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Protein

Immunoglobulin superfamily member 2

Gene

Cd101

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Plays a role as inhibitor of T-cells proliferation induced by CD3. Inhibits expression of IL2RA on activated T-cells and secretion of IL2. Inhibits tyrosine kinases that are required for IL2 production and cellular proliferation. Inhibits phospholipase C-gamma-1/PLCG1 phosphorylation and subsequent CD3-induced changes in intracellular free calcium. Prevents nuclear translocation of nuclear factor of activated T-cell to the nucleus. Plays a role in the inhibition of T-cell proliferation via IL10 secretion by cutaneous dendritic cells (By similarity).By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

  • positive regulation of myeloid leukocyte differentiation Source: MGI

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-202433 Generation of second messenger molecules

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Immunoglobulin superfamily member 2
Short name:
IgSF2
Alternative name(s):
Glu-Trp-Ile EWI motif-containing protein 101
Short name:
EWI-101
CD_antigen: CD101
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Cd101
Synonyms:Igsf2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2685862 Cd101

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini21 – 970ExtracellularSequence analysisAdd BLAST950
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei971 – 991HelicalSequence analysisAdd BLAST21
Topological domaini992 – 1033CytoplasmicSequence analysisAdd BLAST42

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 20Sequence analysisAdd BLAST20
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000036395121 – 1033Immunoglobulin superfamily member 2Add BLAST1013

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi43 ↔ 121PROSITE-ProRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi139N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi168 ↔ 249PROSITE-ProRule annotation
Disulfide bondi304 ↔ 377PROSITE-ProRule annotation
Disulfide bondi432 ↔ 509PROSITE-ProRule annotation
Disulfide bondi560 ↔ 638PROSITE-ProRule annotation
Glycosylationi677N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi695 ↔ 776PROSITE-ProRule annotation
Disulfide bondi832 ↔ 925PROSITE-ProRule annotation

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

N-glycosylated.By similarity

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
A8E0Y8

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
A8E0Y8

PRoteomics IDEntifications database

More...
PRIDEi
A8E0Y8

PTM databases

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
A8E0Y8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000086564 Expressed in 14 organ(s), highest expression level in brain

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
A8E0Y8 baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000116643

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
A8E0Y8

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini22 – 141Ig-like C2-type 1Add BLAST120
Domaini144 – 266Ig-like C2-type 2Add BLAST123
Domaini279 – 388Ig-like C2-type 3Add BLAST110
Domaini408 – 529Ig-like C2-type 4Add BLAST122
Domaini539 – 657Ig-like C2-type 5Add BLAST119
Domaini670 – 797Ig-like C2-type 6Add BLAST128
Domaini806 – 941Ig-like C2-type 7Add BLAST136

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi253 – 255EWI motif3

Keywords - Domaini

Immunoglobulin domain, Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IFBX Eukaryota
ENOG410YWQX LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000161722

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000293322

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG107997

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
A8E0Y8

KEGG Orthology (KO)

More...
KOi
K06522

Identification of Orthologs from Complete Genome Data

More...
OMAi
QAVWEGE

Database of Orthologous Groups

More...
OrthoDBi
180654at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
A8E0Y8

TreeFam database of animal gene trees

More...
TreeFami
TF332702

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.10, 7 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR003599 Ig_sub
IPR003598 Ig_sub2
IPR013106 Ig_V-set
IPR013151 Immunoglobulin

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00047 ig, 1 hit
PF07686 V-set, 3 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00409 IG, 7 hits
SM00408 IGc2, 3 hits
SM00406 IGv, 5 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48726 SSF48726, 7 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50835 IG_LIKE, 7 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

