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Protein

Ribosomal RNA small subunit methyltransferase B

Gene

rsmB

Organism
Cronobacter sakazakii (strain ATCC BAA-894) (Enterobacter sakazakii)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + cytosine(967) in 16S rRNA = S-adenosyl-L-homocysteine + 5-methylcytosine(967) in 16S rRNA.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei277S-adenosyl-L-methionineUniRule annotation1
Binding sitei303S-adenosyl-L-methionineUniRule annotation1
Binding sitei322S-adenosyl-L-methionineUniRule annotation1
Active sitei375NucleophileUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMethyltransferase, RNA-binding, Transferase
Biological processrRNA processing
LigandS-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciCSAK290339:G1G9O-34-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosomal RNA small subunit methyltransferase BUniRule annotation (EC:2.1.1.176UniRule annotation)
Alternative name(s):
16S rRNA m5C967 methyltransferaseUniRule annotation
rRNA (cytosine-C(5)-)-methyltransferase RsmBUniRule annotation
Gene namesi
Name:rsmBUniRule annotation
Synonyms:sunUniRule annotation
Ordered Locus Names:ESA_00037
OrganismiCronobacter sakazakii (strain ATCC BAA-894) (Enterobacter sakazakii)
Taxonomic identifieri290339 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeCronobacter
Proteomesi
  • UP000000260 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003661471 – 429Ribosomal RNA small subunit methyltransferase BAdd BLAST429

Proteomic databases

PRIDEiA7MPE7

Interactioni

Protein-protein interaction databases

STRINGi290339.ESA_00037

Structurei

3D structure databases

ProteinModelPortaliA7MPE7
SMRiA7MPE7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni254 – 260S-adenosyl-L-methionine bindingUniRule annotation7

Sequence similaritiesi

Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CYJ Bacteria
COG0144 LUCA
HOGENOMiHOG000037300
KOiK03500
OMAiLRVNRQH

Family and domain databases

Gene3Di1.10.940.10, 1 hit
HAMAPiMF_01856 16SrRNA_methyltr_B, 1 hit
InterProiView protein in InterPro
IPR018314 Fmu/NOL1/Nop2p_CS
IPR001678 MeTrfase_RsmB/NOP2
IPR035926 NusB-like_sf
IPR006027 NusB_RsmB_TIM44
IPR023267 RCMT
IPR004573 rRNA_ssu_MeTfrase_B
IPR023541 rRNA_ssu_MeTfrase_B_ent
IPR029063 SAM-dependent_MTases
PfamiView protein in Pfam
PF01189 Methyltr_RsmB-F, 1 hit
PF01029 NusB, 1 hit
PRINTSiPR02008 RCMTFAMILY
SUPFAMiSSF48013 SSF48013, 1 hit
SSF53335 SSF53335, 1 hit
TIGRFAMsiTIGR00563 rsmB, 1 hit
PROSITEiView protein in PROSITE
PS01153 NOL1_NOP2_SUN, 1 hit
PS51686 SAM_MT_RSMB_NOP, 1 hit

Sequencei

Sequence statusi: Complete.

A7MPE7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKSINLRSL AAQAIEQVVE KGQSLSTVLP PLQHKVSDKD KALLQELCFG
60 70 80 90 100
VLRTLSQLEW LINKLMSRPM TGKQRTIHYL IMVGLYQLLY TRIPPHAALA
110 120 130 140 150
ETVEGAVAIK RMQFKGLING VLRQFQRQQD ELLAEFSGQD ARWLHPMWLL
160 170 180 190 200
NRFQTAWPRE WQAVVEANNE RPPMWLRVNR QHHSRDEWLK LLEENGMTGH
210 220 230 240 250
IHPRYPDAVR LDAPAPVSAL PGFEQGWVTV QDASAQGCVE LLAPQNGETI
260 270 280 290 300
LDLCAAPGGK TTHILEAAPQ ASVMAVDVDA QRISRVYENL KRLKMKADVK
310 320 330 340 350
VGDGRFPSTW CGETQFDRIL LDAPCSATGV IRRHPDIKWL RRDSDINELA
360 370 380 390 400
QLQSEILDAI WPHLKPGGTL LYATCSVLPE ENSEQIRAFL SRTPDAQLDG
410 420
TGSTQTPGIQ NLPGATEGDG FFYAKLIKK
Length:429
Mass (Da):48,163
Last modified:October 2, 2007 - v1
Checksum:i5648B0E76C793E48
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000783 Genomic DNA Translation: ABU75346.1
RefSeqiWP_012123587.1, NC_009778.1

Genome annotation databases

EnsemblBacteriaiABU75346; ABU75346; ESA_00037
KEGGiesa:ESA_00037
PATRICifig|290339.8.peg.35

Similar proteinsi

Entry informationi

Entry nameiRSMB_CROS8
AccessioniPrimary (citable) accession number: A7MPE7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: October 2, 2007
Last modified: June 20, 2018
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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