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Entry version 74 (02 Jun 2021)
Sequence version 1 (21 Aug 2007)
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Protein

Dysferlin

Gene

DYSF

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Key calcium ion sensor involved in the Ca2+-triggered synaptic vesicle-plasma membrane fusion. Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress (By similarity).

By similarity

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Ca2+PROSITE-ProRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi18Calcium 1By similarity1
Metal bindingi19Calcium 1; via carbonyl oxygenBy similarity1
Metal bindingi21Calcium 1By similarity1
Metal bindingi40Calcium 1By similarity1
Metal bindingi411Calcium 2PROSITE-ProRule annotation1
Metal bindingi411Calcium 3PROSITE-ProRule annotation1
Metal bindingi419Calcium 2PROSITE-ProRule annotation1
Metal bindingi467Calcium 2PROSITE-ProRule annotation1
Metal bindingi467Calcium 3PROSITE-ProRule annotation1
Metal bindingi469Calcium 2PROSITE-ProRule annotation1
Metal bindingi469Calcium 3PROSITE-ProRule annotation1
Metal bindingi475Calcium 3PROSITE-ProRule annotation1
Metal bindingi1170Calcium 4PROSITE-ProRule annotation1
Metal bindingi1176Calcium 4PROSITE-ProRule annotation1
Metal bindingi1232Calcium 4PROSITE-ProRule annotation1
Metal bindingi1234Calcium 4PROSITE-ProRule annotation1
Metal bindingi1621Calcium 5PROSITE-ProRule annotation1
Metal bindingi1627Calcium 5PROSITE-ProRule annotation1
Metal bindingi1676Calcium 5PROSITE-ProRule annotation1
Metal bindingi1678Calcium 5PROSITE-ProRule annotation1
Metal bindingi1941Calcium 6PROSITE-ProRule annotation1
Metal bindingi1944Calcium 6PROSITE-ProRule annotation1
Metal bindingi1947Calcium 6PROSITE-ProRule annotation1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandCalcium, Lipid-binding, Metal-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Dysferlin
Alternative name(s):
Dystrophy-associated fer-1-like protein
Fer-1-like protein 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:DYSF
Synonyms:FER1L1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiBos taurus (Bovine)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9913 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaArtiodactylaRuminantiaPecoraBovidaeBovinaeBos
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000009136 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei2074 – 2094HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Cell membrane, Cytoplasmic vesicle, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003555601 – 2107DysferlinAdd BLAST2107

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei166PhosphothreonineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
A6QQP7

PeptideAtlas

More...
PeptideAtlasi
A6QQP7

PRoteomics IDEntifications database

More...
PRIDEi
A6QQP7

PTM databases

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
A6QQP7

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with CACNA1S, CAV3 and PARVB.

Interacts with ANXA1; the interaction is Ca2+- and injury state-dependent.

Interacts with ANXA2; the interaction is Ca2+- and injury state-dependent.

Interacts with AHNAK; the interaction is direct and Ca2+-independent.

Interacts with AHNAK2; the interaction is direct and Ca2+-independent.

Interacts with TRIM72/MG53; interaction is required for transport to sites of cell injury during repair patch formation (By similarity).

Interacts with RIPOR2; this interaction occurs during early myogenic differentiation (By similarity).

By similarity

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9913.ENSBTAP00000033077

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
A6QQP7

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1 – 101C2 1PROSITE-ProRule annotationAdd BLAST101
Domaini205 – 323C2 2PROSITE-ProRule annotationAdd BLAST119
Domaini362 – 498C2 3PROSITE-ProRule annotationAdd BLAST137
Domaini1138 – 1264C2 4PROSITE-ProRule annotationAdd BLAST127
Domaini1312 – 1440C2 5PROSITE-ProRule annotationAdd BLAST129
Domaini1588 – 1706C2 6PROSITE-ProRule annotationAdd BLAST119
Domaini1822 – 1970C2 7PROSITE-ProRule annotationAdd BLAST149

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni132 – 221DisorderedSequence analysisAdd BLAST90
Regioni2021 – 2044DisorderedSequence analysisAdd BLAST24

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi152 – 168Acidic residuesSequence analysisAdd BLAST17

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

All seven C2 domains associate with lipid membranes in a calcium-dependent manner. Domains C2 1 and 3 have the highest affinity for calcium, the C2 domain 1 seems to be largely unstructured in the absence of bound ligands (By similarity).By similarity

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the ferlin family.Curated

Keywords - Domaini

Repeat, Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1326, Eukaryota

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
A6QQP7

Database of Orthologous Groups

More...
OrthoDBi
20162at2759

Family and domain databases

Conserved Domains Database

More...
CDDi
cd08373, C2A_Ferlin, 1 hit
cd04011, C2B_Ferlin, 1 hit
cd04018, C2C_Ferlin, 1 hit
cd04017, C2D_Ferlin, 1 hit
cd04037, C2E_Ferlin, 1 hit
cd08374, C2F_Ferlin, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.150, 6 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000008, C2_dom
IPR035892, C2_domain_sf
IPR037726, C2A_Ferlin
IPR037720, C2B_Ferlin
IPR037722, C2C_Ferlin
IPR037723, C2D_Ferlin
IPR037724, C2E_Ferlin
IPR037725, C2F_Ferlin
IPR029998, Dysferlin
IPR012968, FerIin_dom
IPR037721, Ferlin
IPR012560, Ferlin_A-domain
IPR012561, Ferlin_B-domain
IPR032362, Ferlin_C
IPR006614, Peroxin/Ferlin

