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Protein

Ribonucleoside-diphosphate reductase

Gene

B832R

Organism
Paramecium bursaria Chlorella virus NY2A (PBCV-NY2A)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.UniRule annotation

Catalytic activityi

2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin.UniRule annotation

Pathwayi: DNA replication

This protein is involved in the pathway DNA replication, which is part of Genetic information processing.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway DNA replication and in Genetic information processing.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
Biological processDNA replicationUniRule annotation
LigandATP-bindingPROSITE-ProRule annotation, Nucleotide-binding

Enzyme and pathway databases

UniPathwayi
UPA00326

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonucleoside-diphosphate reductaseUniRule annotation (EC:1.17.4.1UniRule annotation)
Gene namesi
Name:B832RImported
ORF Names:NY2A_B832RImported
OrganismiParamecium bursaria Chlorella virus NY2A (PBCV-NY2A)Imported
Taxonomic identifieri46021 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stagePhycodnaviridaeChlorovirus
Virus hostiChlorella [TaxID: 114055]
Proteomesi
  • UP000202419 Componenti: Genome

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 113ATP-coneInterPro annotationAdd BLAST104
Domaini626 – 669DOD-type homing endonucleaseInterPro annotationAdd BLAST44

Sequence similaritiesi

Belongs to the ribonucleoside diphosphate reductase large chain family.UniRule annotation

Family and domain databases

Gene3Di3.10.28.10, 1 hit
InterProiView protein in InterPro
IPR005144 ATP-cone_dom
IPR003587 Hint_dom_N
IPR036844 Hint_dom_sf
IPR027434 Homing_endonucl
IPR006142 INTEIN
IPR004042 Intein_endonuc
IPR006141 Intein_N
IPR004860 LAGLIDADG_2
IPR013346 NrdE_NrdA
IPR000788 RNR_lg_C
IPR013509 RNR_lsu_N
IPR008926 RNR_R1-su_N
IPR039718 Rrm1
PANTHERiPTHR11573 PTHR11573, 2 hits
PfamiView protein in Pfam
PF03477 ATP-cone, 1 hit
PF14528 LAGLIDADG_3, 1 hit
PF02867 Ribonuc_red_lgC, 1 hit
PF00317 Ribonuc_red_lgN, 1 hit
PRINTSiPR00379 INTEIN
SMARTiView protein in SMART
SM00306 HintN, 1 hit
SUPFAMiSSF48168 SSF48168, 1 hit
SSF51294 SSF51294, 1 hit
SSF55608 SSF55608, 1 hit
TIGRFAMsiTIGR01445 intein_Nterm, 1 hit
TIGR02506 NrdE_NrdA, 1 hit
PROSITEiView protein in PROSITE
PS51161 ATP_CONE, 1 hit
PS50819 INTEIN_ENDONUCLEASE, 1 hit
PS50817 INTEIN_N_TER, 1 hit
PS00089 RIBORED_LARGE, 1 hit

Sequencei

Sequence statusi: Complete.

