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Protein

Peptidyl-tRNA hydrolase

Gene

pth

Organism
Rickettsia rickettsii (strain Sheila Smith)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.UniRule annotation

Catalytic activityi

N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Peptidyl-tRNA hydrolaseUniRule annotation (EC:3.1.1.29UniRule annotation)
Short name:
PTHUniRule annotation
Gene namesi
Name:pthUniRule annotation
Ordered Locus Names:A1G_05130
OrganismiRickettsia rickettsii (strain Sheila Smith)
Taxonomic identifieri392021 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
Proteomesi
  • UP000006832 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000106431 – 185Peptidyl-tRNA hydrolaseAdd BLAST185

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliA8GSZ4
SMRiA8GSZ4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PTH family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000004797
KOiK01056
OMAiRYAHTRH

Family and domain databases

CDDicd00462 PTH, 1 hit
Gene3Di3.40.50.1470, 1 hit
HAMAPiMF_00083 Pept_tRNA_hydro_bact, 1 hit
InterProiView protein in InterPro
IPR001328 Pept_tRNA_hydro
IPR018171 Pept_tRNA_hydro_CS
IPR036416 Pept_tRNA_hydro_sf
PANTHERiPTHR17224 PTHR17224, 1 hit
PfamiView protein in Pfam
PF01195 Pept_tRNA_hydro, 1 hit
SUPFAMiSSF53178 SSF53178, 1 hit
TIGRFAMsiTIGR00447 pth, 1 hit
PROSITEiView protein in PROSITE
PS01195 PEPT_TRNA_HYDROL_1, 1 hit
PS01196 PEPT_TRNA_HYDROL_2, 1 hit

Sequencei

Sequence statusi: Complete.

A8GSZ4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLLVIGLGNP GKEYQYTRHN VGFIAIEKIA NQYNSSFSTK KKFNCEIAET
60 70 80 90 100
ISYGQKIIFI KPTTYMNLSG KSVISVKTYY NIYPAKSFVI HDDIDLETGR
110 120 130 140 150
VKFKTGGGNG GHNGLKSIDG VIGNNYNRIR IGVGRPQNNQ DLADYVLNHF
160 170 180
SKPEYKTVMQ AIDRITSNFG LILENKLEEF KNKMA
Length:185
Mass (Da):20,827
Last modified:November 13, 2007 - v1
Checksum:i3AAECB685D7DB698
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000848 Genomic DNA Translation: ABV76519.1
RefSeqiWP_012151089.1, NC_009882.1

Genome annotation databases

EnsemblBacteriaiABV76519; ABV76519; A1G_05130
KEGGirri:A1G_05130

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000848 Genomic DNA Translation: ABV76519.1
RefSeqiWP_012151089.1, NC_009882.1

3D structure databases

ProteinModelPortaliA8GSZ4
SMRiA8GSZ4
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABV76519; ABV76519; A1G_05130
KEGGirri:A1G_05130

Phylogenomic databases

HOGENOMiHOG000004797
KOiK01056
OMAiRYAHTRH

Family and domain databases

CDDicd00462 PTH, 1 hit
Gene3Di3.40.50.1470, 1 hit
HAMAPiMF_00083 Pept_tRNA_hydro_bact, 1 hit
InterProiView protein in InterPro
IPR001328 Pept_tRNA_hydro
IPR018171 Pept_tRNA_hydro_CS
IPR036416 Pept_tRNA_hydro_sf
PANTHERiPTHR17224 PTHR17224, 1 hit
PfamiView protein in Pfam
PF01195 Pept_tRNA_hydro, 1 hit
SUPFAMiSSF53178 SSF53178, 1 hit
TIGRFAMsiTIGR00447 pth, 1 hit
PROSITEiView protein in PROSITE
PS01195 PEPT_TRNA_HYDROL_1, 1 hit
PS01196 PEPT_TRNA_HYDROL_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiPTH_RICRS
AccessioniPrimary (citable) accession number: A8GSZ4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: November 13, 2007
Last modified: October 10, 2018
This is version 60 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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Main funding by: National Institutes of Health

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