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Protein

UvrABC system protein C

Gene

uvrC

Organism
Actinobacillus succinogenes (strain ATCC 55618 / 130Z)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionExcision nuclease
Biological processDNA damage, DNA excision, DNA repair, SOS response

Enzyme and pathway databases

BioCyciASUC339671:G1G9D-1805-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
UvrABC system protein CUniRule annotation
Short name:
Protein UvrCUniRule annotation
Alternative name(s):
Excinuclease ABC subunit CUniRule annotation
Gene namesi
Name:uvrCUniRule annotation
Ordered Locus Names:Asuc_1724
OrganismiActinobacillus succinogenes (strain ATCC 55618 / 130Z)
Taxonomic identifieri339671 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeActinobacillus
Proteomesi
  • UP000001114 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000777471 – 608UvrABC system protein CAdd BLAST608

Proteomic databases

PRIDEiA6VQ29

Interactioni

Subunit structurei

Interacts with UvrB in an incision complex.UniRule annotation

Protein-protein interaction databases

STRINGi339671.Asuc_1724

Structurei

3D structure databases

ProteinModelPortaliA6VQ29
SMRiA6VQ29
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini13 – 91GIY-YIGUniRule annotationAdd BLAST79
Domaini201 – 236UVRUniRule annotationAdd BLAST36

Sequence similaritiesi

Belongs to the UvrC family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CII Bacteria
COG0322 LUCA
HOGENOMiHOG000279961
KOiK03703
OMAiLFPIRQC
OrthoDBiPOG091H01BS

Family and domain databases

Gene3Di3.30.420.340, 1 hit
3.40.1440.10, 1 hit
HAMAPiMF_00203 UvrC, 1 hit
InterProiView protein in InterPro
IPR000305 GIY-YIG_endonuc
IPR035901 GIY-YIG_endonuc_sf
IPR003583 Hlx-hairpin-Hlx_DNA-bd_motif
IPR010994 RuvA_2-like
IPR001943 UVR_dom
IPR036876 UVR_dom_sf
IPR004791 UvrC
IPR001162 UvrC_homol_region
IPR038476 UvrC_homol_region_sf
PfamiView protein in Pfam
PF01541 GIY-YIG, 1 hit
PF02151 UVR, 1 hit
PF08459 UvrC_HhH_N, 1 hit
SMARTiView protein in SMART
SM00465 GIYc, 1 hit
SM00278 HhH1, 2 hits
SUPFAMiSSF46600 SSF46600, 1 hit
SSF47781 SSF47781, 1 hit
SSF82771 SSF82771, 1 hit
TIGRFAMsiTIGR00194 uvrC, 1 hit
PROSITEiView protein in PROSITE
PS50164 GIY_YIG, 1 hit
PS50151 UVR, 1 hit
PS50165 UVRC, 1 hit

Sequencei

Sequence statusi: Complete.

A6VQ29-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFDSKAFLKN VPHDPGVYRM FDKTDTVIYV GKAKDLKKRL SSYFRPNLSS
60 70 80 90 100
KKTEALVASI TRIETTITTS ETEALLLEHN YIKTFQPRYN VLLRDDKSYP
110 120 130 140 150
YILLTKERHP RIAAYRGAKK IQGEYFGPYP HAGAVRETLS LLQKLFPIRQ
160 170 180 190 200
CENSVYKNRS RPCLQYQIGR CCAPCVAGYV TDEEYQAQVE YARLFLQGKD
210 220 230 240 250
QQVLDHLIAK METASRALDF ENAARFRDQI QAVRAVIEKQ FVSNDRLDDM
260 270 280 290 300
DIISIAYRHG VACVQVLFIR QGKVLGNRSY FPKVPANTDL SELTATFVGQ
310 320 330 340 350
FYLQAHQGRT VPNSIVVDHK LEAKEEIEQL LSEQAGRKVS IQDNAKGSKS
360 370 380 390 400
KYLSLAQMNA KAALTLKLKE STLISERYRA LRELLDMDKI NRMECFDISH
410 420 430 440 450
TMGEQTIASC VVFNDAGPFK SEYRRFNIEG ITGGDDYAAM EQALKKRYDR
460 470 480 490 500
DLTPEKIPDI IFIDGGKGQL NRALKAFGEL NVKWDKNRPH LIGIAKGVDR
510 520 530 540 550
RAGQETLILS KTGREVNLDP DNLALHLIQH IRDESHNHAI SGHRKKRQKA
560 570 580 590 600
FTQSGLETIE GVGPKRRQAL LKYLGGMQGV KNATLEEIAS VPGISRALAE

IIFETLKH
Length:608
Mass (Da):68,933
Last modified:August 21, 2007 - v1
Checksum:iDAC7C657B4438B8B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000746 Genomic DNA Translation: ABR75076.1
RefSeqiWP_012073453.1, NC_009655.1

Genome annotation databases

EnsemblBacteriaiABR75076; ABR75076; Asuc_1724
KEGGiasu:Asuc_1724

Similar proteinsi

Entry informationi

Entry nameiUVRC_ACTSZ
AccessioniPrimary (citable) accession number: A6VQ29
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: August 21, 2007
Last modified: May 23, 2018
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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