UniProtKB - A6T4X2 (EFTS_KLEP7)
Protein
Elongation factor Ts
Gene
tsf
Organism
Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)
Status
Functioni
Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.UniRule annotation
GO - Molecular functioni
- translation elongation factor activity Source: UniProtKB-UniRule
Keywordsi
Molecular function | Elongation factor |
Biological process | Protein biosynthesis |
Enzyme and pathway databases
BioCyci | KPNE272620:G1G8J-192-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: Elongation factor TsUniRule annotationShort name: EF-TsUniRule annotation |
Gene namesi | Name:tsfUniRule annotation Ordered Locus Names:KPN78578_01820 ORF Names:KPN_00183 |
Organismi | Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578) |
Taxonomic identifieri | 272620 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Klebsiella › |
Proteomesi |
|
Subcellular locationi
Cytoplasm and Cytosol
- Cytoplasm UniRule annotation
Other locations
- cytoplasm Source: UniProtKB-SubCell
Keywords - Cellular componenti
CytoplasmPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_1000006110 | 1 – 283 | Elongation factor TsAdd BLAST | 283 |
Proteomic databases
jPOSTi | A6T4X2 |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 80 – 83 | Involved in Mg(2+) ion dislocation from EF-TuUniRule annotation | 4 |
Sequence similaritiesi
Belongs to the EF-Ts family.UniRule annotation
Phylogenomic databases
HOGENOMi | CLU_047155_0_2_6 |
OMAi | DAGMMDC |
Family and domain databases
Gene3Di | 3.30.479.20, 1 hit |
HAMAPi | MF_00050, EF_Ts, 1 hit |
InterProi | View protein in InterPro IPR036402, EF-Ts_dimer_sf IPR001816, Transl_elong_EFTs/EF1B IPR014039, Transl_elong_EFTs/EF1B_dimer IPR018101, Transl_elong_Ts_CS IPR009060, UBA-like_sf |
PANTHERi | PTHR11741, PTHR11741, 1 hit |
Pfami | View protein in Pfam PF00889, EF_TS, 1 hit |
SUPFAMi | SSF46934, SSF46934, 1 hit SSF54713, SSF54713, 2 hits |
TIGRFAMsi | TIGR00116, tsf, 1 hit |
PROSITEi | View protein in PROSITE PS01126, EF_TS_1, 1 hit PS01127, EF_TS_2, 1 hit |
i Sequence
Sequence statusi: Complete.
A6T4X2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAEITASLVK ELRERTGAGM MDCKKALTEA NGDIELAIEN MRKSGAIKAA
60 70 80 90 100
KKAGNVAADG VIKTKIEGNY GYILEVNCQT DFVAKDGGFQ AFADKVLDAA
110 120 130 140 150
VAGKISDVEV LKAQFEEERV ALVAKIGENI NIRRIAVLEG DVLGSYQHGA
160 170 180 190 200
RIGVLVAAKG ADEELVKQLA MHVAASKPEF VKPEDVSAEV VEKEYQVQLD
210 220 230 240 250
IAMQSGKPKE IAEKMVEGRM KKFTGEVSLT GQPFVMEPSK SVGQLLKEHN
260 270 280
ADVTGFIRFE VGEGIEKVET DFAAEVAAMS KQS
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP000647 Genomic DNA Translation: ABR75643.1 |
RefSeqi | WP_004151930.1, NC_009648.1 |
Genome annotation databases
EnsemblBacteriai | ABR75643; ABR75643; KPN_00183 |
GeneIDi | 56981385 |
KEGGi | kpn:KPN_00183 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP000647 Genomic DNA Translation: ABR75643.1 |
RefSeqi | WP_004151930.1, NC_009648.1 |
3D structure databases
SMRi | A6T4X2 |
ModBasei | Search... |
Proteomic databases
jPOSTi | A6T4X2 |
Genome annotation databases
EnsemblBacteriai | ABR75643; ABR75643; KPN_00183 |
GeneIDi | 56981385 |
KEGGi | kpn:KPN_00183 |
Phylogenomic databases
HOGENOMi | CLU_047155_0_2_6 |
OMAi | DAGMMDC |
Enzyme and pathway databases
BioCyci | KPNE272620:G1G8J-192-MONOMER |
Family and domain databases
Gene3Di | 3.30.479.20, 1 hit |
HAMAPi | MF_00050, EF_Ts, 1 hit |
InterProi | View protein in InterPro IPR036402, EF-Ts_dimer_sf IPR001816, Transl_elong_EFTs/EF1B IPR014039, Transl_elong_EFTs/EF1B_dimer IPR018101, Transl_elong_Ts_CS IPR009060, UBA-like_sf |
PANTHERi | PTHR11741, PTHR11741, 1 hit |
Pfami | View protein in Pfam PF00889, EF_TS, 1 hit |
SUPFAMi | SSF46934, SSF46934, 1 hit SSF54713, SSF54713, 2 hits |
TIGRFAMsi | TIGR00116, tsf, 1 hit |
PROSITEi | View protein in PROSITE PS01126, EF_TS_1, 1 hit PS01127, EF_TS_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | EFTS_KLEP7 | |
Accessioni | A6T4X2Primary (citable) accession number: A6T4X2 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | January 15, 2008 |
Last sequence update: | August 21, 2007 | |
Last modified: | February 10, 2021 | |
This is version 71 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families