UniProtKB - A6ZIE2 (A6ZIE2_HUMAN)
Protein
MUC1-CT
Gene
MUC1
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Recommended name: MUC1-CTARBA annotationAlternative name(s): Mucin-1ARBA annotation Mucin-1 subunit alphaARBA annotation Mucin-1 subunit betaARBA annotation |
Gene namesi | Name:MUC1Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Subcellular locationi
Plasma membrane
- Apical cell membrane ARBA annotation; Single-pass type I membrane protein ARBA annotation
- Cell membrane ARBA annotation; Single-pass type I membrane protein ARBA annotation
Nucleus
- Nucleus ARBA annotation
Other locations
- Cytoplasm ARBA annotation
- Membrane ARBA annotation; Single-pass type I membrane protein ARBA annotation
Nucleus
- nucleus Source: UniProtKB-SubCell
Plasma Membrane
- apical plasma membrane Source: UniProtKB-SubCell
Other locations
- cytoplasm Source: UniProtKB-SubCell
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 119 – 144 | HelicalSequence analysisAdd BLAST | 26 |
Keywords - Cellular componenti
Cell membraneARBA annotation, CytoplasmARBA annotation, Membrane, NucleusARBA annotationPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 23 | Sequence analysisAdd BLAST | 23 | |
ChainiPRO_5002705371 | 24 – 215 | MUC1-CTSequence analysisAdd BLAST | 192 |
Keywords - PTMi
Autocatalytic cleavageARBA annotation, Lipoprotein, PalmitateARBA annotation, PhosphoproteinARBA annotationProteomic databases
MaxQBi | A6ZIE2 |
PeptideAtlasi | A6ZIE2 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 1 – 108 | SEAInterPro annotationAdd BLAST | 108 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 25 – 51 | DisorderedSequence analysisAdd BLAST | 27 | |
Regioni | 174 – 197 | DisorderedSequence analysisAdd BLAST | 24 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 177 – 197 | PolarSequence analysisAdd BLAST | 21 |
Keywords - Domaini
SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisFamily and domain databases
InterProi | View protein in InterPro IPR023217, Mucin-1 IPR000082, SEA_dom IPR036364, SEA_dom_sf |
PANTHERi | PTHR10006, PTHR10006, 2 hits |
SUPFAMi | SSF82671, SSF82671, 1 hit |
PROSITEi | View protein in PROSITE PS50024, SEA, 1 hit |
i Sequence
Sequence statusi: Complete.
A6ZIE2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTPGTQSPFF LLLLLTVLTV VTGSGHASST PGGEKETSAT QRSSVPSSTE
60 70 80 90 100
KNAFRPGSVV VQLTLAFREG TINVHDVETQ FNQYKTEAAS RYNLTISDVS
110 120 130 140 150
VSDVPFPFSA QSGAGVPGWG IALLVLVCVL VALAIVYLIA LAVCQCRRKN
160 170 180 190 200
YGQLDIFPAR DTYHPMSEYP TYHTHGRYVP PSSTDRSPYE KVSAGNGGSS
210
LSYTNPAVAA TSANL
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | EF670714 mRNA Translation: ABS01301.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | EF670714 mRNA Translation: ABS01301.1 |
3D structure databases
SMRi | A6ZIE2 |
ModBasei | Search... |
Proteomic databases
MaxQBi | A6ZIE2 |
PeptideAtlasi | A6ZIE2 |
Miscellaneous databases
ChiTaRSi | MUC1, human |
Family and domain databases
InterProi | View protein in InterPro IPR023217, Mucin-1 IPR000082, SEA_dom IPR036364, SEA_dom_sf |
PANTHERi | PTHR10006, PTHR10006, 2 hits |
SUPFAMi | SSF82671, SSF82671, 1 hit |
PROSITEi | View protein in PROSITE PS50024, SEA, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A6ZIE2_HUMAN | |
Accessioni | A6ZIE2Primary (citable) accession number: A6ZIE2 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | August 21, 2007 |
Last sequence update: | August 21, 2007 | |
Last modified: | October 7, 2020 | |
This is version 63 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |