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Protein
Submitted name:

UBE4B protein

Gene

UBE4B

Organism
Bos taurus (Bovine)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • ATP binding Source: Ensembl
  • enzyme binding Source: Ensembl
  • ubiquitin-ubiquitin ligase activity Source: GO_Central

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
UBE4B proteinImported
Submitted name:
Ubiquitination factor E4BImported
Gene namesi
Name:UBE4BImported
OrganismiBos taurus (Bovine)Imported
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 16

Organism-specific databases

VGNCiVGNC:36604 UBE4B

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSBTAG00000010401 Expressed in 9 organ(s), highest expression level in heart

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000013729

Structurei

3D structure databases

SMRiA6QNS2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1287 – 1360U-boxInterPro annotationAdd BLAST74

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili843 – 863Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG2042 Eukaryota
COG5113 LUCA
GeneTreeiENSGT00390000009300
HOGENOMiHOG000294109
HOVERGENiHBG058129
KOiK10597
OMAiAMWNHEL
OrthoDBiEOG091G02B4
TreeFamiTF300802

Family and domain databases

Gene3Di3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR019474 Ub_conjug_fac_E4_core
IPR003613 Ubox_domain
IPR013083 Znf_RING/FYVE/PHD
PfamiView protein in Pfam
PF04564 U-box, 1 hit
PF10408 Ufd2P_core, 1 hit
SMARTiView protein in SMART
SM00504 Ubox, 1 hit
PROSITEiView protein in PROSITE
PS51698 U_BOX, 1 hit

Sequencei

Sequence statusi: Complete.

A6QNS2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEELSADEIR RRRLARLAGG QTSQPTTPLT SPQRENPPGP PIAASAPGPS
60 70 80 90 100
QSLGLNVHNM TPATSPIGAS GVAHRSQSSE GVSSLSSSPS NSLETQSQSL
110 120 130 140 150
SRSQSMDIDG VSCEKSMSQV DVDSGIENME VDENDRREKR SLSDKEPSSG
160 170 180 190 200
SEVSEEQALQ LVCKIFRVSW KDRDRDVIFL SSLSAQFKQN PKEVFSDFKD
210 220 230 240 250
LIGQILMEVL MMSTQTRDEN PFASLTATSQ PIAATARSPD RNLMLTTGSN
260 270 280 290 300
PGTSPMFCNL GSFGASSLSS LYETSPAPNT SVWSSVPMMS PPLASPSRAA
310 320 330 340 350
SQAAVPPASS LCPPGPAGTP AGSQPSSPRY RPYTVTHPSG STSTPASRSS
360 370 380 390 400
GTSILSSSPG LSAPASSPQA VPTSSSRQRP PGTGPPLLSA SPGGSAPSRR
410 420 430 440 450
PSSLRNSPSM YDSPFSFLFL ALSGDSSDED EEDDDDGDDG DDEGGGGGDE
460 470 480 490 500
FSCVQFGSSL GASGGASTWD SYSDHFTIET CKETDMLNYL IECFDRVGIE
510 520 530 540 550
EKKAPKMCSQ PAVSQLLSNI RSQCISHTAL VLQGSLTQPR SLQQPSFLVP
560 570 580 590 600
YMLCRNLPYG FIQELVRTTH QDEEVFKQIF IPILQGLALA AKECSLDSDY
610 620 630 640 650
FKYPLMALGE LCETKFGKTH PVCNLVASLP LWLPKSLSPG SGRELQRLSY
660 670 680 690 700
LGAFFSFSVF AEDDAKVVEK YFSGPAITLE NTRVVSQSLQ HYLELGRQEL
710 720 730 740 750
FKILHSILLN GETREAALSY MAAVVNANMK KAQMQTDDRL VSTDGFMLNF
760 770 780 790 800
LWVLQQLSTK IKLETVDPTY IFHPRCRITL PNDETRVNAT MEDVNDWLAE
810 820 830 840 850
LYGDQPPFSE PKFPTECFFL TLHAHHLSIL PSCRRYIRRL RAIRELNRTV
860 870 880 890 900
EDLKNNESQW KDSPLATRHR EMLKRCKTQL KKLVRCKACA DAGLLDESFL
910 920 930 940 950
RRCLNFYGLL IQLLLRLLDP AYPDVTLPLN SDVPKVFAAL PEFYVEDVAE
960 970 980 990 1000
FLFFIVQYSP QVLYEPCTQD IVMFLVVMLC NQNYIRNPYL VAKLVEVMFM
1010 1020 1030 1040 1050
TNPAVQPRTQ KFFEMIENHP LSTKLLVPSL MKFYTDVEHT GATSEFYDKF
1060 1070 1080 1090 1100
TIRYHISTIF KSLWQNIAHH GTFMEEFNSG KQFVRYINML INDTTFLLDE
1110 1120 1130 1140 1150
SLESLKRIHE VQEEMKNKEQ WDQLPRDQQQ ARQSQLAQDE RVSRSYLALA
1160 1170 1180 1190 1200
TETVDMFHIL TKQVQKPFLR PELGPRLAAM LNFNLQQLCG PKCRDLKVEN
1210 1220 1230 1240 1250
PEKYGFEPKK LLDQLTDIYL QLDCARFAKA IADDQRSYSK ELFEEVISKM
1260 1270 1280 1290 1300
RKAGIKSTIA IEKFKLLAEK VEEIVAKNAR AEIDYSDAPD EFRDPLMDTL
1310 1320 1330 1340 1350
MTDPVRLPSG TIMDRSIILR HLLNSPTDPF NRQTLTESML EPVPELKEQI
1360
HAWMREKQNS DH
Length:1,362
Mass (Da):152,079
Last modified:August 21, 2007 - v1
Checksum:i1C24776B6921E6B0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DAAA02042992 Genomic DNA No translation available.
BC148970 mRNA Translation: AAI48971.1
RefSeqiNP_001095974.1, NM_001102504.1
UniGeneiBt.17976