A8E0Y8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MACILCVASL FLSLTKFSIG QREVKIQEGP LYRAEGYPVS IRCTVSGHQG
60 70 80 90 100
PSTQDFRWSI YLPSAPTKEV QIISTKDAGF SYAVYAQRVQ SKEIYIERLQ
110 120 130 140 150
GDSVLLHISK LQMKDAGEYE CHTPNTDGKY FGSYSAKTNL TVVPDTLSAT
160 170 180 190 200
MPSQTLSKKE GEPLELTCET TKATVQHTHL SLTWYLMQEG GGSQATEIVS
210 220 230 240 250
LSKDFVLTPG SSYADRFVAG DVRLDKLGAT SFRLSVGKLQ PSDQGQVFCE
260 270 280 290 300
ATEWIQDPDE TWTLITRKQT DQTALRIQPA ARDFTVSITA SSSPDEGKPL
310 320 330 340 350
ELVCLAVGRD GNPQLQGVWF LNGKEIAQTD AGGVLDLKRD YRDRASQGQL
360 370 380 390 400
QVSKLSAQTF SLKIFSVGPE DVGTYSCEVA EVARTQMGSW QVLQRKQSPG
410 420 430 440 450
YRVQLREPAA RSVTVSAEQR TVWEGETLTL LCKAAGDVSA LSVSWWLTPQ
460 470 480 490 500
DQSTPVFVAG MGQDGTVQLG VSSPGPAHRG NRRLEKVDWA TFRLEIASAM
510 520 530 540 550
VTDSGTYECR VSERLQNQAK GLQSTQKISV TVKSLKSSLR VNLMSRQPQV
560 570 580 590 600
MLAHTFHLSC VVRANYSDLK LPFSVTWQFQ PAGSGAFHRL IRIAHNGTVE
610 620 630 640 650
WGDVLSQIHR KTKVSQSFFR SQLQIYDAAM EETGVYRCTV EVYDRDSICT
660 670 680 690 700
SGPARVSATS NLLMITVTFP ESKLSVNSSS QVQELSISSS TQIECAILSR
710 720 730 740 750
SAGNLPLSII WYFSSVSANA SYLKILEMDQ SSVVKYGDEF QTPRSKQKFY
760 770 780 790 800
SEKVSQDLFL LNILSVEDSD QGHYHCAVEE WLLSTNDTWQ KLERKTSGLT
810 820 830 840 850
ELKLRPTGSQ VHVSKVNWTG NATEYGEAGF SCSLDGSGST ASLYSVTWYR
860 870 880 890 900
GRGTATATAA AVANATATIT APAGSQMLVH LQYDGLLQYG REGSRRLQHC
910 920 930 940 950
YRSSPTDFVL KLHRVEMEDA GIYWCRVTEW QQHGHPGKWI NQASGESQRM
960 970 980 990 1000
VLRVLRSEPT VSSLICSSGP LLHFLIVCPF VMLLLLATSF LCLYRKARKL
1010 1020 1030
SQLSLSAKKE KALWVGMRKT SLQKEAGEES GHY
Length:1,033
Mass (Da):114,205
Last modified:November 13, 2007 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE0A0DD07DE0927C0
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0B4J1L8A0A0B4J1L8_MOUSE
Immunoglobulin superfamily member 2
Cd101
1,029Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural varianti175V → A in strain: NOD/MrkTac. 1
Natural varianti296E → K in strain: NOD/MrkTac. 1
Natural varianti318V → A in strain: NOD/MrkTac. 1
Natural varianti392V → I in strain: NOD/MrkTac. 1
Natural varianti451D → N in strain: NOD/MrkTac. 1
Natural varianti557H → D in strain: NOD/MrkTac. 1
Natural varianti565N → D in strain: NOD/MrkTac. 1
Natural varianti620R → H in strain: NOD/MrkTac. 1
Natural varianti648I → M in strain: NOD/MrkTac. 1
Natural varianti860A → T in strain: NOD/MrkTac. 1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AM849328 mRNA Translation: CAO94506.1
AM849329 mRNA Translation: CAO94507.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS51020.1

NCBI Reference Sequences

More...
RefSeqi
NP_001161378.1, NM_001167906.1

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Mm.190915

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000147399; ENSMUSP00000116643; ENSMUSG00000086564

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
630146

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:630146

UCSC genome browser

More...
UCSCi
uc012cuu.1 mouse

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM849328 mRNA Translation: CAO94506.1
AM849329 mRNA Translation: CAO94507.1
CCDSiCCDS51020.1
RefSeqiNP_001161378.1, NM_001167906.1
UniGeneiMm.190915

3D structure databases

ProteinModelPortaliA8E0Y8
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000116643

PTM databases

PhosphoSitePlusiA8E0Y8

Proteomic databases

MaxQBiA8E0Y8
PaxDbiA8E0Y8
PRIDEiA8E0Y8

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000147399; ENSMUSP00000116643; ENSMUSG00000086564
GeneIDi630146
KEGGimmu:630146
UCSCiuc012cuu.1 mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
9398
MGIiMGI:2685862 Cd101

Phylogenomic databases

eggNOGiENOG410IFBX Eukaryota
ENOG410YWQX LUCA
GeneTreeiENSGT00940000161722
HOGENOMiHOG000293322
HOVERGENiHBG107997
InParanoidiA8E0Y8
KOiK06522
OMAiQAVWEGE
OrthoDBi180654at2759
PhylomeDBiA8E0Y8
TreeFamiTF332702

Enzyme and pathway databases

ReactomeiR-MMU-202433 Generation of second messenger molecules

Miscellaneous databases

Protein Ontology

More...
PROi
PR:A8E0Y8

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000086564 Expressed in 14 organ(s), highest expression level in brain
ExpressionAtlasiA8E0Y8 baseline and differential

Family and domain databases

Gene3Di2.60.40.10, 7 hits
InterProiView protein in InterPro
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR003599 Ig_sub
IPR003598 Ig_sub2
IPR013106 Ig_V-set
IPR013151 Immunoglobulin
PfamiView protein in Pfam
PF00047 ig, 1 hit
PF07686 V-set, 3 hits
SMARTiView protein in SMART
SM00409 IG, 7 hits
SM00408 IGc2, 3 hits
SM00406 IGv, 5 hits
SUPFAMiSSF48726 SSF48726, 7 hits
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 7 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiIGSF2_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A8E0Y8
Secondary accession number(s): A8E0Y9
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 10, 2009
Last sequence update: November 13, 2007
Last modified: January 16, 2019
This is version 70 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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