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Entry version 88 (08 May 2019)
Sequence version 3 (10 Aug 2010)
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Protein

Ankyrin repeat domain-containing protein 36A

Gene

ANKRD36

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Ankyrin repeat domain-containing protein 36A
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ANKRD36
Synonyms:ANKRD36A, KIAA1641
ORF Names:UNQ2430/PRO499
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:24079 ANKRD36

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_A6QL64

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
375248

Open Targets

More...
OpenTargetsi
ENSG00000135976

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ANKRD36

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003345441 – 1941Ankyrin repeat domain-containing protein 36AAdd BLAST1941

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
A6QL64

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
A6QL64

MaxQB - The MaxQuant DataBase

More...
MaxQBi
A6QL64

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
A6QL64

PRoteomics IDEntifications database

More...
PRIDEi
A6QL64

ProteomicsDB human proteome resource

More...
ProteomicsDBi
1746
1747 [A6QL64-3]
1748 [A6QL64-4]
1749 [A6QL64-5]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
A6QL64

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
A6QL64

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000135976 Expressed in 92 organ(s), highest expression level in corpus callosum

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
A6QL64 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
A6QL64 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA051757
HPA057661

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
131962, 4 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000391950

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
A6QL64

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati31 – 60ANK 1Add BLAST30
Repeati64 – 93ANK 2Add BLAST30
Repeati97 – 126ANK 3Add BLAST30
Repeati130 – 159ANK 4Add BLAST30
Repeati163 – 192ANK 5Add BLAST30
Repeati196 – 225ANK 6Add BLAST30

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili1319 – 1350Sequence analysisAdd BLAST32
Coiled coili1409 – 1494Sequence analysisAdd BLAST86
Coiled coili1525 – 1643Sequence analysisAdd BLAST119
Coiled coili1707 – 1932Sequence analysisAdd BLAST226

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the ANKRD36 family.Curated

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

ANK repeat, Coiled coil, Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0504 Eukaryota
COG0666 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000163264

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000185155

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
A6QL64

Identification of Orthologs from Complete Genome Data

More...
OMAi
SANEQIN

Database of Orthologous Groups

More...
OrthoDBi
110145at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
A6QL64