Genome annotation databases

EnsembliENSBTAT00000013729; ENSBTAP00000013729; ENSBTAG00000010401
GeneIDi520833
KEGGibta:520833

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DAAA02042992 Genomic DNA No translation available.
BC148970 mRNA Translation: AAI48971.1
RefSeqiNP_001095974.1, NM_001102504.1
UniGeneiBt.17976

3D structure databases

SMRiA6QNS2
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000013729

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSBTAT00000013729; ENSBTAP00000013729; ENSBTAG00000010401
GeneIDi520833
KEGGibta:520833

Organism-specific databases

CTDi10277
VGNCiVGNC:36604 UBE4B

Phylogenomic databases

eggNOGiKOG2042 Eukaryota
COG5113 LUCA
GeneTreeiENSGT00390000009300
HOGENOMiHOG000294109
HOVERGENiHBG058129
KOiK10597
OMAiAMWNHEL
OrthoDBiEOG091G02B4
TreeFamiTF300802

Gene expression databases

BgeeiENSBTAG00000010401 Expressed in 9 organ(s), highest expression level in heart

Family and domain databases

Gene3Di3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR019474 Ub_conjug_fac_E4_core
IPR003613 Ubox_domain
IPR013083 Znf_RING/FYVE/PHD
PfamiView protein in Pfam
PF04564 U-box, 1 hit
PF10408 Ufd2P_core, 1 hit
SMARTiView protein in SMART
SM00504 Ubox, 1 hit
PROSITEiView protein in PROSITE
PS51698 U_BOX, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA6QNS2_BOVIN
AccessioniPrimary (citable) accession number: A6QNS2
Entry historyiIntegrated into UniProtKB/TrEMBL: August 21, 2007
Last sequence update: August 21, 2007
Last modified: November 7, 2018
This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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