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Entry version 86 (16 Oct 2019)
Sequence version 1 (13 Nov 2007)
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Protein

Thyroid adenoma-associated protein homolog

Gene

Thada

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Thyroid adenoma-associated protein homolog
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Thada
Synonyms:Kiaa1767
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 17

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:3039623 Thada

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003440581 – 1938Thyroid adenoma-associated protein homologAdd BLAST1938

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1006PhosphoserineCombined sources1
Modified residuei1015PhosphoserineBy similarity1
Modified residuei1152PhosphoserineBy similarity1

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
A8C756

MaxQB - The MaxQuant DataBase

More...
MaxQBi
A8C756

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
A8C756

PeptideAtlas

More...
PeptideAtlasi
A8C756

PRoteomics IDEntifications database

More...
PRIDEi
A8C756

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
A8C756

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
A8C756

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
A8C756

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000024251 Expressed in 192 organ(s), highest expression level in dorsal pancreas

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
A8C756 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
232178, 2 interactors

Protein interaction database and analysis system

More...
IntActi
A8C756, 1 interactor

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000041701

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili877 – 909Sequence analysisAdd BLAST33

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi943 – 946Poly-Leu4
Compositional biasi1313 – 1318Poly-Leu6
Compositional biasi1581 – 1584Poly-Leu4

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the THADA family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1810 Eukaryota
COG5543 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000015500

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000078273

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
A8C756

Identification of Orthologs from Complete Genome Data

More...
OMAi
FIIRCGR

Database of Orthologous Groups

More...
OrthoDBi
59905at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
A8C756

TreeFam database of animal gene trees

More...
TreeFami
TF319713

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR016024 ARM-type_fold
IPR019442 DUF2428_death-receptor-like

