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Protein

Transaldolase

Gene

tal

Organism
Vibrio campbellii (strain ATCC BAA-1116 / BB120)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.UniRule annotation

Catalytic activityi

Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate.UniRule annotation

Pathwayi: pentose phosphate pathway

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage).UniRule annotation
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Transaldolase (tal)
  3. no protein annotated in this organism
This subpathway is part of the pathway pentose phosphate pathway, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage), the pathway pentose phosphate pathway and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei132Schiff-base intermediate with substrateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferase
Biological processPentose shunt
LigandSchiff base

Enzyme and pathway databases

UniPathwayiUPA00115; UER00414

Names & Taxonomyi

Protein namesi
Recommended name:
TransaldolaseUniRule annotation (EC:2.2.1.2UniRule annotation)
Gene namesi
Name:talUniRule annotation
Ordered Locus Names:VIBHAR_06256
OrganismiVibrio campbellii (strain ATCC BAA-1116 / BB120)
Taxonomic identifieri338187 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
Proteomesi
  • UP000008152 Componenti: Chromosome II

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000145331 – 316TransaldolaseAdd BLAST316

Interactioni

Subunit structurei

Homodimer.By similarity

Protein-protein interaction databases

STRINGi338187.VIBHAR_06256

Structurei

3D structure databases

ProteinModelPortaliA7N1Z7
SMRiA7N1Z7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the transaldolase family. Type 1 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CW3 Bacteria
COG0176 LUCA
HOGENOMiHOG000281234
KOiK00616
OMAiMAFDKLH

Family and domain databases

CDDicd00957 Transaldolase_TalAB, 1 hit
Gene3Di3.20.20.70, 1 hit
HAMAPiMF_00492 Transaldolase_1, 1 hit
InterProiView protein in InterPro
IPR013785 Aldolase_TIM
IPR001585 TAL/FSA
IPR004730 Transaldolase_1
IPR018225 Transaldolase_AS
PANTHERiPTHR10683 PTHR10683, 1 hit
PTHR10683:SF20 PTHR10683:SF20, 1 hit
PfamiView protein in Pfam
PF00923 TAL_FSA, 1 hit
TIGRFAMsiTIGR00874 talAB, 1 hit
PROSITEiView protein in PROSITE
PS01054 TRANSALDOLASE_1, 1 hit
PS00958 TRANSALDOLASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

A7N1Z7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSNKLEQLRK LTTVVADTGE IDAIKKYQPE DATTNPSLIL KAAQIEEYAP
60 70 80 90 100
LIDASIEYAK AQSNDKAQQV QDTCDMLAVN IGKEILKTIP GRISTEVDAR
110 120 130 140 150
LSYDTEGSVA KARQLVKMYN DAGITNDRIL IKLASTWEGI RAAEILEKEG
160 170 180 190 200
INCNLTLLFS FAQARACAEA GVFLISPFVG RIMDWYKAKE GRDFEASEDP
210 220 230 240 250
GVISVTDIYN YYKDYGYNTV VMGASFRNIG EILELAGCDR LTIAPALLAE
260 270 280 290 300
LEAAEGEVVE KLVDSKGSKE RPAPMSHAEF LWEHNLDAMA VEKVAEGIRN
310
FAVDQGKLED MIAAKL
Length:316
Mass (Da):34,783
Last modified:October 2, 2007 - v1
Checksum:iEFE465AD642D7945
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000790 Genomic DNA Translation: ABU74148.1
RefSeqiWP_005425862.1, NC_022270.1

Genome annotation databases

EnsemblBacteriaiABU74148; ABU74148; VIBHAR_06256
GeneIDi5558354
KEGGivca:M892_20780
vha:VIBHAR_06256
PATRICifig|338187.25.peg.4084

Similar proteinsi

Entry informationi

Entry nameiTAL_VIBCB
AccessioniPrimary (citable) accession number: A7N1Z7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 2, 2007
Last modified: December 20, 2017
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

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