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Protein

Altronate oxidoreductase

Gene

uxaB

Organism
Cronobacter sakazakii (strain ATCC BAA-894) (Enterobacter sakazakii)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-altronate + NAD+ = D-tagaturonate + NADH.UniRule annotation

Pathwayi: pentose and glucuronate interconversion

This protein is involved in the pathway pentose and glucuronate interconversion, which is part of Carbohydrate metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway pentose and glucuronate interconversion and in Carbohydrate metabolism.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi18 – 29NADUniRule annotationAdd BLAST12

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductase
LigandNAD

Enzyme and pathway databases

BioCyciCSAK290339:G1G9O-1729-MONOMER
UniPathwayiUPA00246

Names & Taxonomyi

Protein namesi
Recommended name:
Altronate oxidoreductaseUniRule annotation (EC:1.1.1.58UniRule annotation)
Alternative name(s):
Tagaturonate dehydrogenaseUniRule annotation
Tagaturonate reductaseUniRule annotation
Gene namesi
Name:uxaBUniRule annotation
Ordered Locus Names:ESA_01824
OrganismiCronobacter sakazakii (strain ATCC BAA-894) (Enterobacter sakazakii)
Taxonomic identifieri290339 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeCronobacter
Proteomesi
  • UP000000260 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000447051 – 483Altronate oxidoreductaseAdd BLAST483

Interactioni

Protein-protein interaction databases

STRINGi290339.ESA_01824

Structurei

3D structure databases

ProteinModelPortaliA7MPR2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the mannitol dehydrogenase family. UxaB subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107QZW Bacteria
COG0246 LUCA
HOGENOMiHOG000029586
KOiK00041
OMAiVVIVRPI

Family and domain databases

Gene3Di1.10.1040.10, 1 hit
HAMAPiMF_00670 Altron_oxidoreduct, 1 hit
InterProiView protein in InterPro
IPR008927 6-PGluconate_DH-like_C_sf
IPR013328 6PGD_dom2
IPR023668 Altronate_OxRdtase
IPR013118 Mannitol_DH_C
IPR013131 Mannitol_DH_N
IPR036291 NAD(P)-bd_dom_sf
PfamiView protein in Pfam
PF01232 Mannitol_dh, 1 hit
PF08125 Mannitol_dh_C, 1 hit
SUPFAMiSSF48179 SSF48179, 1 hit
SSF51735 SSF51735, 1 hit

Sequencei

Sequence statusi: Complete.

A7MPR2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTLNRRDFP GALWPERIIQ FGEGNFLRAF IDWQVDLLNE HTDLNAGVVV
60 70 80 90 100
VRPIASDFPP SLSTQDGLYT TIIRGLNEKG EAVSESRLIR SVNREISVYA
110 120 130 140 150
QYDEFLKLAH NPDIRFVFSN TTEAGISYHA GDQFDDAPAV SYPAKLTRLL
160 170 180 190 200
FERFSHFDGA QDKGWVIIPC ELIDYNGEAL RELVLRYAHE WALPAAFTTW
210 220 230 240 250
LESANSFCST LVDRIVTGYP RDEVAQLEES LGYHDAFLDT AEHFYLFVIQ
260 270 280 290 300
GPQWLARELR LDKLPLNVLI VDDIKPYKAR KVAILNGAHT ALVPVAFLAG
310 320 330 340 350
LNTVGEAMND AQICAFVERA IHDEIIPVLD LPRNELESFA DAVVSRFRNP
360 370 380 390 400
YIKHQLLSIA LNGMTKFRTR ILPQLLAGQA QMGTLPPRLT FALAALIAFY
410 420 430 440 450
RGERNGEGYP LQDDAHWLAR FEQLWTQRGD NTITLRELVD AVLSDCEHWE
460 470 480
QDLTAVPGLA AQVTRDLDAI LNQGMRHAVA PLC
Length:483
Mass (Da):54,430
Last modified:October 2, 2007 - v1
Checksum:i290D81D64C61243C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000783 Genomic DNA Translation: ABU77078.1
RefSeqiWP_012124768.1, NC_009778.1

Genome annotation databases

EnsemblBacteriaiABU77078; ABU77078; ESA_01824
KEGGiesa:ESA_01824
PATRICifig|290339.8.peg.1626

Similar proteinsi

Entry informationi

Entry nameiUXAB_CROS8
AccessioniPrimary (citable) accession number: A7MPR2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 2, 2007
Last modified: July 18, 2018
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

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