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Protein

Ribosomal RNA small subunit methyltransferase B

Gene

rsmB

Organism
Serratia proteamaculans (strain 568)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + cytosine(967) in 16S rRNA = S-adenosyl-L-homocysteine + 5-methylcytosine(967) in 16S rRNA.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei277S-adenosyl-L-methionineUniRule annotation1
Binding sitei303S-adenosyl-L-methionineUniRule annotation1
Binding sitei322S-adenosyl-L-methionineUniRule annotation1
Active sitei375NucleophileUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMethyltransferase, RNA-binding, Transferase
Biological processrRNA processing
LigandS-adenosyl-L-methionine

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosomal RNA small subunit methyltransferase BUniRule annotation (EC:2.1.1.176UniRule annotation)
Alternative name(s):
16S rRNA m5C967 methyltransferaseUniRule annotation
rRNA (cytosine-C(5)-)-methyltransferase RsmBUniRule annotation
Gene namesi
Name:rsmBUniRule annotation
Synonyms:sunUniRule annotation
Ordered Locus Names:Spro_4513
OrganismiSerratia proteamaculans (strain 568)
Taxonomic identifieri399741 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesYersiniaceaeSerratia
Proteomesi
  • UP000007074 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003661751 – 429Ribosomal RNA small subunit methyltransferase BAdd BLAST429

Proteomic databases

PRIDEiA8GKG7

Interactioni

Protein-protein interaction databases

STRINGi399741.Spro_4513

Structurei

3D structure databases

ProteinModelPortaliA8GKG7
SMRiA8GKG7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni254 – 260S-adenosyl-L-methionine bindingUniRule annotation7

Sequence similaritiesi

Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CYJ Bacteria
COG0144 LUCA
HOGENOMiHOG000037300
KOiK03500
OMAiLRVNRQH
OrthoDBiPOG091H02E2

Family and domain databases

Gene3Di1.10.940.10, 1 hit
HAMAPiMF_01856 16SrRNA_methyltr_B, 1 hit
InterProiView protein in InterPro
IPR018314 Fmu/NOL1/Nop2p_CS
IPR001678 MeTrfase_RsmB/NOP2
IPR035926 NusB-like_sf
IPR006027 NusB_RsmB_TIM44
IPR023267 RCMT
IPR004573 rRNA_ssu_MeTfrase_B
IPR023541 rRNA_ssu_MeTfrase_B_ent
IPR029063 SAM-dependent_MTases
PfamiView protein in Pfam
PF01189 Methyltr_RsmB-F, 1 hit
PF01029 NusB, 1 hit
PRINTSiPR02008 RCMTFAMILY
SUPFAMiSSF48013 SSF48013, 1 hit
SSF53335 SSF53335, 1 hit
TIGRFAMsiTIGR00563 rsmB, 1 hit
PROSITEiView protein in PROSITE
PS01153 NOL1_NOP2_SUN, 1 hit
PS51686 SAM_MT_RSMB_NOP, 1 hit

Sequencei

Sequence statusi: Complete.

A8GKG7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKNNYNLRSI AAIAIGQVLD QGQSLSTVLP SLQKTISDKD RALLQELCFG
60 70 80 90 100
TLRVLPQLEW CIQQLMAKPM TGKQRTLHYL LMVGLYQLLY TRIPAHAVLA
110 120 130 140 150
ETVEGAVALK RPQLKGLING VLRQFQRQQE ELLQRAANND SRYLHPSWLL
160 170 180 190 200
KRIQQAYPAQ WEQIIDANNQ KPPMWLRVNR LHHTREDYLQ LMEQAGIAAE
210 220 230 240 250
PHAEYRDAVR LLAPCAVTDL PGFADGWVTV QDASAQGCVD LLDPQDGEQI
260 270 280 290 300
LDLCAAPGGK TTHILEAAPK AHVMAVDIDE QRLKRVKENL QRLRLHAEVK
310 320 330 340 350
QGDGRTPQQW CGDKQFDRIL LDAPCSATGV IRRHPDIKWL RRDSDIAELA
360 370 380 390 400
ALQAEIIEAI WPHLKSGGVM VYATCSILPA ENAEQVSAFL QRHADARLVE
410 420
TGNQQQPGRQ NLPHPEDGDG FFYAKLIKM
Length:429
Mass (Da):48,279
Last modified:November 13, 2007 - v1
Checksum:i9594F2D5FA8D9B0A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000826 Genomic DNA Translation: ABV43607.1
RefSeqiWP_012147207.1, NC_009832.1

Genome annotation databases

EnsemblBacteriaiABV43607; ABV43607; Spro_4513
KEGGispe:Spro_4513

Similar proteinsi

Entry informationi

Entry nameiRSMB_SERP5
AccessioniPrimary (citable) accession number: A8GKG7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: November 13, 2007
Last modified: March 28, 2018
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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