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF10350 DUF2428, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48371 SSF48371, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (5)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 5 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: A8C756-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MGVKKKREMQ VAALTVCHQD METLRSFADM EGKNLASLLL HCVQLTDGVS
60 70 80 90 100
QIHSIKQIVP LLEKVDKNGV CDPAIQSCLD ILAGIYFSLT LKNPLKKVLA
110 120 130 140 150
SSLNGLPEVF LTQATHSFTF HLQEELDTAD LYSYRKVMDN ISSCMENFNL
160 170 180 190 200
GRASVVNLLK DVLHFLQKSL IEILEENRKF AGNRIVQTQL MSDLLVGVRV
210 220 230 240 250
AMTLVQKVQG PQGSLWNDSS SPIWQSMCGL LSIFTKFLND DDLLQTVEST
260 270 280 290 300
SGLAVILFIK TMFRPSEKLP GLISSLLLRS AECTSIPEWL MNSCRSLCCT
310 320 330 340 350
DVPASTLLFL CQGTLAMLDW QDGSMGPSGE ALLLDIVHVL FTLSSQIKES
360 370 380 390 400
TLDMFLSRIL ASWTSSAIQI LESGSSGLKG HLNGDSCVPR RLLEYVYTHW
410 420 430 440 450
EHPLDALRHQ TKVMFRNLLQ MHRLTMEGAD LATDPFCLEL TKSLLQLEWH
460 470 480 490 500
IKGKYACLGC LVETLGIEHI LAIDKTIPSQ ILEVMGDQSL VPYASDLLET
510 520 530 540 550
MFKNHKSHLK SQTVTNTWMD KWHETWVFPV LSVLCGGNLD QRSYVIDYYL
560 570 580 590 600
PRILNYSPES LHYMVHILQA STDTGTGSCN HRGALGALMA CLRTARAHGH
610 620 630 640 650
LQSATQAWEN LVCSARVKQG LIHQHCQVRI DTLGLLCESN RSTEVVSTEE
660 670 680 690 700
MQWVQFFITY NLNSQSPGVR QQICSLLKKL FCRIQESSQV LYKLEQRKST
710 720 730 740 750
PDSENGSIRE QPSVTLQQYK NFMSSVCNIL FEALFPGSSY STRFSALTIL
760 770 780 790 800
GSVAEVFPDP EGNIQTVYQL SHDIDAGRYQ ILMECFTSTF EEVKTLAFDL
810 820 830 840 850
LMKLSSVTAG QFQDSEKLQD LFQAALELST STKPYDCVTA SYLLNLLIRQ
860 870 880 890 900
DALPAVLSAS SPQQLTRGAG ETSAVLERNT LVVIKCLMEN LEDEISQAEN
910 920 930 940 950
SLLQAASSFP MYGRVHCITR AFQRLPLNDL RLASEWRPLL GRLLLLSYRL
960 970 980 990 1000
STVVAPVIQS SSPEGLIPVD TDSASASRLQ LILNEIQPRD TNDYFNHTKI
1010 1020 1030 1040 1050
LKECDSFDLE DLSTSVSNID SSAEVKGKEE KACDVTAQMV LACCWRSMKE
1060 1070 1080 1090 1100
VALLLGTLCQ LLPVQPGPES SNVFLTVQQV KEIGDYFKQH LLQSRHRGAF
1110 1120 1130 1140 1150
ELAYTGFVKL TEILNRCSNV SLQKLPEQWL RSVLEEIKGS DPSSKLCATR
1160 1170 1180 1190 1200
RSAGIPFYIQ ALLASEPKKS RMDLLKITMR ELISLALSAD DSKGRVPQVH
1210 1220 1230 1240 1250
ALNILRALFR DTRLGENIIP YVAGGAKAAI LGFTSPVWAV RNSSTLLFSS
1260 1270 1280 1290 1300
LITRVFGVKR GKDEVSKTNR MTGREFFSRF PELYPFLLKQ LETVASTVDS
1310 1320 1330 1340 1350
ELGEPDRHPG MFLLLLVLER LYPSPMDGTS SALSLAPFVP FIIRCGRSPI
1360 1370 1380 1390 1400
YRSREMAARA LVPFIMIDQI PSTLCALLNS LPNSTDQCFR QNHIHGTLLQ
1410 1420 1430 1440 1450
VFHLLQAYIT DCRHRTNADF LQELSDVTAC TKAKLWLAMR QNPCLVTRAV
1460 1470 1480 1490 1500
YIDILFLLTN CLDRPEEGKQ TALESLGFWE DVRRIILESE LIKGFPWTFK
1510 1520 1530 1540 1550
VPGLPQYLQS LTKLAIPEVW ASLAEAKGQA TAVPLSFSRL LKSSFPEVRL
1560 1570 1580 1590 1600
LALDTLLERA RSSEQEQKEP LPLLCSMGEE LLLLAMKEDH PGCFCRVLKI
1610 1620 1630 1640 1650
LYHLNPSEWL PQTECYAHLS PKEFLMWSMD IASNDRSEIQ GVALKLASKI
1660 1670 1680 1690 1700
IAYRVQSCEK NKDSLAPELR QWVQLVVWSC GDHLPTASRL AVAEVLTSTA
1710 1720 1730 1740 1750
PLFLTSPQPI LELQGTLSLW RCVLTLLQSE EQTVREAATE IVTTAMSQGN
1760 1770 1780 1790 1800
TCQSTEFAFC QVDASIALTL ALAVLCDLLQ QWDQLEPGLP ILLGWLLEEG
1810 1820 1830 1840 1850
DDLEGHVQSP HQGEEEHIFE KSEVNFWAET LTFVKSLCRQ LFHLLCQSGW
1860 1870 1880 1890 1900
QSPHSQKLCH LQRIASEQSH LISQLFRELP LSAEFLKTVE YTRLRIQEER
1910 1920 1930
TLAVLRLLAC LEGKEGLRAE DCPREWRQVM APRTEAAC
Length:1,938
Mass (Da):217,289
Last modified:November 13, 2007 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF1E09CC95E2A2B54
GO
Isoform 2 (identifier: A8C756-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-1270: Missing.

Show »
Length:668
Mass (Da):75,674
Checksum:iB2AC92D667ECE12D
GO
Isoform 3 (identifier: A8C756-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-1438: Missing.

Note: No experimental confirmation available.
Show »
Length:500
Mass (Da):56,646
Checksum:i78F416E93E0D8E18
GO
Isoform 4 (identifier: A8C756-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     347-347: I → V
     348-1938: Missing.

Note: No experimental confirmation available.
Show »
Length:347
Mass (Da):38,376
Checksum:i6A769CB239E9B999
GO
Isoform 5 (identifier: A8C756-5) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-1576: Missing.