A7IY07-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVGRPMNRLM VVLKRDGSKE NISFDKILQR IQRLCWPINS KPVYKGSRAM
60 70 80 90 100
TGLSVDVSKI VASVCASIVD GISTVQLDEL TADKSASMTT EHPDYGILAA
110 120 130 140 150
RISVSNLQKQ THDKITDAYA EIAHLLSNDF KENIEKHADE YQSFIDYDRD
160 170 180 190 200
YDFDYFGFKT MERLYLTKVN NKIVERPQHV YLRVAIGLWG SDIARVKETY
210 220 230 240 250
DALSCRKFTH ASPTLFNAGF KKAQLASCFL VTVEDSLGDI YKVLGDCAQL
260 270 280 290 300
SKHGGGLGIN ISEIRGRGSR INGTNGESDG IVPMLKVFDT TSAYANQGGR
310 320 330 340 350
RKGSFAIYLE PHHSDVMDFL LMKRNQGEES LRARNLFYAV WLNDLFMKRV
360 370 380 390 400
ETDAQWSLFD PSECPGLTDA FGDEYAELYE RYEAEGKAKN VVKARDVWNT
410 420 430 440 450
MVTTIIETGQ PYVSNKDAVN KKNMQMNAGT IRGSNLCVAG DTKILTSSGY
460 470 480 490 500
HPIKDMEGKQ VRVWNGYEFS ETIVHKTGVN QKLIMVSLDD GTELRCTPYH
510 520 530 540 550
KFYIETGSRP ADKSRVMEVR AGDLEKGDRI IRFELPTITV GETTMSDKEA
560 570 580 590 600
YTKGFFSADG CVIKSKYGED EYRISVKRED KIEALTKYVD VIKSHTNRFR
610 620 630 640 650
THFYVPDYVQ NKFEVPINSM VNEKISWLAG FMDGDGCVIR YKDIENMQAV
660 670 680 690 700
SINKSFLQDI RLMLQTIGIH STINKFMPNR VMKMPDGRGG TDMYNGAESW
710 720 730 740 750
RLQIDSEGVR KLFALGFTPR RLKMNGSRKR HHKTNKFTRV VSVTDHGDVE
760 770 780 790 800
DTYCFNEPKR HMGVFNGVIT GQCNEIVEYT SKEETAVCVI GSVVLKNYVK
810 820 830 840 850
NDKFDFDDLR KNVKILAKNL DRSIDVMAYP IKEAETSNKL RRPIGVGVQG
860 870 880 890 900
LQDVFFKLRF SYDSPEARDL NREIFEHIYY AAVEASVELA EIHGPYPTFE
910 920 930 940 950
GSPASKGILQ YHLWDVTPKS NLDWRGLEER VKKGIRNSLV TALMPTASTA
960 970 980 990 1000
QICGSVEAFE PITSNLYSRR TLAGEFPVIN SYLVRELIER GTWNEQMKNQ
1010 1020 1030 1040 1050
IIANGGSIQK VIGIHPSVKA VYKTAWDLSM KSVIDMASDR GAFVDQTQSM
1060 1070 1080 1090 1100
NLFLAQPTLK NVTSMLFYGW KSGLKTLQYY LRSKPASSAI AVTIDNDCLV

CSA
Length:1,103
Mass (Da):124,555
Last modified:September 11, 2007 - v1
Checksum:i3DE8471A1F22FA82
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ491002 Genomic DNA Translation: ABT15231.1
RefSeqiYP_001498028.1, NC_009898.1

Genome annotation databases

GeneIDi5659402
KEGGivg:5659402

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ491002 Genomic DNA Translation: ABT15231.1
RefSeqiYP_001498028.1, NC_009898.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi5659402
KEGGivg:5659402

Enzyme and pathway databases

UniPathwayi
UPA00326

Family and domain databases

Gene3Di3.10.28.10, 1 hit
InterProiView protein in InterPro
IPR005144 ATP-cone_dom
IPR003587 Hint_dom_N
IPR036844 Hint_dom_sf
IPR027434 Homing_endonucl
IPR006142 INTEIN
IPR004042 Intein_endonuc
IPR006141 Intein_N
IPR004860 LAGLIDADG_2
IPR013346 NrdE_NrdA
IPR000788 RNR_lg_C
IPR013509 RNR_lsu_N
IPR008926 RNR_R1-su_N
IPR039718 Rrm1
PANTHERiPTHR11573 PTHR11573, 2 hits
PfamiView protein in Pfam
PF03477 ATP-cone, 1 hit
PF14528 LAGLIDADG_3, 1 hit
PF02867 Ribonuc_red_lgC, 1 hit
PF00317 Ribonuc_red_lgN, 1 hit
PRINTSiPR00379 INTEIN
SMARTiView protein in SMART
SM00306 HintN, 1 hit
SUPFAMiSSF48168 SSF48168, 1 hit
SSF51294 SSF51294, 1 hit
SSF55608 SSF55608, 1 hit
TIGRFAMsiTIGR01445 intein_Nterm, 1 hit
TIGR02506 NrdE_NrdA, 1 hit
PROSITEiView protein in PROSITE
PS51161 ATP_CONE, 1 hit
PS50819 INTEIN_ENDONUCLEASE, 1 hit
PS50817 INTEIN_N_TER, 1 hit
PS00089 RIBORED_LARGE, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA7IY07_PBCVN
AccessioniPrimary (citable) accession number: A7IY07
Entry historyiIntegrated into UniProtKB/TrEMBL: September 11, 2007
Last sequence update: September 11, 2007
Last modified: November 7, 2018
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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