The PANTHER Classification System

More...
PANTHERi
PTHR12546, PTHR12546, 1 hit
PTHR12546:SF44, PTHR12546:SF44, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00168, C2, 7 hits
PF08165, FerA, 1 hit
PF08150, FerB, 1 hit
PF08151, FerI, 1 hit
PF16165, Ferlin_C, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00239, C2, 7 hits
SM00694, DysFC, 2 hits
SM00693, DysFN, 2 hits
SM01200, FerA, 1 hit
SM01201, FerB, 1 hit
SM01202, FerI, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50004, C2, 7 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A6QQP7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLRVFILYAE NVHTPDTDIS DAYCSAVFAG VKKRTKVIKN NVNPVWNEGF
60 70 80 90 100
EWDLKGIPLD QGSELLVVVK DHETMGRNRF LGEANIPLRE VLATPSLSAS
110 120 130 140 150
FNAPLLDTKK QPTGASLVLQ VSYTPLPGAV PTFPPLTPLE PSPTLPDMDT
160 170 180 190 200
VADTGGEEDT EDQGLTGDEA EPFLDQSGAL GPGAPSTPKK QPSHPPPYHP
210 220 230 240 250
GGGRKRSAPA PSKPLSDKPQ DFQIRVQVIK GRQLPGVNIK PVVKVTAAGQ
260 270 280 290 300
TKRTRIHKGN SPVFNETLFF NVFDSPAELF NEPIFITVVD SRSLRTDALI
310 320 330 340 350
GEFRLDVGSI YREPRHAYLR KWLLLSDPDD FSAGARGYLK ASLCVLGPGD
360 370 380 390 400
EAPLERKDPS EDKEDIESNL LRPIGVALRG AHFCLKVFRA EDLPQMDDAV
410 420 430 440 450
MDNVRQIFGF DSNKKNLVDP FVEVSFAGKM LCSKILEKTA NPQWNQSITL
460 470 480 490 500
PAMFPSMCEK MRIRVVDWDR LTHNDIVATT YLSMSKISAS GGEIEEEPAG
510 520 530 540 550
VVKPPPATEL DDHLGFLPTF GPCYINLYGS PREFTGFPDP YAELNTGKGE
560 570 580 590 600
GVAYRGRLLL SLETKLVERS EQKVEALSAD DILRVEKYLR RRKYSLFAAF
610 620 630 640 650
YSATMLQDVD DAVQFEVSIG NYGNKFDTTC LPLASTTQYS RAVFDGCHYY
660 670 680 690 700
YLPWGNVKPV VVLSSYWEDI RHRVEAQNQL LRIADQLEAG LEQVHLALKA
710 720 730 740 750
QCSDEDVDSL VAQLMDELIA GCSQPLGDVQ EMPSATHLDQ YLYQLRTRHL
760 770 780 790 800
SQITEAAQAL KLGHSELPAA LEQAEDWLLR LRALADEPQN SLPDIVIWML
810 820 830 840 850
QGDKRVAYQR VPAHEVLFSR RGTSYCGKNC GKLQTIFLKY PMEGVPRARM
860 870 880 890 900
PVQIRVRLWF GLSVDEKEFN QFAEGKLSVF AETYENQTKL ALVGNWGTTG
910 920 930 940 950
LTYPKFSDIT GRIKLPKDSF RPSAGWAWAG DWFVCPEKTL LHDTDAGHLS
960 970 980 990 1000
FVEEVFENQT RLPGGQWIYM SDNYTDVNGE KVLPKDDIEC PLGWKWEDEE
1010 1020 1030 1040 1050
WSTDLNRAVD EQGWEYSITI PPDRKPRHWV PAEKMYYTHR RRRWVRLRRR
1060 1070 1080 1090 1100
DLSQMEALKR HRQAEAEGEG WEYASLFGWK FHLEYRKTDA FRRRRWRRRM
1110 1120 1130 1140 1150
EPLEKTGPAA VFALEGALGG VVDDRSEDSV SVSTLSFGVN RPTISCIFDY
1160 1170 1180 1190 1200
GNRYHLRCYM YQARDLPAMD KDSFSDPYAV VSFLHQSQKT VVAKNTLNPT
1210 1220 1230 1240 1250
WDQTLIFYEI EIFGEPSSIA EQPPSIVVEL YDHDTYGVDE FMGRCICQPS
1260 1270 1280 1290 1300
LERTPRLAWF PLTRGSQPAG ELLASFELIQ REKPAIHHIP GFEVQDTTGI
1310 1320 1330 1340 1350
LEESEDTDLP YPPPQREANI YMVPQNIKPV LQRTAIEILA WGLRNMKSYQ
1360 1370 1380 1390 1400
LASVSSPSLV VECGGQSVQS CVIKNLRKNP NFDICTLFME VMLPREELYC
1410 1420 1430 1440 1450
PPIVVKVIDN RQFGRRPVVG QCTIRSLEGF LCDPYSEESP SPQGGPDDVS
1460 1470 1480 1490 1500
LLSPGEDVLI DIDDKEPLIP IQFADGLSGL APTNMASSPS SLHKILLEEE
1510 1520 1530 1540 1550
FIDWWSKFFA SIGESEKCGS YLEKDFDTLK VYDTSLENVK AFEGLSDFCN
1560 1570 1580 1590 1600
TFKLYRGKTQ EETEDPSVIG EFKGLFKIYP LPEDPAIPLP PRQFHQLASQ
1610 1620 1630 1640 1650
GPQECLVRVY IIRAFGLQPK DPNGKCDPYI KISIGKKSVS DQDSYIPCTL
1660 1670 1680 1690 1700
EPVFGKMFEL TCTLPLEKDL KVTLYDYDLL SKDEKIGETV IDLENRLLSK
1710 1720 1730 1740 1750
FGARCGLPQT YCVSGPNQWR DQLRPSQLLH LFCQQHRVKA PVYRTDRVVF
1760 1770 1780 1790 1800
QDKEYTVEEI EAGRVPNPHL GPVEERLALH VLQQQGLIPE HVESRPLYSP
1810 1820 1830 1840 1850
LQPDIEQGKL QMWVDLFPKA LGRPGPPFNI TPRRARRFFL RCIIWNTKDV
1860 1870 1880 1890 1900
ILDDLSITGE KMSDIYVKGW MVGFEEHKQK TDVHYRSLGG EGNFNWRFVF
1910 1920 1930 1940 1950
PFDYLPAEQV CTVSKKDAFW RLDKTESKIP ARVVFQIWDN DKFSFDDFLG
1960 1970 1980 1990 2000
SLQLDLNHMP KPAKTAEKCS ADQLEDTFHP ERFVSLFEQK TVKGWWPCVA
2010 2020 2030 2040 2050
EEGEKKILAG KLEMTLEIVT ESEHEERPAG HGRDEPNMNP KLEDPRRPDT
2060 2070 2080 2090 2100
SFLWFTSPYK TMKFILWRRF RCAIIFFLIL FIFLLFLGIF VYSFPNYAAM

