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Protein
Submitted name:

Pigment epithelium-derived factor

Gene

PEDF

Organism
Cavia porcellus (Guinea pig)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Protein family/group databases

MEROPSiI04.979

Names & Taxonomyi

Protein namesi
Submitted name:
Pigment epithelium-derived factorImported
Gene namesi
Name:PEDFImported
OrganismiCavia porcellus (Guinea pig)Imported
Taxonomic identifieri10141 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaHystricomorphaCaviidaeCavia

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
ChainiPRO_500271228820 – 418Sequence analysisAdd BLAST399

Proteomic databases

PRIDEiA7L6D3

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini62 – 415SERPINInterPro annotationAdd BLAST354

Sequence similaritiesi

Belongs to the serpin family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG2392 Eukaryota
COG4826 LUCA
HOGENOMiHOG000115489
HOVERGENiHBG106911

Family and domain databases

CDDicd02052 PEDF, 1 hit
InterProiView protein in InterPro
IPR033832 PEDF
IPR023795 Serpin_CS
IPR023796 Serpin_dom
IPR000215 Serpin_fam
IPR036186 Serpin_sf
PANTHERiPTHR11461 PTHR11461, 1 hit
PfamiView protein in Pfam
PF00079 Serpin, 1 hit
SMARTiView protein in SMART
SM00093 SERPIN, 1 hit
SUPFAMiSSF56574 SSF56574, 1 hit
PROSITEiView protein in PROSITE
PS00284 SERPIN, 1 hit

Sequencei

Sequence statusi: Complete.

A7L6D3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQVLVLLLWT GALLGRGSCQ DIASNPEDSP SPESTGEPVE EEDPFFKVPV
60 70 80 90 100
NKLAAAISNF GYDLYRVRSI ESPTTNVLLS PLSVATALSA LSLGAEQRTE
110 120 130 140 150
ATIHRALYYD MISNPDIHST YKELLATVTA PQKNLKSASR IVFERKLRIK
160 170 180 190 200
SSLVALLEKS YSTRPRILTG NPRIDLQEIS NWVQAQMKGK ITRSTREVPS
210 220 230 240 250
GISILLLGVA YFKGQWVTKF DSRKTSLQDF HLDEERTVKV PMMSDPKAII
260 270 280 290 300
RYGLDTDLNC KIAQLPLTGS MSIIFFLPMR ATQNLTMIEE SLTSEFVHDI
310 320 330 340 350
NRELKAVQAV LSIPRLKLSF EGELTKSLQE MKLHSLFESP DFSKITGKPI
360 370 380 390 400
KLTQVEHRAG FEWNEEGAPG TSTNSDLQPT GFTFSLDYHL NQPFIFVLRD
410
TDTGALLFIG KILDPRST
Length:418
Mass (Da):46,684
Last modified:July 1, 2008 - v3
Checksum:iE0F22DD39A1CBAE7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF679792 mRNA Translation: ABS12244.3
RefSeqiNP_001166531.1, NM_001173060.1

Genome annotation databases

GeneIDi100216362

Similar proteinsi

Entry informationi

Entry nameiA7L6D3_CAVPO
AccessioniPrimary (citable) accession number: A7L6D3
Entry historyiIntegrated into UniProtKB/TrEMBL: September 11, 2007
Last sequence update: July 1, 2008
Last modified: October 25, 2017
This is version 53 of the entry and version 3 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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