Note: No experimental confirmation available.
Show »
Length:362
Mass (Da):41,036
Checksum:i5A19E8B8FAFFBF9C
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAD32536 differs from that shown. Intron retention.Curated
The sequence BAE33129 differs from that shown. Reason: Erroneous termination. Truncated C-terminus.Curated
The sequence BAE41536 differs from that shown. Reason: Frameshift.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti1749G → V in BAE33129 (PubMed:16141072).Curated1
Sequence conflicti1750N → S in AAH52885 (PubMed:15489334).Curated1
Sequence conflicti1759F → S in BAE33129 (PubMed:16141072).Curated1
Sequence conflicti1925E → G in BAE33129 (PubMed:16141072).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0347401 – 1576Missing in isoform 5. 1 PublicationAdd BLAST1576
Alternative sequenceiVSP_0347361 – 1438Missing in isoform 3. 1 PublicationAdd BLAST1438
Alternative sequenceiVSP_0347371 – 1270Missing in isoform 2. 1 PublicationAdd BLAST1270
Alternative sequenceiVSP_034738347I → V in isoform 4. 1 Publication1
Alternative sequenceiVSP_034739348 – 1938Missing in isoform 4. 1 PublicationAdd BLAST1591

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
EF222207 mRNA Translation: ABQ10601.1
AK044550 mRNA Translation: BAC31976.1
AK155218 mRNA Translation: BAE33129.1 Sequence problems.
AK170056 mRNA Translation: BAE41536.1 Frameshift.
BC052885 mRNA Translation: AAH52885.1
AK173258 mRNA Translation: BAD32536.1 Sequence problems.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS50198.1 [A8C756-1]

NCBI Reference Sequences

More...
RefSeqi
NP_898842.2, NM_183021.3 [A8C756-1]
XP_006524337.2, XM_006524274.3 [A8C756-1]
XP_006524339.1, XM_006524276.3 [A8C756-1]
XP_017172962.1, XM_017317473.1 [A8C756-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000047524; ENSMUSP00000041701; ENSMUSG00000024251 [A8C756-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
240174

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:240174

UCSC genome browser

More...
UCSCi
uc008dsr.2 mouse [A8C756-3]
uc008dss.2 mouse [A8C756-2]
uc012axy.1 mouse [A8C756-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF222207 mRNA Translation: ABQ10601.1
AK044550 mRNA Translation: BAC31976.1
AK155218 mRNA Translation: BAE33129.1 Sequence problems.
AK170056 mRNA Translation: BAE41536.1 Frameshift.
BC052885 mRNA Translation: AAH52885.1
AK173258 mRNA Translation: BAD32536.1 Sequence problems.
CCDSiCCDS50198.1 [A8C756-1]
RefSeqiNP_898842.2, NM_183021.3 [A8C756-1]
XP_006524337.2, XM_006524274.3 [A8C756-1]
XP_006524339.1, XM_006524276.3 [A8C756-1]
XP_017172962.1, XM_017317473.1 [A8C756-1]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi232178, 2 interactors
IntActiA8C756, 1 interactor
STRINGi10090.ENSMUSP00000041701

PTM databases

iPTMnetiA8C756
PhosphoSitePlusiA8C756
SwissPalmiA8C756

Proteomic databases

EPDiA8C756
MaxQBiA8C756
PaxDbiA8C756
PeptideAtlasiA8C756
PRIDEiA8C756

Genome annotation databases

EnsembliENSMUST00000047524; ENSMUSP00000041701; ENSMUSG00000024251 [A8C756-1]
GeneIDi240174
KEGGimmu:240174
UCSCiuc008dsr.2 mouse [A8C756-3]
uc008dss.2 mouse [A8C756-2]
uc012axy.1 mouse [A8C756-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
63892
MGIiMGI:3039623 Thada

Rodent Unidentified Gene-Encoded large proteins database

More...
Rougei
Search...

Phylogenomic databases

eggNOGiKOG1810 Eukaryota
COG5543 LUCA
GeneTreeiENSGT00390000015500
HOGENOMiHOG000078273
InParanoidiA8C756
OMAiFIIRCGR
OrthoDBi59905at2759
PhylomeDBiA8C756
TreeFamiTF319713

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Thada mouse

Protein Ontology

More...
PROi
PR:A8C756

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000024251 Expressed in 192 organ(s), highest expression level in dorsal pancreas
GenevisibleiA8C756 MM

Family and domain databases

InterProiView protein in InterPro
IPR016024 ARM-type_fold
IPR019442 DUF2428_death-receptor-like
PfamiView protein in Pfam
PF10350 DUF2428, 1 hit
SUPFAMiSSF48371 SSF48371, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTHADA_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A8C756
Secondary accession number(s): Q3TDR4
, Q3U2L1, Q69ZA8, Q7TPV7, Q8C8S7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 22, 2008
Last sequence update: November 13, 2007
Last modified: October 16, 2019
This is version 86 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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