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Entry version 109 (02 Jun 2021)
Sequence version 1 (11 Sep 2007)
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Protein

Mortality factor related protein 1

Gene

mrg-1

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Chromodomain-containing protein involved in the remodeling of chromatin thereby regulating various processes including transcription, chromosome synapsis and genome integrity (PubMed:22172672, PubMed:22212480, PubMed:17215300, PubMed:30929290).

Mainly binds genomic loci carrying trimethylated histone H3 'Lys-36' (H3K36me3) or 'Lys-4' (H3K4me3), and acetylated histone H3 'Lys-9' (H3K9ac), 'Lys-27' (H3K27ac) (PubMed:30425042, PubMed:31118512).

During meiosis, required for the presynaptic pairing of homologous chromosomal regions outside of the pairing center and for the progression of chromosome synapsis (PubMed:22172672, PubMed:22212480).

Essential maternal factor required in postembryonic germline development and in maintaining germ cell identity (PubMed:12175490, PubMed:30425042).

Plays an important role in maintaining genomic integrity in primordial germ cells (PGCs) during meiosis by regulating DNA double-strand break (DSB) repair and synapsis (PubMed:22212480, PubMed:30929290).

Also, required for chromatin-based transcriptional silencing in PGCs and for silencing of X-linked genes in the maternal germ line (PubMed:17215300, PubMed:30929290).

By retaining histone acetyltransferase, cbp-1, in euchromatin, promotes the anchoring of heterochromatin at the inner nuclear membrane in intestinal and hypodermal cells (PubMed:31118512).

7 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionChromatin regulator
Biological processDNA damage, DNA repair, Meiosis, Transcription, Transcription regulation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Mortality factor related protein 11 PublicationImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:mrg-11 PublicationImported
ORF Names:Y37D8A.9Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegansImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome III

Organism-specific databases

WormBase

More...
WormBasei
Y37D8A.9a ; CE20213 ; WBGene00003406 ; mrg-1
Y37D8A.9b ; CE41465 ; WBGene00003406 ; mrg-1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Chromosome, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Maternal-effect lethality and sterility (PubMed:17215300). Primordial germ cells (PGCs) do not proliferate normally and death of germ cells may be as a result of necrosis or increased apoptosis (PubMed:17215300, PubMed:22212480). Increased proportion of oocytes with fragmented chromosomes as a result of irradiation (PubMed:22212480). Tumorous germline phenotype that is suppressed on a rfp-1;glp-1 double mutant background (PubMed:25564623). Germline progression from leptotene/zygotene to pachytene is defective (PubMed:22212480). Perinuclear anchoring of heterochromatin in intestinal or hypodermal cells is disrupted and exacerbated on a cec-4 mutant background, but is partially blocked by RNAi-mediated knockdown of cbp-1 or atf-8 (PubMed:31118512). RNAi-mediated knockdown causes defective homologous chromosome pairing, complete absence of the germline in almost all adult F1 progeny and slight underdevelopment of the somatic gonad (PubMed:12175490, PubMed:22172672). RNAi-mediated knockdown strongly blocks mitosis of PGCs at early larval stages, and the arrested PGCs may degenerate during late larval stages (PubMed:12175490). RNAi-mediated knockdown induces germ cells to undergo conversion into neuron-like cells (PubMed:30425042). RNAi-mediated knockdown causes a slight increase in levels of the constitutive heterochromatin mark, trimethylated histone H3 'Lys-9' (H3K9me3), and an increase of acetylated histone H3 'Lys-14' (H3K14ac) (PubMed:30425042). Simultaneous RNAi-mediated knockdown of mep-1 suppresses the ectopic expression of pgl-1 protein and the overexpression of pgl-1 mRNA in larvae (PubMed:17215300). RNAi-mediated knockdown induces germ cell apoptosis; however, on clk-2 or cep-1 mutant backgrounds apoptosis is reduced substantially (PubMed:22212480).7 Publications

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004515961 – 337Mortality factor related protein 1Add BLAST337

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
A7DTF0

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
A7DTF0

PeptideAtlas

More...
PeptideAtlasi
A7DTF0

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
A7DTF0

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in oocytes (at protein level) (PubMed:12175490). Expressed mainly in germ cells, but also at lower levels in several somatic cell types, including intestinal cells (PubMed:17215300).2 Publications

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expressed in embryos, L1 larvae and adult hermaphrodites and decreases drastically between the L2 and L4 larval stages (at protein level) (PubMed:12175490, PubMed:17215300). In late embryos and young larvae, expressed at higher levels in the two primordial germ cells (PGCs), Z2 and Z3, than in somatic blastomeres (PubMed:17215300, PubMed:30929290). Expressed at a relatively constant level throughout the distal end of the gonad at the L1 stage, with no decrease as cells enter into meiotic prophase (PubMed:25564623).4 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
WBGene00003406, Expressed in multi-cellular organism and 5 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
A7DTF0, baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the SIN3S complex, which contains at least sin-3, hda-1, athp-1 and mrg-1 (PubMed:31602465).

Interacts with cfp-1, a component of the SET2 complex (PubMed:31602465).

Interacts with rfp-1 (PubMed:25564623).

