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Protein

tRNA pseudouridine synthase D

Gene

truD

Organism
Pseudomonas aeruginosa (strain PA7)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(13) = tRNA pseudouridine(13).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei84NucleophileUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processtRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase DUniRule annotation (EC:5.4.99.27UniRule annotation)
Alternative name(s):
tRNA pseudouridine(13) synthaseUniRule annotation
tRNA pseudouridylate synthase DUniRule annotation
tRNA-uridine isomerase DUniRule annotation
Gene namesi
Name:truDUniRule annotation
Ordered Locus Names:PSPA7_1513
OrganismiPseudomonas aeruginosa (strain PA7)
Taxonomic identifieri381754 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000001582 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000847541 – 355tRNA pseudouridine synthase DAdd BLAST355

Proteomic databases

PRIDEiA6V1G2

Structurei

3D structure databases

ProteinModelPortaliA6V1G2
SMRiA6V1G2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini160 – 306TRUDUniRule annotationAdd BLAST147

Sequence similaritiesi

Belongs to the pseudouridine synthase TruD family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000224848
KOiK06176
OMAiGNRFFMR

Family and domain databases

HAMAPiMF_01082 TruD, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR001656 PsdUridine_synth_TruD
IPR020119 PsdUridine_synth_TruD_CS
IPR011760 PsdUridine_synth_TruD_insert
PANTHERiPTHR13326 PTHR13326, 2 hits
PfamiView protein in Pfam
PF01142 TruD, 2 hits
SUPFAMiSSF55120 SSF55120, 1 hit
PROSITEiView protein in PROSITE
PS50984 TRUD, 1 hit
PS01268 UPF0024, 1 hit

Sequencei

Sequence statusi: Complete.

A6V1G2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSVLGELDLL GPRAHGAACG EAVLKAVAED FQVDEVLDIP LSGEGEHLWL
60 70 80 90 100
WVEKRGLNTE EAARRLGRAA GVQQKHVSYA GLKDRQALTR QWFSLHLPGK
110 120 130 140 150
ADPDLGAAEG EDLRILRRTR HSRKLQRGAH AANGFTLRLT ALRAERVLLD
160 170 180 190 200
ARLERIAAVG VPNYFGLQRF GHGGGNLVDA RSCAEQDLLP ANRNLRSRFL
210 220 230 240 250
SAGRSYLFNR LLAERVAEGS WNRAAVGDLL AFTDSRSFFL AGEEECRDAR
260 270 280 290 300
LAALDLHPTG PLWGEGDPPS GAGVLERELA LAGSEPALCR WLAKAGMAHE
310 320 330 340 350
RRILRLPIQG LAWHYPEPDV LQLEFVLPAG CFATVVVREI LDLVPTGQTE

NPCAY
Length:355
Mass (Da):38,889
Last modified:August 21, 2007 - v1
Checksum:i656381A0A32D9B4B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000744 Genomic DNA Translation: ABR84456.1
RefSeqiWP_012074705.1, NC_009656.1

Genome annotation databases

EnsemblBacteriaiABR84456; ABR84456; PSPA7_1513
KEGGipap:PSPA7_1513

Similar proteinsi

Entry informationi

Entry nameiTRUD_PSEA7
AccessioniPrimary (citable) accession number: A6V1G2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: August 21, 2007
Last modified: September 12, 2018
This is version 65 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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