Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 48 (10 Apr 2019)
Sequence version 1 (13 Nov 2007)
Previous versions | rss
Other tutorials and videosHelp videoFeedback
Protein
Submitted name:

Transcription regulatory protein SNF2

Gene

GL50803_16143

Organism
Giardia intestinalis (strain ATCC 50803 / WB clone C6) (Giardia lamblia)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Transcription regulatory protein SNF2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:GL50803_16143Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiGiardia intestinalis (strain ATCC 50803 / WB clone C6) (Giardia lamblia)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri184922 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaDiplomonadidaHexamitidaeGiardiinaeGiardia
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
GiardiaDB:GL50803_16143

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
A8B3K5

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini531 – 740Helicase ATP-bindingInterPro annotationAdd BLAST210
Domaini1099 – 1250Helicase C-terminalInterPro annotationAdd BLAST152
Domaini1886 – 1948BromoInterPro annotationAdd BLAST63

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

BromodomainPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0386 Eukaryota
COG0553 LUCA

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
A8B3K5

KEGG Orthology (KO)

More...
KOi
K11647

Identification of Orthologs from Complete Genome Data

More...
OMAi
INCRFRI

Database of Orthologous Groups

More...
OrthoDBi
27281at2759

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00079 HELICc, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.920.10, 1 hit
3.40.50.10810, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001487 Bromodomain
IPR036427 Bromodomain-like_sf
IPR014001 Helicase_ATP-bd
IPR001650 Helicase_C
IPR027417 P-loop_NTPase
IPR038718 SNF2-like_sf
IPR000330 SNF2_N

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00439 Bromodomain, 1 hit
PF00271 Helicase_C, 1 hit
PF00176 SNF2_N, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00297 BROMO, 1 hit
SM00487 DEXDc, 1 hit
SM00490 HELICc, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47370 SSF47370, 1 hit
SSF52540 SSF52540, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50014 BROMODOMAIN_2, 1 hit
PS51192 HELICASE_ATP_BIND_1, 1 hit
PS51194 HELICASE_CTER, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A8B3K5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKTSLADLLR KPLLRHAFDP HERGSNLSGD RDRQGTVDHG QNHAHCVQTH
60 70 80 90 100
HSSPSSASGE CIKMEPAQSH KNQVDPEDRL QPRSDGPKPP QSQEAGVCLT
110 120 130 140 150
YQLPYLSFGK RMIKVFPNLN ITNAHREFMV LYEFDYRLTE FSLITYLTQK
160 170 180 190 200
RRAFLSEVDL YAETDLGSPE DVEASQYLIL ANLISRPRLR GFYRPLNSYY
210 220 230 240 250
AVNCLLYHDP QPAKTLKTSF LQSLQQQSLL NMRFAAEKRE MAATLKQKML
260 270 280 290 300
SLTTGNFKLS IVCRHESPLI GKIFGSGLQK YMLPRSQILT TTGKQGSSGV
310 320 330 340 350
NKYSNLPDFA FKTYTDDMIN SLIYMYLRQF ENVYTLEDAR QKRIFLPPVF
360 370 380 390 400
LTLLLEITRY ELHVMSRLGV DPTVTLETTT NRSTVEAHEI SAMLDSILAR
410 420 430 440 450
TNPSDIDPAC TVNYSYLFKT DSFAESGSAE AQEALETLIE SHPGFTERHK
460 470 480 490 500
ALLYQAELGL KLIEYILKNT GYENNLHFEQ RLYDQVHIQY PIELTTQPVS
510 520 530 540 550
IQHGRLKNYQ LDGVKFLVSL YRSSNANLQD LQTGTGSSGC LLADDMGCGK
560 570 580 590 600
TAQSIAFLAY LSDNRISTGM HLIISPLAVS DSWATEFQTW FPNFSILLYK
610 620 630 640 650
GDQEQRAKYR RHILTLSKGN ISVLTDYGGP AIKDKDSRTA SGSAGYSSGD
660 670 680 690 700
SGKSTNQILS NINAIVTTYE YAIKDRSFFR QIDFDVVIVD EASRVKNARG
710 720 730 740 750
KLIDVLKKSI NCRFRILLSG TPIQNNLREL FTLLGLIHPA VFCDYDRFES
760 770 780 790 800
IFGQVFSLAH TGRNSDLHHA HHGYHGFRRR ASTDSAQLEV SDMRTGASPS
810 820 830 840 850
LSSVQMQSMQ SISTTTSQAV GRRSKRQCGS TAVTFADDLG EDELDSSYSY
860 870 880 890 900
SNKDSSEDEN DNDSELSRVS SVPTEMMVPI GSTASLIGAK TASSLPELTQ
910 920 930 940 950
DLPQNAPITK DNIAEVAIQL AENIDKISGL TNSQKTFIVE RLHGILKPFL
960 970 980 990 1000
LRRVKTEVLA QLPPKEEIII RVPLSAFQLF FYNLAIANGR AMTNPDLASS
1010 1020 1030 1040 1050
LPANFIRNLD IYLRCVCNHP FTALEHDKLQ LLYNFYLMKA KSFSARHKAE
1060 1070 1080 1090 1100
NTDFYRQYGG AKEEASKDAT ASMPPNNFNV LENMYVNDQI WRVSGKLELL
1110 1120 1130 1140 1150
DNILAKLHKT SHRVLIFSQF KKVLDVLSSY LHYRQYKFVR FDGSVKDVDR
1160 1170 1180 1190 1200
NSMIRGYNRE DSKDFVFLLS TRAASHGLNL QTADTVIIFD CDYNGTYDQQ
1210 1220 1230 1240 1250
AQDRCYRLGQ VNPVKVFKLY SNTAIESKML SVATSKLSLA TIVMDAGTYT
1260 1270 1280 1290 1300
TNAGDKTDGT AGATVTGGGA RKKTKMSTQE YILEVLSANS VVPDDVHIPT
1310 1320 1330 1340 1350
SEEINRYLAR NDMEFQAFQM HDIETSLYWR KRNFDEDVPR LDPEIPSVFS
1360 1370 1380 1390 1400
EQKDQIYEEM REMNLLEDKQ EVVMPNMQIP SAESGGKRSH SAGADSNSTT
1410 1420 1430 1440 1450
SDYDEDDSLD EGLLASETDT GGSQQRKLVP KVLKKTQSIK KSMSRSLTAQ
1460 1470 1480 1490 1500
DLSESAVFSL CMQVDKSLRD DPAFRNSIVL SSTIIQKTSV VLTPVVDTPI
1510 1520 1530 1540 1550
ACFLIDHGHS SGVLFLVSTM VGMADLLRRE DAYNNLGACV TQYVSSNLSS
1560 1570 1580 1590 1600
LFACFSRQSL VKQSAESVSL AQHLSSLVMA PGFSSPGNAG SGSWDSYLFL
1610 1620 1630 1640 1650
TGSESILQTA YTFPLAQQGH PLSTYQLLFT KAALFIMALK LERDVFHNDL
1660 1670 1680 1690 1700
LSYLTTDLTN AKKYTGISYS SLLFYFSSGL AVAVEEQSLC APDLLYSKPS
1710 1720 1730 1740 1750
SESAVLNESA DTTSLFLRSD RAYTDVYIKL ESLPQLSGDI DVIRRGYAWY
1760 1770 1780 1790 1800
NGLSQSQRDQ QPSYLQYLCN VIDHCRVGAA SQDQLDPLPI YVRITTNTER
1810 1820 1830 1840 1850
LRYLYSSARS SGVTTDVLRL LYATVSFHLR IMAIFNYLIH LIDPLCAHPS
1860 1870 1880 1890 1900
EDSVDVSSTV AGDSEPESGK EDSSKALLTY RILSQFWILP SKTELPSYYH
1910 1920 1930 1940 1950
AIPYPRSLAY IYYKLITLSY LSLHEFVADM RQSFKNCLQF NERSSAFCEH
1960 1970 1980 1990 2000
AKVCNELTFQ QISQHFQYCN ASSVISWFTA YERRLSVVKK GYTLLSTFVG
2010 2020 2030 2040 2050
CGIYELLSLP ITEGPGPFHL EMDGEKCKGL ILSYGSGADM AGLCAYDILR
2060 2070
YAIAAAKEGE SGTGSTVTYP DASVRHVKK
Length:2,079
Mass (Da):232,692
Last modified:November 13, 2007 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i9B88E130C3432FB7
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AACB02000001 Genomic DNA Translation: EDO82571.1

