UniProtKB - A6THR5 (A6THR5_KLEP7)
Protein
Autoinducer 2-binding protein LsrB
Gene
KPN_04753
Organism
Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)
Status
Names & Taxonomyi
Protein namesi | Recommended name: Autoinducer 2-binding protein LsrBARBA annotation |
Gene namesi | ORF Names:KPN_04753Imported |
Organismi | Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)Imported |
Taxonomic identifieri | 272620 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Klebsiella › |
Proteomesi |
|
Subcellular locationi
- Periplasm ARBA annotation
GO - Cellular componenti
- ATP-binding cassette (ABC) transporter complex Source: InterPro
- periplasmic space Source: UniProtKB-SubCell
Keywords - Cellular componenti
PeriplasmARBA annotationPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 26 | Sequence analysisAdd BLAST | 26 | |
ChainiPRO_5002702202 | 27 – 327 | Autoinducer 2-binding protein LsrBSequence analysisAdd BLAST | 301 |
Interactioni
Subunit structurei
The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).
ARBA annotationStructurei
3D structure databases
SMRi | A6THR5 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | A6THR5 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 35 – 287 | Peripla_BP_4InterPro annotationAdd BLAST | 253 |
Sequence similaritiesi
Belongs to the bacterial solute-binding protein 2 family.ARBA annotation
Keywords - Domaini
SignalSequence analysisPhylogenomic databases
HOGENOMi | CLU_037628_3_0_6 |
OMAi | CVVSACM |
Family and domain databases
CDDi | cd06302, PBP1_LsrB_Quorum_Sensing, 1 hit |
InterProi | View protein in InterPro IPR030159, LsrB IPR028082, Peripla_BP_I IPR025997, SBP_2_dom |
Pfami | View protein in Pfam PF13407, Peripla_BP_4, 1 hit |
SUPFAMi | SSF53822, SSF53822, 1 hit |
i Sequence
Sequence statusi: Complete.
A6THR5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MHKRLVVNIF SSLLLGAALI SAPVYAAEKT VVNISKVDGM PWFNRMGEGV
60 70 80 90 100
VQAGKEFNLN ASQVGPSSTD APQQVKIIED LIARKVDAIT IVPNDANVLE
110 120 130 140 150
PVFKKARDAG IVVLTNESPG QPSANWDVEI IDNEKFAAEY VEHMAKRMGG
160 170 180 190 200
KGGYVIYVGS LTVPQHNLWA DLLVKYQKEH YPDMHEVTRR MPVAESVDDS
210 220 230 240 250
RRTTLDLMKT YPDLKAVVSF GSNGPIGAGR AVKEKRAKNK VAVYGMMIPS
260 270 280 290 300
QAASLIKSGD ITEGITYDPA TAGYALAAVA STLLNGKTIE PGFELKELGK
310 320
AEVDSDKHII RFHKVLLVNK DNIDSLY
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP000647 Genomic DNA Translation: ABR80099.1 |
RefSeqi | WP_002887349.1, NC_009648.1 |
Genome annotation databases
EnsemblBacteriai | ABR80099; ABR80099; KPN_04753 |
GeneIDi | 56999821 |
KEGGi | kpn:KPN_04753 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP000647 Genomic DNA Translation: ABR80099.1 |
RefSeqi | WP_002887349.1, NC_009648.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
3D02 | X-ray | 1.30 | A | 26-327 | [»] | |
SMRi | A6THR5 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Genome annotation databases
EnsemblBacteriai | ABR80099; ABR80099; KPN_04753 |
GeneIDi | 56999821 |
KEGGi | kpn:KPN_04753 |
Phylogenomic databases
HOGENOMi | CLU_037628_3_0_6 |
OMAi | CVVSACM |
Enzyme and pathway databases
BioCyci | KPNE272620:G1G8J-5116-MONOMER |
Miscellaneous databases
EvolutionaryTracei | A6THR5 |
Family and domain databases
CDDi | cd06302, PBP1_LsrB_Quorum_Sensing, 1 hit |
InterProi | View protein in InterPro IPR030159, LsrB IPR028082, Peripla_BP_I IPR025997, SBP_2_dom |
Pfami | View protein in Pfam PF13407, Peripla_BP_4, 1 hit |
SUPFAMi | SSF53822, SSF53822, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A6THR5_KLEP7 | |
Accessioni | A6THR5Primary (citable) accession number: A6THR5 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | August 21, 2007 |
Last sequence update: | August 21, 2007 | |
Last modified: | February 10, 2021 | |
This is version 72 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |