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Protein

Kinesin-like protein

Gene

KIF2C

Organism
Bos taurus (Bovine)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi346 – 353ATPPROSITE-ProRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMotor proteinPROSITE-ProRule annotation
LigandATP-bindingPROSITE-ProRule annotationSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-BTA-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
R-BTA-2132295 MHC class II antigen presentation
R-BTA-2467813 Separation of Sister Chromatids
R-BTA-2500257 Resolution of Sister Chromatid Cohesion
R-BTA-5663220 RHO GTPases Activate Formins
R-BTA-6811434 COPI-dependent Golgi-to-ER retrograde traffic
R-BTA-68877 Mitotic Prometaphase
R-BTA-983189 Kinesins

Names & Taxonomyi

Protein namesi
Recommended name:
Kinesin-like proteinUniRule annotation
Gene namesi
Name:KIF2CImported
OrganismiBos taurus (Bovine)Imported
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 3

Organism-specific databases

VGNCiVGNC:30601 KIF2C

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

MicrotubuleUniRule annotation

Expressioni

Gene expression databases

BgeeiENSBTAG00000015280

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000020322

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini256 – 586Kinesin motorInterPro annotationAdd BLAST331

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili189 – 221Sequence analysisAdd BLAST33
Coiled coili632 – 656Sequence analysisAdd BLAST25

Sequence similaritiesi

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.PROSITE-ProRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0246 Eukaryota
COG5059 LUCA
GeneTreeiENSGT00920000148953
HOGENOMiHOG000231329
HOVERGENiHBG003875
KOiK10393
OMAiFAFDETA
OrthoDBiEOG091G06V3
TreeFamiTF105222

Family and domain databases

Gene3Di3.40.850.10, 1 hit
InterProiView protein in InterPro
IPR027640 Kinesin-like_fam
IPR019821 Kinesin_motor_CS
IPR001752 Kinesin_motor_dom
IPR036961 Kinesin_motor_dom_sf
IPR027417 P-loop_NTPase
PANTHERiPTHR24115 PTHR24115, 1 hit
PfamiView protein in Pfam
PF00225 Kinesin, 1 hit
PRINTSiPR00380 KINESINHEAVY
SMARTiView protein in SMART
SM00129 KISc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00411 KINESIN_MOTOR_1, 1 hit
PS50067 KINESIN_MOTOR_2, 1 hit

Sequencei

Sequence statusi: Complete.

A6QPE8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDSSLQARLF PGLTIKIQRS NGIIHSASIS TVNLEKSCVS VEWKEGGDTK
60 70 80 90 100
GKEVDFDDVA AINPELLQLL PLHLKDNLPL QENVTVQKQK RRSVSSRIPA
110 120 130 140 150
PKEGLRGRST RMSAVSEVRI TTQENDMEVE LPASANSRKQ FSVAAGPSRP
160 170 180 190 200
SCPAVSEIPL TMVSKEVEEQ VHSVRDSSSA NSVKSVRRKS CIVKEMEKMK
210 220 230 240 250
NKREEKRAQN SEMRIKRAQE YDNSFPNWEF ARMIKEFRAT LECHPLTAAD
260 270 280 290 300
PIEEHRICVC VRKRPLNKQE LAKKEIDVIS VPSKCVLLVH EPKLKVDLTK
310 320 330 340 350
YLENQAFCFD FAFDETTSNE VVYRFTARPL VQTIFEGGKA TCFAYGQTGS
360 370 380 390 400
GKTHTMGGDL YGKAQNASKG IYAMASRDVF LLKNQPRYRK LDLEVYVTFF
410 420 430 440 450
EIYNGKLFDL LNKKAKLRVL EDGKQQVQVV GLQERLVSCA DDVIKMIDIG
460 470 480 490 500
SACRTSGQTF ANSNSSRSHA CFQILLRTKG RVHGKFSLVD LAGNERGADT
510 520 530 540 550
SSADRQTRME GAEINKSLLA LKECIRALGQ NKAHTPFRES KLTQVLRDSF
560 570 580 590 600
IGENSRTCMI AMISPGISSC EYTLNTLRYA DRVKELSPHS GPSGEQPMQM
610 620 630 640 650
ETEEMEAGSN GALSAGNFSK EEDELSSQMS SFNEAMTQIR ELEERAMEEL
660 670 680 690 700
KEIIQQGPGW LELSEMAEQP DYDLETFVNK AECALAQQAK HFSALRDVIK
710 720
ALRLAMQLEE QASKQISSKK RPQ
Length:723
Mass (Da):81,024
Last modified:August 21, 2007 - v1
Checksum:iFF14A5F1741CB996
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DAAA02009019 Genomic DNA No translation available.
BC149279 mRNA Translation: AAI49280.1
RefSeqiNP_001094617.1, NM_001101147.1
UniGeneiBt.15730

Genome annotation databases

EnsembliENSBTAT00000020322; ENSBTAP00000020322; ENSBTAG00000015280
GeneIDi533161
KEGGibta:533161

Similar proteinsi

Entry informationi

Entry nameiA6QPE8_BOVIN
AccessioniPrimary (citable) accession number: A6QPE8
Secondary accession number(s): F1MU44
Entry historyiIntegrated into UniProtKB/TrEMBL: August 21, 2007
Last sequence update: August 21, 2007
Last modified: June 20, 2018
This is version 100 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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