2 Publications

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
A7DTF0, 5 interactors

STRING: functional protein association networks

More...
STRINGi
6239.Y37D8A.9b

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
A7DTF0

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini122 – 327MRGPROSITE-ProRule annotationAdd BLAST206

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni75 – 113DisorderedSequence analysisAdd BLAST39

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi90 – 108Basic and acidic residuesSequence analysisAdd BLAST19

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3001, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000182965

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_039566_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
A7DTF0

Identification of Orthologs from Complete Genome Data

More...
OMAi
DCFYEAK

Database of Orthologous Groups

More...
OrthoDBi
1624495at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
A7DTF0

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.274.30, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR016197, Chromo-like_dom_sf
IPR008676, MRG
IPR038217, MRG_C_sf
IPR026541, MRG_dom
IPR025995, Tudor-knot

The PANTHER Classification System

More...
PANTHERi
PTHR10880, PTHR10880, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF05712, MRG, 1 hit
PF11717, Tudor-knot, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF038133, HAT_Nua4_EAF3/MRG15, 1 hit

Superfamily database of structural and functional annotation

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SUPFAMi
SSF54160, SSF54160, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51640, MRG, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform bImported (identifier: A7DTF0-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSSKKNFEVG ENVACIYKGK PYDAKITDIK TNSDGKELYC VHFKGWNNRY
60 70 80 90 100
DEKIPVGEEK DRIFKGTASE YAEKHNAELP TTALKPKKKS LAAEAPRDDR
110 120 130 140 150
DDTPGTSKGK KAKSVTIAPV MTADDMKVEL PKPLRKILID DYDLVCRYFI
160 170 180 190 200
NIVPHEYSVD QIIEDYIKTI PVSNEQMRTV DDLLIEYEEA DIKITNLALI
210 220 230 240 250
CTARGLVDYF NVTLGSSYQL LYKFERPQYN DLVKKRAMEK GIDITNPTAL
260 270 280 290 300
QDSGFRPSQE YGIVHFLRML AKLPDYLKLT QWNDHVINRI MIGVHDLIVF
310 320 330
LNKNHGKYYR GSSDYQGASN DYYRRSLAAD DGVGANQ
Length:337
Mass (Da):38,461
Last modified:September 11, 2007 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i2D24E60DF73C1E5D
GO
Isoform aImported (identifier: A7DTF0-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     216-217: Missing.

Show »
Length:335
Mass (Da):38,287
Checksum:i9417D56111FF7101
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_060821216 – 217Missing in isoform a. Curated2

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BX284603 Genomic DNA Translation: CAA21528.1
BX284603 Genomic DNA Translation: CAO82072.1

Protein sequence database of the Protein Information Resource

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PIRi
T26627

NCBI Reference Sequences

More...
RefSeqi
NP_001122727.1, NM_001129255.2 [A7DTF0-1]
NP_499675.1, NM_067274.3 [A7DTF0-2]

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
Y37D8A.9a.1; Y37D8A.9a.1; WBGene00003406 [A7DTF0-2]
Y37D8A.9b.1; Y37D8A.9b.1; WBGene00003406 [A7DTF0-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
176702

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
cel:CELE_Y37D8A.9

UCSC genome browser

More...
UCSCi
Y37D8A.9b.1, c. elegans

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284603 Genomic DNA Translation: CAA21528.1
BX284603 Genomic DNA Translation: CAO82072.1
PIRiT26627
RefSeqiNP_001122727.1, NM_001129255.2 [A7DTF0-1]
NP_499675.1, NM_067274.3 [A7DTF0-2]

3D structure databases

SMRiA7DTF0
ModBaseiSearch...

Protein-protein interaction databases

IntActiA7DTF0, 5 interactors
STRINGi6239.Y37D8A.9b

PTM databases

iPTMnetiA7DTF0

Proteomic databases

EPDiA7DTF0
PaxDbiA7DTF0
PeptideAtlasiA7DTF0

Genome annotation databases

EnsemblMetazoaiY37D8A.9a.1; Y37D8A.9a.1; WBGene00003406 [A7DTF0-2]
Y37D8A.9b.1; Y37D8A.9b.1; WBGene00003406 [A7DTF0-1]
GeneIDi176702
KEGGicel:CELE_Y37D8A.9
UCSCiY37D8A.9b.1, c. elegans

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
176702
WormBaseiY37D8A.9a ; CE20213 ; WBGene00003406 ; mrg-1
Y37D8A.9b ; CE41465 ; WBGene00003406 ; mrg-1

Phylogenomic databases

eggNOGiKOG3001, Eukaryota
GeneTreeiENSGT00950000182965
HOGENOMiCLU_039566_0_0_1
InParanoidiA7DTF0
OMAiDCFYEAK
OrthoDBi1624495at2759
PhylomeDBiA7DTF0

Gene expression databases

BgeeiWBGene00003406, Expressed in multi-cellular organism and 5 other tissues
ExpressionAtlasiA7DTF0, baseline and differential

Family and domain databases

Gene3Di1.10.274.30, 1 hit
InterProiView protein in InterPro
IPR016197, Chromo-like_dom_sf
IPR008676, MRG
IPR038217, MRG_C_sf
IPR026541, MRG_dom
IPR025995, Tudor-knot
PANTHERiPTHR10880, PTHR10880, 1 hit
PfamiView protein in Pfam
PF05712, MRG, 1 hit
PF11717, Tudor-knot, 1 hit
PIRSFiPIRSF038133, HAT_Nua4_EAF3/MRG15, 1 hit
SUPFAMiSSF54160, SSF54160, 1 hit
PROSITEiView protein in PROSITE
PS51640, MRG, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMRG1_CAEEL
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A7DTF0
Secondary accession number(s): Q9XWW2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 2, 2020
Last sequence update: September 11, 2007
Last modified: June 2, 2021
This is version 109 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
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