KLVKPFS
Length:2,107
Mass (Da):239,314
Last modified:August 21, 2007 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iAE25EADD9780E110
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BC149938 mRNA Translation: AAI49939.1

NCBI Reference Sequences

More...
RefSeqi
NP_001095960.1, NM_001102490.2

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
508157

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
bta:508157

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC149938 mRNA Translation: AAI49939.1
RefSeqiNP_001095960.1, NM_001102490.2

3D structure databases

SMRiA6QQP7
ModBaseiSearch...

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000033077

PTM databases

SwissPalmiA6QQP7

Proteomic databases

PaxDbiA6QQP7
PeptideAtlasiA6QQP7
PRIDEiA6QQP7

Genome annotation databases

GeneIDi508157
KEGGibta:508157

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
8291

Phylogenomic databases

eggNOGiKOG1326, Eukaryota
InParanoidiA6QQP7
OrthoDBi20162at2759

Family and domain databases

CDDicd08373, C2A_Ferlin, 1 hit
cd04011, C2B_Ferlin, 1 hit
cd04018, C2C_Ferlin, 1 hit
cd04017, C2D_Ferlin, 1 hit
cd04037, C2E_Ferlin, 1 hit
cd08374, C2F_Ferlin, 1 hit
Gene3Di2.60.40.150, 6 hits
InterProiView protein in InterPro
IPR000008, C2_dom
IPR035892, C2_domain_sf
IPR037726, C2A_Ferlin
IPR037720, C2B_Ferlin
IPR037722, C2C_Ferlin
IPR037723, C2D_Ferlin
IPR037724, C2E_Ferlin
IPR037725, C2F_Ferlin
IPR029998, Dysferlin
IPR012968, FerIin_dom
IPR037721, Ferlin
IPR012560, Ferlin_A-domain
IPR012561, Ferlin_B-domain
IPR032362, Ferlin_C
IPR006614, Peroxin/Ferlin
PANTHERiPTHR12546, PTHR12546, 1 hit
PTHR12546:SF44, PTHR12546:SF44, 1 hit
PfamiView protein in Pfam
PF00168, C2, 7 hits
PF08165, FerA, 1 hit
PF08150, FerB, 1 hit
PF08151, FerI, 1 hit
PF16165, Ferlin_C, 1 hit
SMARTiView protein in SMART
SM00239, C2, 7 hits
SM00694, DysFC, 2 hits
SM00693, DysFN, 2 hits
SM01200, FerA, 1 hit
SM01201, FerB, 1 hit
SM01202, FerI, 1 hit
PROSITEiView protein in PROSITE
PS50004, C2, 7 hits

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiDYSF_BOVIN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A6QQP7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 16, 2008
Last sequence update: August 21, 2007
Last modified: June 2, 2021
This is version 74 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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