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Protein

Probable malate:quinone oxidoreductase

Gene

mqo

Organism
Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / NBRC 14845 / NCIMB 13405 / ORS 571)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

(S)-malate + a quinone = oxaloacetate + reduced quinone.UniRule annotation

Cofactori

FADUniRule annotation

Pathwayi: tricarboxylic acid cycle

This protein is involved in step 1 of the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route).UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Probable malate:quinone oxidoreductase (mqo)
This subpathway is part of the pathway tricarboxylic acid cycle, which is itself part of Carbohydrate metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route), the pathway tricarboxylic acid cycle and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
Biological processTricarboxylic acid cycle
LigandFAD, Flavoprotein

Enzyme and pathway databases

BioCyciACAU438753:G1G2W-1974-MONOMER
UniPathwayiUPA00223; UER01008

Names & Taxonomyi

Protein namesi
Recommended name:
Probable malate:quinone oxidoreductaseUniRule annotation (EC:1.1.5.4UniRule annotation)
Alternative name(s):
MQOUniRule annotation
Malate dehydrogenase [quinone]UniRule annotation
Gene namesi
Name:mqoUniRule annotation
Ordered Locus Names:AZC_1899
OrganismiAzorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / NBRC 14845 / NCIMB 13405 / ORS 571)
Taxonomic identifieri438753 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesXanthobacteraceaeAzorhizobium
Proteomesi
  • UP000000270 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000717471 – 500Probable malate:quinone oxidoreductaseAdd BLAST500

Interactioni

Protein-protein interaction databases

STRINGi438753.AZC_1899

Structurei

3D structure databases

ProteinModelPortaliA8I2M2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MQO family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DWT Bacteria
COG0579 LUCA
HOGENOMiHOG000109379
KOiK00116
OMAiPQHDMAL
OrthoDBiPOG091H0B7C

Family and domain databases

Gene3Di3.50.50.60, 2 hits
HAMAPiMF_00212 MQO, 1 hit
InterProiView protein in InterPro
IPR036188 FAD/NAD-bd_sf
IPR006231 MQO
PfamiView protein in Pfam
PF06039 Mqo, 1 hit
SUPFAMiSSF51905 SSF51905, 1 hit
TIGRFAMsiTIGR01320 mal_quin_oxido, 1 hit

Sequencei

Sequence statusi: Complete.

A8I2M2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTFSQKTDTD VLLIGAGIMS ATLGTLLHAL EPSLRLTMLE RLDDCGLESS
60 70 80 90 100
MGWNNAGTGH AANCELNYTP QRADGSVDIS KALQVNTQFD ISRELWSHLV
110 120 130 140 150
TTGAIPDPRA FLHPCPHMSF VWGEENVAFL KARHAAMAAH HCYHGMDYSE
160 170 180 190 200
DPAQIAQWAP LVMEGRDPAQ KIAATRIITG TDVDYGALTH LLVGHLKTAG
210 220 230 240 250
LDLRYNSEVI AIDRGDDGIW TVTFEDTVDG TRQQITAGFV FIGAGGAAIE
260 270 280 290 300
LLQKSGIPEA KGYAGFPVSG IWLRCDVDAV AARHHAKVYG KAASGSPPMS
310 320 330 340 350
VPHLDTRVIG GKTSLLFGPY AGFSTKFLKR GSLTDLFGSI TASNILPLLD
360 370 380 390 400
VAKDNAALEE YLIGQVFQSR HHQFEMLRQF FPQARRADWQ EAVAGQRVQI
410 420 430 440 450
IKPDQGDPGG QLEFGTELVA ASDKSLVALL GASPGASTAA AIAVHVLQTC
460 470 480 490 500
FADRLTEDGW LPALRGALPS YGIDLITDAE ACSASRKATA KVLKIDNIDA
Length:500
Mass (Da):53,645
Last modified:December 4, 2007 - v1
Checksum:i0B2ABC3849EEA6D2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP009384 Genomic DNA Translation: BAF87897.1
RefSeqiWP_012170427.1, NC_009937.1

Genome annotation databases

EnsemblBacteriaiBAF87897; BAF87897; AZC_1899
KEGGiazc:AZC_1899

Similar proteinsi

Entry informationi

Entry nameiMQO_AZOC5
AccessioniPrimary (citable) accession number: A8I2M2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: December 4, 2007
Last modified: February 28, 2018
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

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