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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Campylobacter jejuni subsp. jejuni serotype O:6 (strain 81116 / NCTC 11828)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciCJEJ407148:G1G9V-1156-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:C8J_1119
OrganismiCampylobacter jejuni subsp. jejuni serotype O:6 (strain 81116 / NCTC 11828)
Taxonomic identifieri407148 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeCampylobacter

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000713941 – 530Arginine--tRNA ligaseAdd BLAST530

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliA8FMN1
SMRiA8FMN1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi113 – 123"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000247214
KOiK01887
OMAiNKPLHLG

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

A8FMN1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKSIIFNEIK KILECDFTLE NPKDKNLAHF ATPLAFSLAK ELKKSPMLIA
60 70 80 90 100
SDLASKFQNH DCFESVEAVN GYLNFRISKT FLNELANQAL ANPNDFSKGE
110 120 130 140 150
KKQESFLLEY VSANPTGPLH IGHARGAVFG DTLTRLARHL GYKFDTEYYV
160 170 180 190 200
NDAGNQIYLL GLSILLSVKE NILHENVEYP EQYYKGEYIA DLAKEAFEKF
210 220 230 240 250
GKEFFSEENI PSLADWAKDK MLILIKQNLE QAKIKIDSYV SERSYYDALN
260 270 280 290 300
ATLESLKEHK GIYEQEGKIW LASSQKGDEK DRVIIREDGR GTYLAADIVY
310 320 330 340 350
HKDKMSRGYG KCINIWGADH HGYIPRMKAA MEFLGFDSNN LEIILAQMVS
360 370 380 390 400
LLKDGEPYKM SKRAGNFILM SDVIDEIGSD ALRYIFLSKK CDTHLEFDIS
410 420 430 440 450
DLQKEDSSNP VYYINYAHAR IHQVFAKAGK KIDDVMRADL QSLNQDGVNL
460 470 480 490 500
LFEALNLKAI LNDAFEARAL QKIPDYLKNL AANFHKFYNE NKVVGSINEN
510 520 530
DLLKLFSLVA LSIKTAFSLM GIEAKNKMEH
Length:530
Mass (Da):60,288
Last modified:November 13, 2007 - v1
Checksum:i072148F35A09AD1C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000814 Genomic DNA Translation: ABV52718.1
RefSeqiWP_002866187.1, NC_009839.1

Genome annotation databases

EnsemblBacteriaiABV52718; ABV52718; C8J_1119
KEGGicju:C8J_1119

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000814 Genomic DNA Translation: ABV52718.1
RefSeqiWP_002866187.1, NC_009839.1

3D structure databases

ProteinModelPortaliA8FMN1
SMRiA8FMN1
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABV52718; ABV52718; C8J_1119
KEGGicju:C8J_1119

Phylogenomic databases

HOGENOMiHOG000247214
KOiK01887
OMAiNKPLHLG

Enzyme and pathway databases

BioCyciCJEJ407148:G1G9V-1156-MONOMER

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiSYR_CAMJ8
AccessioniPrimary (citable) accession number: A8FMN1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: November 13, 2007
Last modified: October 10, 2018
This is version 66 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
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Main funding by: National Institutes of Health

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