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Entry version 81 (13 Feb 2019)
Sequence version 1 (13 Nov 2007)
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Protein
Submitted name:

Ion transport protein

Gene

Abu_1752

Organism
Arcobacter butzleri (strain RM4018)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • identical protein binding Source: IntAct
  • ion channel activity Source: InterPro

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
ABUT367737:G1G6I-1758-MONOMER

Protein family/group databases

Transport Classification Database

More...
TCDBi
1.A.1.14.5 the voltage-gated ion channel (vic) superfamily

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Ion transport proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:Abu_1752Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArcobacter butzleri (strain RM4018)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri367737 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeArcobacter groupArcobacter
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001136 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei12 – 31HelicalSequence analysisAdd BLAST20
Transmembranei43 – 66HelicalSequence analysisAdd BLAST24
Transmembranei78 – 98HelicalSequence analysisAdd BLAST21
Transmembranei119 – 147HelicalSequence analysisAdd BLAST29
Transmembranei193 – 218HelicalSequence analysisAdd BLAST26

GO - Cellular componenti

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
itself3EBI-15936203,EBI-15936203

GO - Molecular functioni

Protein-protein interaction databases

Database of interacting proteins

More...
DIPi
DIP-59168N

STRING: functional protein association networks

More...
STRINGi
367737.Abu_1752

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3RVYX-ray2.70A/B1-267[»]
3RVZX-ray2.80A/B1-267[»]
3RW0X-ray2.95A/B1-267[»]
4EKWX-ray3.21A/B/C/D1-267[»]
4MS2X-ray2.75A/B/C/D1-219[»]
4MTFX-ray3.20A/B/C/D1-219[»]
4MTGX-ray3.30A/B/C/D1-219[»]
4MTOX-ray3.40A/B/C/D1-219[»]
4MVMX-ray3.20A/B/C/D1-219[»]
4MVOX-ray3.30A/B/C/D1-219[»]
4MVQX-ray3.40A/B/C/D1-219[»]
4MVRX-ray3.20A/B/C/D1-219[»]
4MVSX-ray3.30A/B/C/D1-219[»]
4MVUX-ray3.20A/B/C/D1-219[»]
4MVZX-ray3.30A/B/C/D1-219[»]
4MW3X-ray3.30A/B/C/D1-219[»]
4MW8X-ray3.26A/B/C/D1-219[»]
5EK0X-ray3.53A/B/C/D1-25[»]
A/B/C/D58-81[»]
A/B/C/D111-267[»]
5KLBX-ray2.70A/B/C/D1-267[»]
5KLGX-ray3.30A/B/C/D1-267[»]
5KLSX-ray3.30A/B/C/D1-267[»]
5KMDX-ray3.20A/B/C/D1-267[»]
5KMFX-ray3.20A/B/C/D1-267[»]
5KMHX-ray3.20A/B/C/D1-267[»]
5VB2X-ray3.20A/B/C/D1-267[»]
5VB8X-ray2.85A1-226[»]
5YUAX-ray2.80A1-267[»]
5YUBX-ray3.40A1-267[»]
5YUCX-ray3.40A1-267[»]
6C1EX-ray2.86A/B1-267[»]
6C1KX-ray2.70A/B1-267[»]
6C1MX-ray2.52A/B1-267[»]
6C1PX-ray2.90A/B/C/D1-267[»]
6MVVX-ray2.90A/B/C/D1-267[»]
6MVWX-ray3.20A/B/C/D1-267[»]
6MVXX-ray3.46A/B/C/D1-267[»]
6MVYX-ray3.00A/B1-226[»]

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
A8EVM5

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
A8EVM5

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini12 – 228Ion_transInterPro annotationAdd BLAST217

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili233 – 267Sequence analysisAdd BLAST35

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG4105D68 Bacteria
COG1226 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000004763

KEGG Orthology (KO)

More...
KOi
K08714

Identification of Orthologs from Complete Genome Data

More...
OMAi
WKDGYNL

Database of Orthologous Groups

More...
OrthoDBi
1280139at2

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.120.350, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR005821 Ion_trans_dom
IPR027359 Volt_channel_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00520 Ion_trans, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A8EVM5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MYLRITNIVE SSFFTKFIIY LIVLNGITMG LETSKTFMQS FGVYTTLFNQ
60 70 80 90 100
IVITIFTIEI ILRIYVHRIS FFKDPWSLFD FFVVAISLVP TSSGFEILRV
110 120 130 140 150
LRVLRLFRLV TAVPQMRKIV SALISVIPGM LSVIALMTLF FYIFAIMATQ
160 170 180 190 200
LFGERFPEWF GTLGESFYTL FQVMTLESWS MGIVRPLMEV YPYAWVFFIP
210 220 230 240 250
FIFVVTFVMI NLVVAIIVDA MAILNQKEEQ HIIDEVQSHE DNINNEIIKL
260
REEIVELKEL IKTSLKN
Length:267
Mass (Da):31,071
Last modified:November 13, 2007 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0BC9D03C5E94038B
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CP000361 Genomic DNA Translation: ABV67998.1

NCBI Reference Sequences

More...
RefSeqi
WP_012147720.1, NC_009850.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
ABV67998; ABV67998; Abu_1752

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
24303594

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
abu:Abu_1752

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000361 Genomic DNA Translation: ABV67998.1
RefSeqiWP_012147720.1, NC_009850.1

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3RVYX-ray2.70A/B1-267[»]
3RVZX-ray2.80A/B1-267[»]
3RW0X-ray2.95A/B1-267[»]
4EKWX-ray3.21A/B/C/D1-267[»]
4MS2X-ray2.75A/B/C/D1-219[»]
4MTFX-ray3.20A/B/C/D1-219[»]
4MTGX-ray3.30A/B/C/D1-219[»]
4MTOX-ray3.40A/B/C/D1-219[»]
4MVMX-ray3.20A/B/C/D1-219[»]
4MVOX-ray3.30A/B/C/D1-219[»]
4MVQX-ray3.40A/B/C/D1-219[»]
4MVRX-ray3.20A/B/C/D1-219[»]
4MVSX-ray3.30A/B/C/D1-219[»]
4MVUX-ray3.20A/B/C/D1-219[»]
4MVZX-ray3.30A/B/C/D1-219[»]
4MW3X-ray3.30A/B/C/D1-219[»]
4MW8X-ray3.26A/B/C/D1-219[»]
5EK0X-ray3.53A/B/C/D1-25[»]
A/B/C/D58-81[»]
A/B/C/D111-267[»]
5KLBX-ray2.70A/B/C/D1-267[»]
5KLGX-ray3.30A/B/C/D1-267[»]
5KLSX-ray3.30A/B/C/D1-267[»]
5KMDX-ray3.20A/B/C/D1-267[»]
5KMFX-ray3.20A/B/C/D1-267[»]
5KMHX-ray3.20A/B/C/D1-267[»]
5VB2X-ray3.20A/B/C/D1-267[»]
5VB8X-ray2.85A1-226[»]
5YUAX-ray2.80A1-267[»]
5YUBX-ray3.40A1-267[»]
5YUCX-ray3.40A1-267[»]
6C1EX-ray2.86A/B1-267[»]
6C1KX-ray2.70A/B1-267[»]
6C1MX-ray2.52A/B1-267[»]
6C1PX-ray2.90A/B/C/D1-267[»]
6MVVX-ray2.90A/B/C/D1-267[»]
6MVWX-ray3.20A/B/C/D1-267[»]
6MVXX-ray3.46A/B/C/D1-267[»]
6MVYX-ray3.00A/B1-226[»]
SMRiA8EVM5
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-59168N
STRINGi367737.Abu_1752

Protein family/group databases

TCDBi1.A.1.14.5 the voltage-gated ion channel (vic) superfamily

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABV67998; ABV67998; Abu_1752
GeneIDi24303594
KEGGiabu:Abu_1752

Phylogenomic databases

eggNOGiENOG4105D68 Bacteria
COG1226 LUCA
HOGENOMiHOG000004763
KOiK08714
OMAiWKDGYNL
OrthoDBi1280139at2

Enzyme and pathway databases

BioCyciABUT367737:G1G6I-1758-MONOMER

Miscellaneous databases

EvolutionaryTraceiA8EVM5

Family and domain databases

Gene3Di1.20.120.350, 1 hit
InterProiView protein in InterPro
IPR005821 Ion_trans_dom
IPR027359 Volt_channel_dom_sf
PfamiView protein in Pfam
PF00520 Ion_trans, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA8EVM5_ARCB4
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A8EVM5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 13, 2007
Last sequence update: November 13, 2007
Last modified: February 13, 2019
This is version 81 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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