule annotation
Ordered Locus Names:AZC_2312
OrganismiAzorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / NBRC 14845 / NCIMB 13405 / ORS 571)
Taxonomic identifieri438753 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesXanthobacteraceaeAzorhizobium
Proteomesi
  • UP000000270 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003319731 – 54260 kDa chaperonin 2Add BLAST542

Proteomic databases

PRIDEiA8I5R5

Interactioni

Subunit structurei

Oligomer of 14 subunits composed of two stacked rings of 7 subunits.UniRule annotation

Protein-protein interaction databases

STRINGi438753.AZC_2312

Structurei

3D structure databases

ProteinModelPortaliA8I5R5
SMRiA8I5R5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chaperonin (HSP60) family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CJ9 Bacteria
COG0459 LUCA
HOGENOMiHOG000076290
KOiK04077
OMAiCVIKVGA
OrthoDBiPOG091H00E7

Family and domain databases

CDDicd03344 GroEL, 1 hit
Gene3Di1.10.560.10, 2 hits
3.30.260.10, 2 hits
3.50.7.10, 1 hit
HAMAPiMF_00600 CH60, 1 hit
InterProiView protein in InterPro
IPR018370 Chaperonin_Cpn60_CS
IPR001844 Chaprnin_Cpn60
IPR002423 Cpn60/TCP-1
IPR027409 GroEL-like_apical_dom_sf
IPR027413 GROEL-like_equatorial_sf
IPR027410 TCP-1-like_intermed_sf
PfamiView protein in Pfam
PF00118 Cpn60_TCP1, 1 hit
PRINTSiPR00298 CHAPERONIN60
SUPFAMiSSF48592 SSF48592, 2 hits
SSF52029 SSF52029, 1 hit
SSF54849 SSF54849, 1 hit
TIGRFAMsiTIGR02348 GroEL, 1 hit
PROSITEiView protein in PROSITE
PS00296 CHAPERONINS_CPN60, 1 hit

Sequencei

Sequence statusi: Complete.

A8I5R5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAKDVKFAG DAREKMLRGV DILANAVKVT LGPKGRNVVI EKSFGAPRIT
60 70 80 90 100
KDGVSVAKEI ELEDKFENLG AQLVREVASK TNDLAGDGTT TATVLAQAIV
110 120 130 140 150
KEGSKAVAAG MNPMDLKRGI DLAVDAIVKD LAAKAKKVTS NAEIAQVGTI
160 170 180 190 200
SANGDADVGK FLAEAMQKVG NEGVITVEEA KTAETELEVV EGMQFDRGYL
210 220 230 240 250
SPYFVTNAEK MRVEFEDPYI LIHEKKLSNL QELLPVLEAV VQSGKPLVIV
260 270 280 290 300
AEDVEGEALA TLVVNKLRGG LKVAAVKAPG FGDRRKAMLQ DIAILTGGQA
310 320 330 340 350
ISEDLGIKLE NVNLSMLGRA KKVVIEKENT TIVDGNGEKA DIEARVAQIK
360 370 380 390 400
AQIEETTSDY DREKLQERLA KLAGGVAVIR VGGATEVEVK EKKDRVDDAL
410 420 430 440 450
HATRAAVEEG IVPGGGVALL RAIKVLEGLK VENTDQKTGI DIVRRAIQAP
460 470 480 490 500
ARQIVANAGD DGSVVVGKIL ENETYTFGYN AQTGEYVDMV ASGIIDPAKV
510 520 530 540
VRTALQDAAS ISALIITTEA LVVELPKKAA AAPAMPGGGM DF
Length:542
Mass (Da):57,309
Last modified:December 4, 2007 - v1
Checksum:i8E98D286A997D4E9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP009384 Genomic DNA Translation: BAF88310.1
RefSeqiWP_012170839.1, NC_009937.1

Genome annotation databases

EnsemblBacteriaiBAF88310; BAF88310; AZC_2312
KEGGiazc:AZC_2312

Similar proteinsi

Entry informationi

Entry nameiCH602_AZOC5
AccessioniPrimary (citable) accession number: A8I5R5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: December 4, 2007
Last modified: May 23, 2018
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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