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Protein

Probable molybdenum cofactor guanylyltransferase

Gene

mobA

Organism
Bacillus velezensis (strain DSM 23117 / BGSC 10A6 / FZB42) (Bacillus amyloliquefaciens subsp. plantarum)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.UniRule annotation

Catalytic activityi

GTP + molybdenum cofactor = diphosphate + guanylyl molybdenum cofactor.UniRule annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei20GTPUniRule annotation1
Binding sitei66GTPUniRule annotation1
Metal bindingi97MagnesiumUniRule annotation1
Binding sitei97GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi8 – 10GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferase
Biological processMolybdenum cofactor biosynthesis
LigandGTP-binding, Magnesium, Metal-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBAMY326423:G1G84-1429-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable molybdenum cofactor guanylyltransferaseUniRule annotation (EC:2.7.7.77UniRule annotation)
Short name:
MoCo guanylyltransferaseUniRule annotation
Alternative name(s):
GTP:molybdopterin guanylyltransferaseUniRule annotation
Mo-MPT guanylyltransferaseUniRule annotation
Molybdopterin guanylyltransferaseUniRule annotation
Molybdopterin-guanine dinucleotide synthaseUniRule annotation
Short name:
MGD synthaseUniRule annotation
Gene namesi
Name:mobAUniRule annotation
Ordered Locus Names:RBAM_014020
OrganismiBacillus velezensis (strain DSM 23117 / BGSC 10A6 / FZB42) (Bacillus amyloliquefaciens subsp. plantarum)
Taxonomic identifieri326423 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus amyloliquefaciens group
Proteomesi
  • UP000001120 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001157881 – 200Probable molybdenum cofactor guanylyltransferaseAdd BLAST200

Structurei

3D structure databases

ProteinModelPortaliA7Z439.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domaini

The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.UniRule annotation

Sequence similaritiesi

Belongs to the MobA family.UniRule annotation

Phylogenomic databases

eggNOGiENOG41082CS. Bacteria.
COG0746. LUCA.
HOGENOMiHOG000280425.
KOiK03752.
OMAiSVCYVQA.

Family and domain databases

CDDicd02503. MobA. 1 hit.
Gene3Di3.90.550.10. 1 hit.
HAMAPiMF_00316. MobA. 1 hit.
InterProiView protein in InterPro
IPR025877. MobA-like_NTP_Trfase.
IPR013482. Molybde_CF_guanTrfase.
IPR029044. Nucleotide-diphossugar_trans.
PfamiView protein in Pfam
PF12804. NTP_transf_3. 1 hit.
SUPFAMiSSF53448. SSF53448. 1 hit.

Sequencei

Sequence statusi: Complete.

A7Z439-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKRVNVILAG GASRRFGEPK AFAKWKGGMF YEQAKKAFGG GETVIISRPE
60 70 80 90 100
HIKKFLSNRE RHVLADEPRF RGMGPLAGIY TAMKQTEGET FTVISCDTPL
110 120 130 140 150
VTRKTMVALE MKLTGNLDAV IPVCKNREQP LLAVYHKRVQ DVLFDQLTQN
160 170 180 190 200
KLKMTDTLKR LSVCYVQAED IGAGPEEFAN INTQDDYTRL LAHVESSNQD
Length:200
Mass (Da):22,451
Last modified:October 23, 2007 - v1
Checksum:i3257E8783B2CC2E9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000560 Genomic DNA. Translation: ABS73765.1.
RefSeqiWP_012117449.1. NC_009725.1.

Genome annotation databases

EnsemblBacteriaiABS73765; ABS73765; RBAM_014020.
KEGGibay:RBAM_014020.

Similar proteinsi

Entry informationi

Entry nameiMOBA_BACVZ
AccessioniPrimary (citable) accession number: A7Z439
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: October 23, 2007
Last modified: March 28, 2018
This is version 65 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome