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Entry version 53 (16 Jan 2019)
Sequence version 1 (11 Sep 2007)
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Protein

Protein RUBCNL-like

Gene

RUBCNL

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May act as a tumor suppressor.By similarity

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein RUBCNL-likeCurated
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:RUBCNLBy similarity
Synonyms:KIAA0226L
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiBos taurus (Bovine)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9913 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000009136 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 12

Organism-specific databases

Vertebrate Gene Nomenclature Database

More...
VGNCi
VGNC:34213 RUBCNL

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003505661 – 663Protein RUBCNL-likeAdd BLAST663

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

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PaxDbi
A7E316

PRoteomics IDEntifications database

More...
PRIDEi
A7E316

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

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Bgeei
ENSBTAG00000013371 Expressed in 9 organ(s), highest expression level in spleen

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
ENOG410ITGP Eukaryota
ENOG410YE6N LUCA

Ensembl GeneTree

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GeneTreei
ENSGT00940000160585

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

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HOGENOMi
HOG000082444

The HOVERGEN Database of Homologous Vertebrate Genes

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HOVERGENi
HBG081255

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
A7E316

Identification of Orthologs from Complete Genome Data

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OMAi
VASCELC

Database of Orthologous Groups

More...
OrthoDBi
177737at2759

TreeFam database of animal gene trees

More...
TreeFami
TF317067

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR025258 Zf-RING_9

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13901 zf-RING_9, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01175 DUF4206, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A7E316-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVSQSSGRQD SPVDPWEGVS DDPGNTDGLP SLLDTEHPFC PSDIRFTRHR
60 70 80 90 100
AAWINPPCAQ QQLQDASPQV LAVGNRESHT ASNTKSPLGT SPLSLGDSVV
110 120 130 140 150
ETSLPKGTTD SLGSSSAWGT AGNGSDSSVT LKEERAGLPR RCPHTSLITS
160 170 180 190 200
SKTVSGPPCP EDGRAFFKPS QLTASADADA VQVGGRTVSS NSFSPEAFVL
210 220 230 240 250
PVDAEKENAH FYVADMIISV MEKMKCNILS QQHTETWSTE EAGRSLGNSR
260 270 280 290 300
ADLEGTFYTH VKQESGSSTS SDSGYEGCVL QVSPVVETPT FSEVTEEDCK
310 320 330 340 350
CDFDDFVIVE LGDFSNTTEP CGCSSDTSKS VIHEPNFNSA ELIAKELYRV
360 370 380 390 400
FRKCWMLAEV HYQLTGSLDA AGSIVINEER VQKDFESSTD VVQEIKLKSR
410 420 430 440 450
IRGTGDWAPP RFQIIFDIHP PLKRDLVVIA QNFFCAGCGT PIEPKFVKRL
460 470 480 490 500
RYCEYLGKYF CDCCHSYSES CIPARILRMW DFRKYYVSNF SKRLLDHIWH
510 520 530 540 550
EPIFNLLHVS HGLYTKAKEL DRVREIQEQL FHIKKLLKTC RFAESTLKEF
560 570 580 590 600
EQLPGHLTEA LHLFSLEDMV KVKKGLLAPL LKDILKASLE HVASCELCQG
610 620 630 640 650
KGFICEFCRS TAVIFPFQTA TCRRCSACRA CFHKQCFQSS KCPRCARITA
660
RRRLLESLPS AAT
Length:663
Mass (Da):73,604
Last modified:September 11, 2007 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i856EBAAC10AE8277
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
BC151662 mRNA Translation: AAI51663.1

NCBI Reference Sequences

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RefSeqi
NP_001095511.1, NM_001102041.2
XP_010809010.1, XM_010810708.2
XP_010809011.1, XM_010810709.2
XP_010809012.1, XM_010810710.2

UniGene gene-oriented nucleotide sequence clusters

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UniGenei
Bt.59031

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSBTAT00000017794; ENSBTAP00000017794; ENSBTAG00000013371

Database of genes from NCBI RefSeq genomes

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GeneIDi
517231

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
bta:517231

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC151662 mRNA Translation: AAI51663.1
RefSeqiNP_001095511.1, NM_001102041.2
XP_010809010.1, XM_010810708.2
XP_010809011.1, XM_010810709.2
XP_010809012.1, XM_010810710.2
UniGeneiBt.59031

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Proteomic databases

PaxDbiA7E316
PRIDEiA7E316

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSBTAT00000017794; ENSBTAP00000017794; ENSBTAG00000013371
GeneIDi517231
KEGGibta:517231

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
80183
VGNCiVGNC:34213 RUBCNL

Phylogenomic databases

eggNOGiENOG410ITGP Eukaryota
ENOG410YE6N LUCA
GeneTreeiENSGT00940000160585
HOGENOMiHOG000082444
HOVERGENiHBG081255
InParanoidiA7E316
OMAiVASCELC
OrthoDBi177737at2759
TreeFamiTF317067

Gene expression databases

BgeeiENSBTAG00000013371 Expressed in 9 organ(s), highest expression level in spleen

Family and domain databases

InterProiView protein in InterPro
IPR025258 Zf-RING_9
PfamiView protein in Pfam
PF13901 zf-RING_9, 1 hit
SMARTiView protein in SMART
SM01175 DUF4206, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRUBCL_BOVIN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A7E316
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 23, 2008
Last sequence update: September 11, 2007
Last modified: January 16, 2019
This is version 53 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Complete proteome, Reference proteome
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