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Protein

tRNA pseudouridine synthase D

Gene

truD

Organism
Anaeromyxobacter sp. (strain Fw109-5)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(13) = tRNA pseudouridine(13).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei78NucleophileUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processtRNA processing

Enzyme and pathway databases

BioCyciASP404589:G1G9J-3896-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase DUniRule annotation (EC:5.4.99.27UniRule annotation)
Alternative name(s):
tRNA pseudouridine(13) synthaseUniRule annotation
tRNA pseudouridylate synthase DUniRule annotation
tRNA-uridine isomerase DUniRule annotation
Gene namesi
Name:truDUniRule annotation
Ordered Locus Names:Anae109_3769
OrganismiAnaeromyxobacter sp. (strain Fw109-5)
Taxonomic identifieri404589 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaMyxococcalesCystobacterineaeAnaeromyxobacteraceaeAnaeromyxobacter
Proteomesi
  • UP000006382 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001498401 – 349tRNA pseudouridine synthase DAdd BLAST349

Interactioni

Protein-protein interaction databases

STRINGi404589.Anae109_3769

Structurei

3D structure databases

ProteinModelPortaliA7HGV2
SMRiA7HGV2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini150 – 304TRUDUniRule annotationAdd BLAST155

Sequence similaritiesi

Belongs to the pseudouridine synthase TruD family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4106NZV Bacteria
COG0585 LUCA
HOGENOMiHOG000224848
KOiK06176
OMAiLWLWVEK
OrthoDBiPOG091H03KK

Family and domain databases

HAMAPiMF_01082 TruD, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR001656 PsdUridine_synth_TruD
IPR020119 PsdUridine_synth_TruD_CS
IPR011760 PsdUridine_synth_TruD_insert
PANTHERiPTHR13326 PTHR13326, 2 hits
PfamiView protein in Pfam
PF01142 TruD, 2 hits
SUPFAMiSSF55120 SSF55120, 1 hit
PROSITEiView protein in PROSITE
PS50984 TRUD, 1 hit
PS01268 UPF0024, 1 hit

Sequencei

Sequence statusi: Complete.

A7HGV2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTDAPLVTAE LPGSGGSLRR SPEDFRVDEV PAYLPSGAGP HLYLRVEKRG
60 70 80 90 100
RTTRDALRTL ARALGVPERD AGYAGLKDKD AVTTQWLSFP AARDPEPQAL
110 120 130 140 150
ASEGLRVLEV SRHANKLRPG HVRANRFQLA VRGGDLARAQ AAAAALAERG
160 170 180 190 200
LPNLFGPQRF GTEGRNAEVG RALLLGDPSP EARRAARDRF LRRLSISAYQ
210 220 230 240 250
ALLFNRWLAE RMADGLFATA VAGDVLKKLD TGGLFTCADP AVDGPRVQRF
260 270 280 290 300
EVSPAGPMFG HKLRAAEGEA LAREERLLAA EGIQLSDFAR GGGEAEGTRR
310 320 330 340
AARLRVEVAL APLEDGYLAT FELPKGSYAT VVMRELMKAG AELPEADED
Length:349
Mass (Da):37,581
Last modified:September 11, 2007 - v1
Checksum:iA058BA583C5DDF55
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000769 Genomic DNA Translation: ABS27948.1
RefSeqiWP_012098576.1, NC_009675.1

Genome annotation databases

EnsemblBacteriaiABS27948; ABS27948; Anae109_3769
KEGGiafw:Anae109_3769

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000769 Genomic DNA Translation: ABS27948.1
RefSeqiWP_012098576.1, NC_009675.1

3D structure databases

ProteinModelPortaliA7HGV2
SMRiA7HGV2
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi404589.Anae109_3769

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABS27948; ABS27948; Anae109_3769
KEGGiafw:Anae109_3769

Phylogenomic databases

eggNOGiENOG4106NZV Bacteria
COG0585 LUCA
HOGENOMiHOG000224848
KOiK06176
OMAiLWLWVEK
OrthoDBiPOG091H03KK

Enzyme and pathway databases

BioCyciASP404589:G1G9J-3896-MONOMER

Family and domain databases

HAMAPiMF_01082 TruD, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR001656 PsdUridine_synth_TruD
IPR020119 PsdUridine_synth_TruD_CS
IPR011760 PsdUridine_synth_TruD_insert
PANTHERiPTHR13326 PTHR13326, 2 hits
PfamiView protein in Pfam
PF01142 TruD, 2 hits
SUPFAMiSSF55120 SSF55120, 1 hit
PROSITEiView protein in PROSITE
PS50984 TRUD, 1 hit
PS01268 UPF0024, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiTRUD_ANADF
AccessioniPrimary (citable) accession number: A7HGV2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: September 11, 2007
Last modified: November 7, 2018
This is version 61 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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