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Protein

Anhydro-N-acetylmuramic acid kinase

Gene

anmK

Organism
Sinorhizobium medicae (strain WSM419) (Ensifer medicae)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.UniRule annotation

Catalytic activityi

ATP + 1,6-anhydro-N-acetyl-beta-muramate + H2O = ADP + N-acetylmuramate 6-phosphate.UniRule annotation

Pathwayi: 1,6-anhydro-N-acetylmuramate degradation

This protein is involved in the pathway 1,6-anhydro-N-acetylmuramate degradation, which is part of Amino-sugar metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway 1,6-anhydro-N-acetylmuramate degradation and in Amino-sugar metabolism.

Pathwayi: peptidoglycan recycling

This protein is involved in the pathway peptidoglycan recycling, which is part of Cell wall biogenesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway peptidoglycan recycling and in Cell wall biogenesis.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi13 – 20ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Transferase
Biological processCarbohydrate metabolism
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00343
UPA00544

Names & Taxonomyi

Protein namesi
Recommended name:
Anhydro-N-acetylmuramic acid kinaseUniRule annotation (EC:2.7.1.170UniRule annotation)
Alternative name(s):
AnhMurNAc kinaseUniRule annotation
Gene namesi
Name:anmKUniRule annotation
Ordered Locus Names:Smed_1472
OrganismiSinorhizobium medicae (strain WSM419) (Ensifer medicae)
Taxonomic identifieri366394 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeSinorhizobium/Ensifer groupSinorhizobium
Proteomesi
  • UP000001108 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000673701 – 382Anhydro-N-acetylmuramic acid kinaseAdd BLAST382

Proteomic databases

PRIDEiA6U9I7

Interactioni

Protein-protein interaction databases

STRINGi366394.Smed_1472

Structurei

3D structure databases

ProteinModelPortaliA6U9I7
SMRiA6U9I7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the anhydro-N-acetylmuramic acid kinase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105ED7 Bacteria
COG2377 LUCA
HOGENOMiHOG000256308
KOiK09001
OMAiHGQTVYH
OrthoDBiPOG091H05JF

Family and domain databases

HAMAPiMF_01270 AnhMurNAc_kinase, 1 hit
InterProiView protein in InterPro
IPR005338 Anhydro_N_Ac-Mur_kinase
PANTHERiPTHR30605 PTHR30605, 1 hit
PfamiView protein in Pfam
PF03702 AnmK, 1 hit

Sequencei

Sequence statusi: Complete.

A6U9I7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKTVTAIGL MSGTSMDGID VALLRTDGET IVDRGPSAGY TYDPAFRARL
60 70 80 90 100
KTGLDDARSI VKREERPGTL ADLEHELTLR HADAVRGFLH QNNILSESVD
110 120 130 140 150
VVGFHGQTVL HRPDEALTVQ LGDGDLLAQE TGIDVVYDMR ANDMAHGGQG
160 170 180 190 200
APLIPAYHAA LAHELSKNGE IVAPAVFVNI GGISNLTFIG WRDEIVAYDS
210 220 230 240 250
GPGNTLIDQW VEAHAGIPFD QGGMIASEGS VMRELAESYL SHPFFSAEKR
260 270 280 290 300
RSLDRNDFAP PSGEAASLED GARTLAHVTA AAIIRSAQHL PARPETYIVC
310 320 330 340 350
GGGRLNPVIM RDLHMLAEAE GARVVAAEAL RLNGDSMEAE AWAYLAVRSR
360 370 380
CGLPLTYPGT TGVSRPVSGG RLARKPSRAE TA
Length:382
Mass (Da):40,778
Last modified:August 21, 2007 - v1
Checksum:iEA6A888F52DDC4B3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000738 Genomic DNA Translation: ABR60317.1
RefSeqiWP_011975627.1, NC_009636.1
YP_001327152.1, NC_009636.1

Genome annotation databases

EnsemblBacteriaiABR60317; ABR60317; Smed_1472
GeneIDi5322330
KEGGismd:Smed_1472
PATRICifig|366394.8.peg.4605

Similar proteinsi

Entry informationi

Entry nameiANMK_SINMW
AccessioniPrimary (citable) accession number: A6U9I7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: August 21, 2007
Last modified: May 23, 2018
This is version 58 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

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