TreeFam database of animal gene trees

More...
TreeFami
TF333496

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00204 ANK, 2 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.40.20, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR039497 CC144C-like_CC_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12796 Ank_2, 2 hits
PF14915 CCDC144C, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00248 ANK, 6 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48403 SSF48403, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 5 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 4 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: A6QL64-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MEDGKRERWP TLMERLCSDG FAFPQYPIKP YHLKRIHRAV LHGNLEKLKY
60 70 80 90 100
LLLTYYDANK RDRKERTALH LACATGQPEM VHLLVSRRCE LNLCDREDRT
110 120 130 140 150
PLIKAVQLRQ EACATLLLQN GANPNITDFF GRTALHYAVY NEDTSMIEKL
160 170 180 190 200
LSHGTNIEEC SKCEYQPLLF AVSRRKVKMV EFLLKKKANV NAIDYLGRSA
210 220 230 240 250
LIHAVTLGEK DIVILLLQHN IDVLSRDAFR KIAGDYAIEA KNRVIFDLIY
260 270 280 290 300
EYERKRYEDL PINSNPVSSQ KQPALKATSG KEDSISNIAT EIKDGQKSGT
310 320 330 340 350
VSSQKQPALK DTSDKDDSVS NTATEIKDEQ KSGTVLPAVE QCLNRSLYRP
360 370 380 390 400
DAVAQPVTEN EFSLESEIIS KLYIPKRKII SPRSIKDVLP PVEEAVDRCL
410 420 430 440 450
YLLDRFAQPV TKDKFALESE NISEPYFTNR RTISQQSAEN LDAACGIDKT
460 470 480 490 500
ENGNMFEDQN VDKEGKALPA TGQKANVSPE QPPLFTHTVK DRDHISTRFL
510 520 530 540 550
GGMDSLTSSE ESSERPPLST LTLKEADPSS KAAMRRKDSP PPGKVSSQKQ
560 570 580 590 600
PAEKATSDDK DSVSNIATEI KEGPISGTVS SQKQPAEKAT SDEKDSVSNI
610 620 630 640 650
ATEIKKGQQS GTVSPQKQSA WKVIFKKKVS LLNIATRIMG GGKSGTVSSQ
660 670 680 690 700
KQPASKATSD KTDSALNIAT EIKDGLQCGT VSSQKQPALK ATTDEEDSVS
710 720 730 740 750
NIATEIKDGE KSGTVSSQKQ PALKATTDEE DSVSNIATEI KDGEKSGTVS
760 770 780 790 800
SQKQPALKAT TDEKDSVSNI ATEIKDGEKS GTVSSQKPPA LTATSDEEGS
810 820 830 840 850
VLSIARENKD GEKSRTVSSR KKPALKATSD EKDSFSNITR GKKDGEISRK
860 870 880 890 900
VSSQKPPTLK GTSDEEDSVL GIARENKDGE KSRTVSSEKP PGLKASSAEK
910 920 930 940 950
DSVLNIARGK KDGEKTKRVS SRKKPSLEAT SDEKDSFSNI TREKKDGEIS
960 970 980 990 1000
RKVSSQKPPA LKGTSDEEDS VLGIARENKD GEKSRTVSSE KPPGLKATSD
1010 1020 1030 1040 1050
EKDSVLNIAR GKKDGEKTRT VSSQKPPTLK ATSDEEDSVL SIARENKDGE
1060 1070 1080 1090 1100
KSRTVSSEKP SGLKATSAEK DSVLNIARGK KYGEKTKRVS SRKKPALKAT
1110 1120 1130 1140 1150
SDEKDSVLYI AREKKDGEKS RTVSSPKQPA LKAICDKEDS VPNMATEKKD
1160 1170 1180 1190 1200
EQISGTVSCQ KQPALKATSD KKDSVSNIPT EIKDGQQSGT VSSQKQPAWK
1210 1220 1230 1240 1250
ATSVKKDSVS NIATEIKDGQ IRGTGILEYT FNVMFDQIEE KFTSLNKSAG
1260 1270 1280 1290 1300
VSPQKQSAQK VIFKKKVSLL NIATRITGGW KSGTEYPENL PTLKATIENK
1310 1320 1330 1340 1350
NSVLNTATKM KDVQTSTPAE QDLEMASEGE QKRLEEYENN QPQVKNQIHS
1360 1370 1380 1390 1400
RDDLDDIIQS SQTVSEDGDS LCCNCKNVIL LIDQHEMKCK DCVHLLKIKN
1410 1420 1430 1440 1450
TFCLWKRLIK LKDNHCEQLR VKIRKLKNKA SVLQKRISEK EEIKSQLKHE
1460 1470 1480 1490 1500
ILELEKELCS LRFAIQQEKK KRRNVEEVHQ KVREKLRITE EQYRIEADVT
1510 1520 1530 1540 1550
KPIKPALKSA EVELKTGGNN SNQVSETDEK EDLLHENRLM QDEIARLRLE
1560 1570 1580 1590 1600
KDTIKNQNLE KKYLKDFEIV KRKHEDLQKA LKRNGETLAK TIACYSGQLA
1610 1620 1630 1640 1650
ALTDENTTLR SKLEKQRESR QRLETEMQSY HCRLNAARCD HDQSHSSKRD
1660 1670 1680 1690 1700
QELAFQGTVD KCRHLQENLN SHVLILSLQL SKAESKSRVL KTELHYTGEA
1710 1720 1730 1740 1750
LKEKALVFEH VQSELKQKQS QMKDIEKMYK SGYNTMEKCI EKQERFCQLK
1760 1770 1780 1790 1800
KQNMLLQQQL DDARNKADNQ EKAILNIQAR CDARVQNLQA ECRKHRLLLE
1810 1820 1830 1840 1850
EDNKMLVNEL NHSKEKECQY EKEKAEREVA VRQLQQKRDD VLNKGSATKA
1860 1870 1880 1890 1900
LLDASSRHCT YLENGMQDSR KKLDQMRSQF QEIQDQLTAT IRCTKEMEGD
1910 1920 1930 1940
TQKLEVEHVM MRKIIKKQDD QIERLEKILQ HSSLMLQVFE S
Length:1,941
Mass (Da):217,465
Last modified:August 10, 2010 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iDF492CB9ED173FE6
GO
Isoform 2 (identifier: A6QL64-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-1149: Missing.
     1150-1159: DEQISGTVSC → MYPFCFSVSS
     1225-1250: Missing.
     1319-1319: Missing.
     1880-1892: FQEIQDQLTATIR → VCMQLCTPTTVNL
     1893-1941: Missing.

Show »
Length:716
Mass (Da):82,759
Checksum:iE5BCF1176718C9EA
GO
Isoform 3 (identifier: A6QL64-4) [UniParc] [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     163-163: C → V
     164-1941: Missing.

Show »
Length:163
Mass (Da):18,915
Checksum:i0609BBDE2633E175
GO
Isoform 4 (identifier: A6QL64-5) [UniParc] [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     164-170: EYQPLLF → LLRNNQP
     171-1941: Missing.

