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Protein

Ribosomal RNA large subunit methyltransferase F

Gene

rlmF

Organism
Marinomonas sp. (strain MWYL1)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Specifically methylates the adenine in position 1618 of 23S rRNA.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + adenine(1618) in 23S rRNA = S-adenosyl-L-homocysteine + rRNA containing N6-methyladenine(1618) in 23S rRNA.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionMethyltransferase, Transferase
Biological processrRNA processing
LigandS-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciMSP400668:G1G9E-4210-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosomal RNA large subunit methyltransferase FUniRule annotation (EC:2.1.1.181UniRule annotation)
Alternative name(s):
23S rRNA mA1618 methyltransferaseUniRule annotation
rRNA adenine N-6-methyltransferaseUniRule annotation
Gene namesi
Name:rlmFUniRule annotation
Ordered Locus Names:Mmwyl1_4062
OrganismiMarinomonas sp. (strain MWYL1)
Taxonomic identifieri400668 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaOceanospirillalesOceanospirillaceaeMarinomonas
Proteomesi
  • UP000001113 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003499201 – 327Ribosomal RNA large subunit methyltransferase FAdd BLAST327

Interactioni

Protein-protein interaction databases

STRINGi400668.Mmwyl1_4062

Structurei

3D structure databases

ProteinModelPortaliA6W2M9
SMRiA6W2M9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the methyltransferase superfamily. METTL16/RlmF family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105EBA Bacteria
COG3129 LUCA
HOGENOMiHOG000218605
KOiK06970
OMAiTEFHQGH
OrthoDBiPOG091H05H4

Family and domain databases

HAMAPiMF_01848 23SrRNA_methyltr_F, 1 hit
InterProiView protein in InterPro
IPR016909 rRNA_lsu_MeTfrase_F
IPR010286 rRNA_lsu_MeTfrase_F-like
IPR029063 SAM-dependent_MTases
PANTHERiPTHR13393 PTHR13393, 1 hit
PfamiView protein in Pfam
PF05971 Methyltransf_10, 1 hit
PIRSFiPIRSF029038 Mtase_YbiN_prd, 1 hit
SUPFAMiSSF53335 SSF53335, 1 hit

Sequencei

Sequence statusi: Complete.

A6W2M9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVLKSKNTKS KRTNKLELHP RNPHRARYDF ALLADSCPEL SGFIQLNQYG
60 70 80 90 100
NESVDFANPN AVKTLNRALL NHFYGVAFWD IPPGYLCPPI PGRADYIHYL
110 120 130 140 150
ADLLAASNLG VIPRGKGVKV LDVGVGANCV YPIIGHQEYG WQFVGSDVNP
160 170 180 190 200
VAVATCDTIV KSNPCLKGAI SARLQTQSAK LFDGVWKEKD RFDLTLCNPP
210 220 230 240 250
FHTSESAMID ESQRKWRGVK GKKTTTQKPV LNFGGTAAEL WCDGGEAGFV
260 270 280 290 300
SRMVKESVQY ADRCFWFTSL VARQGNLDAI YRTLKDVGAR QVKTIEMAQG
310 320
QKISRFVAWS FLGDDQIDYW KDNYWQN
Length:327
Mass (Da):36,607
Last modified:August 21, 2007 - v1
Checksum:iDC63AB9BADFF8C02
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000749 Genomic DNA Translation: ABR72958.1
RefSeqiWP_012071723.1, NC_009654.1

Genome annotation databases

EnsemblBacteriaiABR72958; ABR72958; Mmwyl1_4062
KEGGimmw:Mmwyl1_4062

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000749 Genomic DNA Translation: ABR72958.1
RefSeqiWP_012071723.1, NC_009654.1

3D structure databases

ProteinModelPortaliA6W2M9
SMRiA6W2M9
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi400668.Mmwyl1_4062

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABR72958; ABR72958; Mmwyl1_4062
KEGGimmw:Mmwyl1_4062

Phylogenomic databases

eggNOGiENOG4105EBA Bacteria
COG3129 LUCA
HOGENOMiHOG000218605
KOiK06970
OMAiTEFHQGH
OrthoDBiPOG091H05H4

Enzyme and pathway databases

BioCyciMSP400668:G1G9E-4210-MONOMER

Family and domain databases

HAMAPiMF_01848 23SrRNA_methyltr_F, 1 hit
InterProiView protein in InterPro
IPR016909 rRNA_lsu_MeTfrase_F
IPR010286 rRNA_lsu_MeTfrase_F-like
IPR029063 SAM-dependent_MTases
PANTHERiPTHR13393 PTHR13393, 1 hit
PfamiView protein in Pfam
PF05971 Methyltransf_10, 1 hit
PIRSFiPIRSF029038 Mtase_YbiN_prd, 1 hit
SUPFAMiSSF53335 SSF53335, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiRLMF_MARMS
AccessioniPrimary (citable) accession number: A6W2M9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: August 21, 2007
Last modified: February 28, 2018
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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