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Protein

UvrABC system protein C

Gene

uvrC

Organism
Arcobacter butzleri (strain RM4018)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionExcision nuclease
Biological processDNA damage, DNA excision, DNA repair, SOS response

Enzyme and pathway databases

BioCyciABUT367737:G1G6I-788-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
UvrABC system protein CUniRule annotation
Short name:
Protein UvrCUniRule annotation
Alternative name(s):
Excinuclease ABC subunit CUniRule annotation
Gene namesi
Name:uvrCUniRule annotation
Ordered Locus Names:Abu_0787
OrganismiArcobacter butzleri (strain RM4018)
Taxonomic identifieri367737 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeArcobacter
Proteomesi
  • UP000001136 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000777511 – 616UvrABC system protein CAdd BLAST616

Interactioni

Subunit structurei

Interacts with UvrB in an incision complex.UniRule annotation

Protein-protein interaction databases

STRINGi367737.Abu_0787

Structurei

3D structure databases

ProteinModelPortaliA8ESX8
SMRiA8ESX8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini12 – 97GIY-YIGUniRule annotationAdd BLAST86
Domaini203 – 238UVRUniRule annotationAdd BLAST36

Sequence similaritiesi

Belongs to the UvrC family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CII Bacteria
COG0322 LUCA
HOGENOMiHOG000279960
KOiK03703
OMAiLFPIRQC
OrthoDBiPOG091H01BS

Family and domain databases

Gene3Di3.30.420.340, 1 hit
3.40.1440.10, 1 hit
HAMAPiMF_00203 UvrC, 1 hit
InterProiView protein in InterPro
IPR000305 GIY-YIG_endonuc
IPR035901 GIY-YIG_endonuc_sf
IPR010994 RuvA_2-like
IPR001943 UVR_dom
IPR036876 UVR_dom_sf
IPR004791 UvrC
IPR001162 UvrC_homol_region
IPR038476 UvrC_homol_region_sf
PfamiView protein in Pfam
PF01541 GIY-YIG, 1 hit
PF02151 UVR, 1 hit
PF08459 UvrC_HhH_N, 1 hit
SMARTiView protein in SMART
SM00465 GIYc, 1 hit
SUPFAMiSSF46600 SSF46600, 1 hit
SSF47781 SSF47781, 1 hit
SSF82771 SSF82771, 1 hit
TIGRFAMsiTIGR00194 uvrC, 1 hit
PROSITEiView protein in PROSITE
PS50164 GIY_YIG, 1 hit
PS50151 UVR, 1 hit
PS50165 UVRC, 1 hit

Sequencei

Sequence statusi: Complete.

A8ESX8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNLQEKLQQL PNDAGVYQYF DKNGHLLYIG KAKILKNRVK SYFKFTPKLQ
60 70 80 90 100
PADKLSPRIY KMISEVESCE WIVVPNEHDA LILENSLIKQ LKPKYNILLR
110 120 130 140 150
DDKTYPYIFV DFDEDFPRLD ITRRIQKSKS IKYFGPYSTG ARDMLDSIYE
160 170 180 190 200
IVPLVQKKSC VKGKKACLFY QIQKCLAPCE NKISKEEYAK IVENALEYIY
210 220 230 240 250
NKTKLISKLN EKMLQYSNDF RFEEAMTLRD RIKTIEKSQI KSDIDLATNE
260 270 280 290 300
DIDIFAINAN NKKAVIVRMF LRDGKLTSSS HDFLKIDNFD EEFEFDYQEA
310 320 330 340 350
YERAIINYYD NEIPLLPKEI LIAHELEITN ELEEFLHTRF NKKIKLINPK
360 370 380 390 400
KDKKREIVNI ALNNCDELLR IENSKNQTSI YEELKELFNL QTLPYLIESF
410 420 430 440 450
DNSHMMGQAT VGAMIVWNES LNTFDKKAFR HYNLESKDEY SQMKEMLIRR
460 470 480 490 500
IESFEKNPAP DLWIIDGGET LLKLAFDIVQ SVGVNLDIIA IAKEKIDAKA
510 520 530 540 550
HRAKGKAKDI IHYKTKNGEF KSFNLLTSDK RLQFVQRQRD EAHRFAITFH
560 570 580 590 600
KKQKRAQDKQ ISLLQIKGIG EAKIKKLLLY FGEFEKIKKA SFDELKTVLN
610
EKDASTILDY FTNFKD
Length:616
Mass (Da):72,325
Last modified:November 13, 2007 - v1
Checksum:iF3B9FBA07F2172B9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000361 Genomic DNA Translation: ABV67052.1
RefSeqiWP_012012529.1, NC_009850.1

Genome annotation databases

EnsemblBacteriaiABV67052; ABV67052; Abu_0787
GeneIDi24305224
KEGGiabu:Abu_0787

Similar proteinsi

Entry informationi

Entry nameiUVRC_ARCB4
AccessioniPrimary (citable) accession number: A8ESX8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: November 13, 2007
Last modified: May 23, 2018
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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