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UniProtKB - A7ZHX6 (A7ZHX6_ECO24)

Entry version 66 (07 Oct 2020)
Sequence version 1 (23 Oct 2007)
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Protein
Submitted name:

Rhs protein

Gene

EcE24377A_0246

Organism
Escherichia coli O139:H28 (strain E24377A / ETEC)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Rhs proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:EcE24377A_0246Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEscherichia coli O139:H28 (strain E24377A / ETEC)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri331111 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001122 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni493 – 529DisorderedSequence analysisAdd BLAST37

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi496 – 510PolyampholyteSequence analysisAdd BLAST15

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the RHS family.ARBA annotation

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_001218_0_1_6

Identification of Orthologs from Complete Genome Data

More...OMAi		YHYDLTR

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR001826, RHS
IPR022385, Rhs_assc_core
IPR031325, RHS_repeat
IPR006530, YD

Pfam protein domain database

More...Pfami		View protein in Pfam
PF03527, RHS, 1 hit
PF05593, RHS_repeat, 5 hits

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR00394, RHSPROTEIN

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR03696, Rhs_assc_core, 1 hit
TIGR01643, YD_repeat_2x, 7 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A7ZHX6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGGKPAARQG DMTRKGLDIV QGSAGVLIGA PTGVACSVCP NSPIEEQKGN 
        60         70         80         90        100
PVNPLLGAKV LPGETDLALP CPLPFILSRA YSSYRTRTPA PVGVFGPGWK 
       110        120        130        140        150
APFDIRLQVH ERELILNDSG GRSIHFEPLF PGEISYSRSE SLWLARGGVA 
       160        170        180        190        200
AQHSSQPLSA LWQVLPEDVR LSPHVYLATN SLQGPWWILS WPERVPGADE 
       210        220        230        240        250
VLPPEPPAYR VLTGVVDGFG RTLAFHRAAE GDVAGAVTGV TDGAGRRFHL 
       260        270        280        290        300
VLTTQAQRAE VFRKQRATSL SSPAGPRSAS SSLVFPDTLP AGTGYGTDNG 
       310        320        330        340        350
IRLEAVWLTH DPAYPDEQPT APLARYTYTA GGELRAVYDR SGTQVRGFTY 
       360        370        380        390        400
DAEHAGRMVA HHYAGRPESC YRYDDTGRVT EQVNPEGLDY RFEYGESRVI 
       410        420        430        440        450
ITDSLNRREV LYTEGEGGLK RVVKKEHADG SITRSEYDEA GRLKAQTDAA 
       460        470        480        490        500
GRRTEYSLHM ASGAVTAVTG PDGRTVRYGY NSQRQVTSVT YPDGLRSSRE 
       510        520        530        540        550
YDEKGRLTAE TSRSGETTRY SYDDPASELP TGIQDAMGST KQMAWSRYGQ 
       560        570        580        590        600
LLAFTDCSGY TTRYEYDRYG QQIAVHREEG ISTYSSYNPR GQMVSQKDAQ 
       610        620        630        640        650
GRETPYEYSA AGDLTATVSP DGKRSTIAYD KRGRPVSVTE GGLTRSMGYD 
       660        670        680        690        700
AAGRITVLTN ENGSQSTFRY DPVDRLTEQR GFDGRTQRYH YDLTRKLTQS 
       710        720        730        740        750
EDEGLITLWH YDASDRITHR TVNGDPAEQW QYDEHGWLTT LSHTSEGHRV 
       760        770        780        790        800
SVHYGYDDKG RLTGERQTVE NPETGELLWQ HETKHAYNEQ GLANRVTPDS 
       810        820        830        840        850
LPPVEWLTYG SGYLAGMKLG GTPLVEYTRD RLHRETVRSF GSRAGSNAAY 
       860        870        880        890        900
ELTSTYTPAG QLQSQHLNSL VYDRDYGWND NGDLVRISGP RQTREYGYSA 
       910        920        930        940        950
TGRLESVRTL APDLDIRIPY ATDPAGNRLP DPELHPDSTL TAWPDNRIAE 
       960        970        980        990       1000
DAHYVYHYDE YGRLTEKTDR IPTGVIRTDD ERTHHYHYDS QHRLVFHTRI 
      1010       1020       1030       1040       1050
QHGEPLVESR YLYDPLGRRM AKRVWRRERD LTGWMSLSRK PEETWYGWDG 
      1060       1070       1080       1090       1100
DRLTTVQTDT TRIQTVYQPG SFAPLIRIET DNGEREKAQC RSLAEKIQQE 
      1110       1120       1130       1140       1150
GSEDGHGVVF PAELVGLLDR LEGEIRANCV SSESRQWLAQ CGLTVERLAA 
      1160       1170       1180       1190       1200
QIEPVYLPER KIHLYHCDHR GLPLALISED GNTAWSAEYD EWGNQLNEEN 
      1210       1220       1230       1240       1250
PHHLHQPYRM PGQQYDKESG LYYNRHRYYD PLQGRYITPD PIGLRGGWNM 
      1260       1270       1280       1290       1300
YQYPLNPIQV IDPMGLDAIE NMTSGGLIYA VSGVPGLIAA NSITNSAYQF 
      1310       1320       1330       1340       1350
GYDMDAIVGG AHNGAADAMR HCYLMCRMTK TFGSTIADVI GKNHEAAGDR 
      1360       1370       1380       1390       1400
QGQPAKERIM DLKNNTVGIA CGDFSAKCSD ACIEKYNTGQ LFGLDGIKAD 
      1410 
NPIKAKQGSS DASNY
Length:1,415
Mass (Da):157,658
Last modified:October 23, 2007 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i90AEFC2DAC239C8D
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
CP000800 Genomic DNA Translation: ABV20272.1

NCBI Reference Sequences

More...RefSeqi		WP_000509144.1, NC_009801.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...EnsemblBacteriai		ABV20272; ABV20272; EcE24377A_0246

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		ecw:EcE24377A_0246

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000800 Genomic DNA Translation: ABV20272.1
RefSeqiWP_000509144.1, NC_009801.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Genome annotation databases

EnsemblBacteriaiABV20272; ABV20272; EcE24377A_0246
KEGGiecw:EcE24377A_0246

Phylogenomic databases

HOGENOMiCLU_001218_0_1_6
OMAiYHYDLTR

Family and domain databases

InterProiView protein in InterPro
IPR001826, RHS
IPR022385, Rhs_assc_core
IPR031325, RHS_repeat
IPR006530, YD
PfamiView protein in Pfam
PF03527, RHS, 1 hit
PF05593, RHS_repeat, 5 hits
PRINTSiPR00394, RHSPROTEIN
TIGRFAMsiTIGR03696, Rhs_assc_core, 1 hit
TIGR01643, YD_repeat_2x, 7 hits

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA7ZHX6_ECO24
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A7ZHX6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 23, 2007
Last sequence update: October 23, 2007
Last modified: October 7, 2020
This is version 66 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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