NCBI Reference Sequences

More...
RefSeqi
XP_001710245.1, XM_001710193.1

Genome annotation databases

Ensembl protists genome annotation project

More...
EnsemblProtistsi
EDO82571; EDO82571; GL50803_16143

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
5703174

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
gla:GL50803_16143

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACB02000001 Genomic DNA Translation: EDO82571.1
RefSeqiXP_001710245.1, XM_001710193.1

3D structure databases

ProteinModelPortaliA8B3K5
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiEDO82571; EDO82571; GL50803_16143
GeneIDi5703174
KEGGigla:GL50803_16143

Organism-specific databases

EuPathDBiGiardiaDB:GL50803_16143

Phylogenomic databases

eggNOGiKOG0386 Eukaryota
COG0553 LUCA
InParanoidiA8B3K5
KOiK11647
OMAiINCRFRI
OrthoDBi27281at2759

Family and domain databases

CDDicd00079 HELICc, 1 hit
Gene3Di1.20.920.10, 1 hit
3.40.50.10810, 2 hits
InterProiView protein in InterPro
IPR001487 Bromodomain
IPR036427 Bromodomain-like_sf
IPR014001 Helicase_ATP-bd
IPR001650 Helicase_C
IPR027417 P-loop_NTPase
IPR038718 SNF2-like_sf
IPR000330 SNF2_N
PfamiView protein in Pfam
PF00439 Bromodomain, 1 hit
PF00271 Helicase_C, 1 hit
PF00176 SNF2_N, 2 hits
SMARTiView protein in SMART
SM00297 BROMO, 1 hit
SM00487 DEXDc, 1 hit
SM00490 HELICc, 1 hit
SUPFAMiSSF47370 SSF47370, 1 hit
SSF52540 SSF52540, 2 hits
PROSITEiView protein in PROSITE
PS50014 BROMODOMAIN_2, 1 hit
PS51192 HELICASE_ATP_BIND_1, 1 hit
PS51194 HELICASE_CTER, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA8B3K5_GIAIC
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A8B3K5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 13, 2007
Last sequence update: November 13, 2007
Last modified: April 10, 2019
This is version 48 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again