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Entry version 72 (11 Dec 2019)
Sequence version 1 (11 Sep 2007)
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Protein
Submitted name:

Beta-galactosidase/beta-glucuronidase

Gene

VEx25_A0220

Organism
Vibrio antiquarius (strain Ex25)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

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BioCyci
VSP150340:G1GGJ-3812-MONOMER

Protein family/group databases

Carbohydrate-Active enZymes

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CAZyi
GH2 Glycoside Hydrolase Family 2

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Beta-galactosidase/beta-glucuronidaseImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:VEx25_A0220Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiVibrio antiquarius (strain Ex25)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri150340 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrioVibrio diabolicus subgroup

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini641 – 727Mannosidase_igInterPro annotationAdd BLAST87
Domaini733 – 802Ig_mannosidaseInterPro annotationAdd BLAST70

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

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HOGENOMi
HOG000186861

Identification of Orthologs from Complete Genome Data

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OMAi
MFRRYDF

Database of Orthologous Groups

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OrthoDBi
245411at2

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

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Gene3Di
2.60.120.260, 1 hit
2.60.40.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR036156 Beta-gal/glucu_dom_sf
IPR041625 Beta-mannosidase_Ig
IPR008979 Galactose-bd-like_sf
IPR017853 Glycoside_hydrolase_SF
IPR013783 Ig-like_fold
IPR041447 Mannosidase_ig

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF17753 Ig_mannosidase, 1 hit
PF17786 Mannosidase_ig, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49303 SSF49303, 2 hits
SSF49785 SSF49785, 1 hit
SSF51445 SSF51445, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A7JZJ2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAHFELNGQW LLTSPQRPDI EIPMFIPGDN VSALLQAEQI PDPYFADNEN
60 70 80 90 100
KVRWIEECEW HISREFDVDA FTLSAKQIWM TLTRVDTLAT FYINGELALT
110 120 130 140 150
CRNMFTQQRV DIKPHLKQGT NTIRVEFARV DLEGIARAKK LPFPIPSAMG
160 170 180 190 200
NNQIPHMNLI RKTQCHSGWD WGICLMVSGI YDPIQIDIVN ELWLKGFSTE
210 220 230 240 250
QQWQADGSVF LDVVVEVETD SQRHEMMVEF NGERQCIQTN GSGHYHCQFH
260 270 280 290 300
ISEPQRWWPS GYGEAYLYPI TISCREQKLT RNVGLRQLTL NNQADEHGSA
310 320 330 340 350
MEFIVNGVPI NAKGANWIPV DAMPGRECET RYRNLLQSAV DANMNMIRVW
360 370 380 390 400
GGGQYESEIF YNLCDELGLL VWQDMMFACS LYPSDNDFLK EVEGELRYQI
410 420 430 440 450
SRLKEHPSIA LWCGDNEVIG AIGWYEESKH NKVKYTVNYD RLNRMIEQVI
460 470 480 490 500
TEHDSARRFW PSSPCNGELD FGDAWHDDSK GDMHFWDVWH SGKSFNAYLD
510 520 530 540 550
VNPRFCSEFG FQSWPSFAEV KQFVPEQDWN ITSLTFEQHQ KNPRGNSIIT
560 570 580 590 600
EMFTRYFRFP SGFENMLYLS QVQQAIAIKT ACDHWRAISP VCRGMLYWQL
610 620 630 640 650
NDNWPVSSWS SLEYSGRWKQ LHYHAKRFFA PQYLVFSEHT GKLSLHLLND
660 670 680 690 700
AKEPASVNAL LKWVDWQGEE KQCWSLEQTV IADSNTILWQ LNESVEKDEL
710 720 730 740 750
TSGFLYVEAQ IGEDRISNTW FCTHELKTLP MAKANIDVSI DGSQITLIAD
760 770 780 790 800
KPAFFVHLES DVDGRFSDSS FTLLTNVPMT VEYLGDDVLG MQQSLRVYHL

ND
Length:802
Mass (Da):92,796
Last modified:September 11, 2007 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i64D4502515750B96
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
DS267810 Genomic DNA Translation: EDN58390.1

NCBI Reference Sequences

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RefSeqi
WP_006741373.1, NZ_DS267810.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
ACY53344; ACY53344; VEA_000658
EDN58390; EDN58390; VEx25_A0220

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS267810 Genomic DNA Translation: EDN58390.1
RefSeqiWP_006741373.1, NZ_DS267810.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein family/group databases

CAZyiGH2 Glycoside Hydrolase Family 2

Genome annotation databases

EnsemblBacteriaiACY53344; ACY53344; VEA_000658
EDN58390; EDN58390; VEx25_A0220

Phylogenomic databases

HOGENOMiHOG000186861
OMAiMFRRYDF
OrthoDBi245411at2

Enzyme and pathway databases

BioCyciVSP150340:G1GGJ-3812-MONOMER

Family and domain databases

Gene3Di2.60.120.260, 1 hit
2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR036156 Beta-gal/glucu_dom_sf
IPR041625 Beta-mannosidase_Ig
IPR008979 Galactose-bd-like_sf
IPR017853 Glycoside_hydrolase_SF
IPR013783 Ig-like_fold
IPR041447 Mannosidase_ig
PfamiView protein in Pfam
PF17753 Ig_mannosidase, 1 hit
PF17786 Mannosidase_ig, 1 hit
SUPFAMiSSF49303 SSF49303, 2 hits
SSF49785 SSF49785, 1 hit
SSF51445 SSF51445, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA7JZJ2_VIBAE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A7JZJ2
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: September 11, 2007
Last sequence update: September 11, 2007
Last modified: December 11, 2019
This is version 72 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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