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Entry version 95 (13 Feb 2019)
Sequence version 1 (02 Oct 2007)
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Protein

TANK-binding kinase 1-binding protein 1

Gene

TBKBP1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Adapter protein which constitutively binds TBK1 and IKBKE playing a role in antiviral innate immunity.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processHost-virus interaction, Immunity, Innate immunity

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
TANK-binding kinase 1-binding protein 1
Short name:
TBK1-binding protein 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TBKBP1Imported
Synonyms:KIAA0775Imported, SINTBAD
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 17

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000198933.9

Human Gene Nomenclature Database

More...
HGNCi
HGNC:30140 TBKBP1

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
608476 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_A7MCY6

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
9755

Open Targets

More...
OpenTargetsi
ENSG00000198933

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA142670830

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
TBKBP1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003246541 – 615TANK-binding kinase 1-binding protein 1Add BLAST615

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei184PhosphoserineCombined sources1
Modified residuei365PhosphoserineCombined sources1
Modified residuei372PhosphoserineCombined sources1
Modified residuei379PhosphoserineCombined sources1
Modified residuei385PhosphoserineCombined sources1
Modified residuei400PhosphoserineCombined sources1
Modified residuei415PhosphoserineCombined sources1
Modified residuei504PhosphoserineCombined sources1
Modified residuei534PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
A7MCY6

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
A7MCY6

MaxQB - The MaxQuant DataBase

More...
MaxQBi
A7MCY6

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
A7MCY6

PRoteomics IDEntifications database

More...
PRIDEi
A7MCY6

ProteomicsDB human proteome resource

More...
ProteomicsDBi
1810
1811 [A7MCY6-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
A7MCY6

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
A7MCY6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Detected in leukocytes, lung, placenta, small intestine, liver, kidney, spleen, muscle, heart, brain and at low levels in thymus.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000198933 Expressed in 176 organ(s), highest expression level in blood

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
A7MCY6 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
A7MCY6 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA062347
HPA064856

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimer. May form a heterodimer with NAP1. Interacts with TKB1 and IKBKE.2 Publications
(Microbial infection) Interacts with vaccinia virus protein C6 (PubMed:21931555).1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
115103, 22 interactors

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
A7MCY6

Database of interacting proteins

More...
DIPi
DIP-27604N

Protein interaction database and analysis system

More...
IntActi
A7MCY6, 15 interactors

Molecular INTeraction database

More...
MINTi
A7MCY6

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000354777

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
A7MCY6

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
A7MCY6

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 279HomodimerizationBy similarityAdd BLAST279
Regioni280 – 329Interaction with TBK1 and IKBKEBy similarityAdd BLAST50

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili48 – 162Sequence analysisAdd BLAST115
Coiled coili221 – 276Sequence analysisAdd BLAST56

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi343 – 434Pro-richSequence analysisAdd BLAST92

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IGJJ Eukaryota
ENOG410ZK7E LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000153704

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000154514

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG108550

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
A7MCY6

KEGG Orthology (KO)

More...
KOi
K12652

Identification of Orthologs from Complete Genome Data

More...
OMAi
LSHAGWP

Database of Orthologous Groups

More...
OrthoDBi
621943at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
A7MCY6

TreeFam database of animal gene trees

More...
TreeFami
TF331289

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR024581 TBD

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12845 TBD, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 12 Publications (identifier: A7MCY6-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MESMFEDDIS ILTQEALGPS EVWLDSPGDP SLGGDMCSAS HFALITAYGD
60 70 80 90 100
IKERLGGLER ENATLRRRLK VYEIKYPLIS DFGEEHGFSL YEIKDGSLLE
110 120 130 140 150
VEKVSLQQRL NQFQHELQKN KEQEEQLGEM IQAYEKLCVE KSDLETELRE
160 170 180 190 200
MRALVETHLR QICGLEQQLR QQQGLQDAAF SNLSPPPAPA PPCTDLDLHY
210 220 230 240 250
LALRGGSGLS HAGWPGSTPS VSDLERRRLE EALEAAQGEA RGAQLREEQL
260 270 280 290 300
QAECERLQGE LKQLQETRAQ DLASNQSERD MAWVKRVGDD QVNLALAYTE
310 320 330 340 350
LTEELGRLRE LSSLQGRILR TLLQEQARSG GQRHSPLSQR HSPAPQCPSP
360 370 380 390 400
SPPARAAPPC PPCQSPVPQR RSPVPPCPSP QQRRSPASPS CPSPVPQRRS
410 420 430 440 450
PVPPSCQSPS PQRRSPVPPS CPAPQPRPPP PPPPGERTLA ERAYAKPPSH
460 470 480 490 500
HVKAGFQGRR SYSELAEGAA YAGASPPWLQ AEAATLPKPR AYGSELYGPG
510 520 530 540 550
RPLSPRRAFE GIRLRFEKQP SEEDEWAVPT SPPSPEVGTI RCASFCAGFP
560 570 580 590 600
IPESPAATAY AHAEHAQSWP SINLLMETVG SDIRSCPLCQ LGFPVGYPDD
610
ALIKHIDSHL ENSKI
Length:615
Mass (Da):67,702
Last modified:October 2, 2007 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC8F42919164A554E
GO
Isoform 21 Publication (identifier: A7MCY6-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     186-222: PPAPAPPCTDLDLHYLALRGGSGLSHAGWPGSTPSVS → RRARAVLAVHQLADGDGGLRHPQLPPLPAGFPCRVPG
     223-615: Missing.

