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Entry version 59 (31 Jul 2019)
Sequence version 1 (21 Aug 2007)
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Protein
Submitted name:

Ti-type conjugative transfer relaxase TraA

Gene

Smed_5393

Organism
Sinorhizobium medicae (strain WSM419) (Ensifer medicae)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
SMED366394:GJAL-5368-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Ti-type conjugative transfer relaxase TraAImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:Smed_5393Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates if the gene coding for the protein originates from the hydrogenosome, the mitochondrion, the nucleomorph, different plastids or a plasmid. The absence of this section means that the gene is located in one of the main chromosomal element(s).<p><a href='/help/encoded_on' target='_top'>More...</a></p>Encoded oniPlasmid pSMED02Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSinorhizobium medicae (strain WSM419) (Ensifer medicae)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri366394 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeSinorhizobium/Ensifer groupSinorhizobium
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001108 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Plasmid pSMED02

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
366394.Smed_5393

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini17 – 243MobA_MobLInterPro annotationAdd BLAST227
Domaini692 – 731UvrD_C_2InterPro annotationAdd BLAST40
Domaini858 – 954Bep_C_terminalInterPro annotationAdd BLAST97

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1080 – 1102DisorderedSequence analysisAdd BLAST23

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili241 – 268Sequence analysisAdd BLAST28

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

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HOGENOMi
HOG000138087

Identification of Orthologs from Complete Genome Data

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OMAi
DGMELHY

Database of Orthologous Groups

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OrthoDBi
961809at2

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR041533 Bep_BID
IPR005053 MobA_MobL
IPR027417 P-loop_NTPase
IPR014136 TraA_Ti
IPR027785 UvrD-like_helicase_C

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF17841 Bep_C_terminal, 1 hit
PF03389 MobA_MobL, 1 hit
PF13538 UvrD_C_2, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540 SSF52540, 2 hits

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR02768 TraA_Ti, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A6UKI1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAVPHFSVSL ITRGSGRSAV LSAAYRHCAK MAYQREARTI DYTRKTGLLH
60 70 80 90 100
EEFVIPDNAP EWLQSMITDR SVSDAAEAFW NKVEDFEKRS DAQLAKEVTI
110 120 130 140 150
ALPIELTSAQ NIALVRDFVE QHISAKGMVA DWVYHDAPGN PHVHLMTTLR
160 170 180 190 200
PLTQQGFGAK KVAVLGPDGY PIRNDAGKIV YELWAGSLDD FNALRDGWFA
210 220 230 240 250
CQNRHLTLAG LDIRIDGRSF EKQGIELAPT LHLGAGTKAI ERKATAEAKT
260 270 280 290 300
LSLERLQLQE ELRNENARRI QRRPEIVLDL ITRERSVFDE RDVAKILHRY
310 320 330 340 350
VDDPAVFRSL MARILQSPET LQLERERTAF ATGIRAPAKY TTRALIRLEA
360 370 380 390 400
EMANRAIWLS RQSSHRLREA VLEATLARHS RLSDEQKTAI EHVAKAGRIA
410 420 430 440 450
AVIGRAGAGK TTMMKAAREA WEAAGYRVVG GALAGKAAEG LEKEAGIISR
460 470 480 490 500
TLSAWELRWS QGRNQLDAGT VFILDEAGMV SSRQMACFIE AATRTGAKLV
510 520 530 540 550
LVGDPEQLQP IEAGAAFRAI ADRIGYAELE TIYRQREQWM RDASLDLARG
560 570 580 590 600
NVGKAVEAYR ANGRMIGAEL KAEAVRNLVA DWNRDYDPTK TTLILAHLRR
610 620 630 640 650
DVRMLNEMAR SKLVERGIVG EGFAFRTADG NRNFAAGDQI VFLKNEGSLG
660 670 680 690 700
VKNGMLGKIV EASPNRVVAE IGAGEHHRQV IIEQRFYNNL DHGYATTIHK
710 720 730 740 750
SQGATVDRVK VLASLSLDRH LVYVAMTRHR DNLDVYYGAR SFARAGGLIQ
760 770 780 790 800
VLSRKNSKET TLDYEKATFY RQALRFAEAR GLHLLNVART ITRDRLAWTA
810 820 830 840 850
RQSSRLAGLA HRLVRIGRKL GLAAGTNPIN SQNSKETRPM VAGITTYPES
860 870 880 890 900
VEQAVADKLA ADPGLKKQWD DVSTRFHLVY AHPAAAFKAV NIDVMLKDET
910 920 930 940 950
VAKATLSKIA KQPDSYGALK GKTGLLASRA DRQDRQRAER NVPALVQSLD
960 970 980 990 1000
GYMRQRGSAE RRYRAEELEA RRKVAIDIPA LSPGARQILE RVRDAIDRND
1010 1020 1030 1040 1050
LSAALEFARA DRHVKAELDG FANAVDARFG KRTFLPLSAS DTNGDTFTSV
1060 1070 1080 1090 1100
TAGMNPGQRL EVESAWKAMR TVQQLSAHER TTEALKHSET LRLSKGQGLS

LR
Length:1,102
Mass (Da):122,388
Last modified:August 21, 2007 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD0F9D6D3B6A138CA
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CP000740 Genomic DNA Translation: ABR64161.1

NCBI Reference Sequences

More...
RefSeqi
WP_011970270.1, NC_009621.1
YP_001314094.1, NC_009621.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

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EnsemblBacteriai
ABR64161; ABR64161; Smed_5393

Database of genes from NCBI RefSeq genomes

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GeneIDi
5319695

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
smd:Smed_5393

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|366394.8.peg.1885

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000740 Genomic DNA Translation: ABR64161.1
RefSeqiWP_011970270.1, NC_009621.1
YP_001314094.1, NC_009621.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi366394.Smed_5393

Genome annotation databases

EnsemblBacteriaiABR64161; ABR64161; Smed_5393
GeneIDi5319695
KEGGismd:Smed_5393
PATRICifig|366394.8.peg.1885

Phylogenomic databases

HOGENOMiHOG000138087
OMAiDGMELHY
OrthoDBi961809at2

Enzyme and pathway databases

BioCyciSMED366394:GJAL-5368-MONOMER

Family and domain databases

InterProiView protein in InterPro
IPR041533 Bep_BID
IPR005053 MobA_MobL
IPR027417 P-loop_NTPase
IPR014136 TraA_Ti
IPR027785 UvrD-like_helicase_C
PfamiView protein in Pfam
PF17841 Bep_C_terminal, 1 hit
PF03389 MobA_MobL, 1 hit
PF13538 UvrD_C_2, 1 hit
SUPFAMiSSF52540 SSF52540, 2 hits
TIGRFAMsiTIGR02768 TraA_Ti, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA6UKI1_SINMW
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A6UKI1
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: August 21, 2007
Last sequence update: August 21, 2007
Last modified: July 31, 2019
This is version 59 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteomeImported, PlasmidImported
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