Note: No experimental confirmation available.Curated
Show »
Length:222
Mass (Da):25,043
Checksum:iE52578DA01C2B322
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F5H1U4F5H1U4_HUMAN
TANK-binding kinase 1-binding prote...
TBKBP1
208Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3KS71J3KS71_HUMAN
TANK-binding kinase 1-binding prote...
TBKBP1
195Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAA34495 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_052714186 – 222PPAPA…TPSVS → RRARAVLAVHQLADGDGGLR HPQLPPLPAGFPCRVPG in isoform 2. 1 PublicationAdd BLAST37
Alternative sequenceiVSP_052715223 – 615Missing in isoform 2. 1 PublicationAdd BLAST393

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB018318 mRNA Translation: BAA34495.2 Different initiation.
BC111418 mRNA Translation: AAI11419.1
BC152407 mRNA Translation: AAI52408.1
BC167150 mRNA Translation: AAI67150.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS45722.1 [A7MCY6-1]

NCBI Reference Sequences

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RefSeqi
NP_055541.1, NM_014726.2 [A7MCY6-1]
XP_005257916.1, XM_005257859.4 [A7MCY6-1]
XP_005257917.1, XM_005257860.4 [A7MCY6-1]
XP_005257918.1, XM_005257861.4 [A7MCY6-1]
XP_005257919.1, XM_005257862.3 [A7MCY6-1]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.94790

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000361722; ENSP00000354777; ENSG00000198933 [A7MCY6-1]
ENST00000622396; ENSP00000484395; ENSG00000198933 [A7MCY6-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
9755

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:9755

UCSC genome browser

More...
UCSCi
uc002ilu.4 human [A7MCY6-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB018318 mRNA Translation: BAA34495.2 Different initiation.
BC111418 mRNA Translation: AAI11419.1
BC152407 mRNA Translation: AAI52408.1
BC167150 mRNA Translation: AAI67150.1
CCDSiCCDS45722.1 [A7MCY6-1]
RefSeqiNP_055541.1, NM_014726.2 [A7MCY6-1]
XP_005257916.1, XM_005257859.4 [A7MCY6-1]
XP_005257917.1, XM_005257860.4 [A7MCY6-1]
XP_005257918.1, XM_005257861.4 [A7MCY6-1]
XP_005257919.1, XM_005257862.3 [A7MCY6-1]
UniGeneiHs.94790

3D structure databases

ProteinModelPortaliA7MCY6
SMRiA7MCY6
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi115103, 22 interactors
CORUMiA7MCY6
DIPiDIP-27604N
IntActiA7MCY6, 15 interactors
MINTiA7MCY6
STRINGi9606.ENSP00000354777

PTM databases

iPTMnetiA7MCY6
PhosphoSitePlusiA7MCY6

Polymorphism and mutation databases

BioMutaiTBKBP1

Proteomic databases

EPDiA7MCY6
jPOSTiA7MCY6
MaxQBiA7MCY6
PaxDbiA7MCY6
PRIDEiA7MCY6
ProteomicsDBi1810
1811 [A7MCY6-2]

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000361722; ENSP00000354777; ENSG00000198933 [A7MCY6-1]
ENST00000622396; ENSP00000484395; ENSG00000198933 [A7MCY6-2]
GeneIDi9755
KEGGihsa:9755
UCSCiuc002ilu.4 human [A7MCY6-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
9755
DisGeNETi9755
EuPathDBiHostDB:ENSG00000198933.9

GeneCards: human genes, protein and diseases

More...
GeneCardsi
TBKBP1
HGNCiHGNC:30140 TBKBP1
HPAiHPA062347
HPA064856
MIMi608476 gene
neXtProtiNX_A7MCY6
OpenTargetsiENSG00000198933
PharmGKBiPA142670830

Human Unidentified Gene-Encoded large proteins database

More...
HUGEi
Search...

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IGJJ Eukaryota
ENOG410ZK7E LUCA
GeneTreeiENSGT00940000153704
HOGENOMiHOG000154514
HOVERGENiHBG108550
InParanoidiA7MCY6
KOiK12652
OMAiLSHAGWP
OrthoDBi621943at2759
PhylomeDBiA7MCY6
TreeFamiTF331289

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
9755

Protein Ontology

More...
PROi
PR:A7MCY6

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000198933 Expressed in 176 organ(s), highest expression level in blood
ExpressionAtlasiA7MCY6 baseline and differential
GenevisibleiA7MCY6 HS

Family and domain databases

InterProiView protein in InterPro
IPR024581 TBD
PfamiView protein in Pfam
PF12845 TBD, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTBKB1_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A7MCY6
Secondary accession number(s): B2RZG6, O94873, Q14DW3
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: October 2, 2007
Last modified: February 13, 2019
This is version 95 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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