Show »
Length:170
Mass (Da):19,755
Checksum:i3ABC2357DB54D12A
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A087X037A0A087X037_HUMAN
Ankyrin repeat domain-containing pr...
ANKRD36
309Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1W2PS33A0A1W2PS33_HUMAN
Ankyrin repeat domain-containing pr...
ANKRD36
308Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAQ88934 differs from that shown. Reason: Frameshift at position 5.Curated
The sequence AAQ88934 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence BAB13467 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0396561 – 1149Missing in isoform 2. 3 PublicationsAdd BLAST1149
Alternative sequenceiVSP_039657163C → V in isoform 3. 2 Publications1
Alternative sequenceiVSP_039658164 – 1941Missing in isoform 3. 2 PublicationsAdd BLAST1778
Alternative sequenceiVSP_039659164 – 170EYQPLLF → LLRNNQP in isoform 4. 1 Publication7
Alternative sequenceiVSP_039660171 – 1941Missing in isoform 4. 1 PublicationAdd BLAST1771
Alternative sequenceiVSP_0396611150 – 1159DEQISGTVSC → MYPFCFSVSS in isoform 2. 3 Publications10
Alternative sequenceiVSP_0396621225 – 1250Missing in isoform 2. 3 PublicationsAdd BLAST26
Alternative sequenceiVSP_0396631319Missing in isoform 2. 3 Publications1
Alternative sequenceiVSP_0396641880 – 1892FQEIQ…TATIR → VCMQLCTPTTVNL in isoform 2. 3 PublicationsAdd BLAST13
Alternative sequenceiVSP_0396651893 – 1941Missing in isoform 2. 3 PublicationsAdd BLAST49

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB046861 mRNA Translation: BAB13467.1 Different initiation.
AY358571 mRNA Translation: AAQ88934.1 Sequence problems.
AK304740 mRNA Translation: BAG65500.1
AK316541 mRNA Translation: BAH14912.1
AC018892 Genomic DNA Translation: AAY14642.1
BC046186 mRNA Translation: AAH46186.1
BC146835 mRNA Translation: AAI46836.1
AF543495 mRNA Translation: AAN40505.1

NCBI Reference Sequences

More...
RefSeqi
NP_001157787.1, NM_001164315.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000420699; ENSP00000391950; ENSG00000135976 [A6QL64-1]

UCSC genome browser

More...
UCSCi
uc010yva.3 human [A6QL64-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB046861 mRNA Translation: BAB13467.1 Different initiation.
AY358571 mRNA Translation: AAQ88934.1 Sequence problems.
AK304740 mRNA Translation: BAG65500.1
AK316541 mRNA Translation: BAH14912.1
AC018892 Genomic DNA Translation: AAY14642.1
BC046186 mRNA Translation: AAH46186.1
BC146835 mRNA Translation: AAI46836.1
AF543495 mRNA Translation: AAN40505.1
RefSeqiNP_001157787.1, NM_001164315.1

3D structure databases

SMRiA6QL64
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi131962, 4 interactors
STRINGi9606.ENSP00000391950

PTM databases

iPTMnetiA6QL64
PhosphoSitePlusiA6QL64

Polymorphism and mutation databases

BioMutaiANKRD36

Proteomic databases

EPDiA6QL64
jPOSTiA6QL64
MaxQBiA6QL64
PaxDbiA6QL64
PRIDEiA6QL64
ProteomicsDBi1746
1747 [A6QL64-3]
1748 [A6QL64-4]
1749 [A6QL64-5]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
375248
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000420699; ENSP00000391950; ENSG00000135976 [A6QL64-1]
UCSCiuc010yva.3 human [A6QL64-1]

Organism-specific databases

DisGeNETi375248

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ANKRD36

H-Invitational Database, human transcriptome db

More...
H-InvDBi
HIX0002250
HIX0161601
HGNCiHGNC:24079 ANKRD36
HPAiHPA051757
HPA057661
neXtProtiNX_A6QL64
OpenTargetsiENSG00000135976

Human Unidentified Gene-Encoded large proteins database

More...
HUGEi
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GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiKOG0504 Eukaryota
COG0666 LUCA
GeneTreeiENSGT00940000163264
HOGENOMiHOG000185155
InParanoidiA6QL64
OMAiSANEQIN
OrthoDBi110145at2759
PhylomeDBiA6QL64
TreeFamiTF333496

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
ANKRD36 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
375248

Protein Ontology

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PROi
PR:A6QL64

Gene expression databases

BgeeiENSG00000135976 Expressed in 92 organ(s), highest expression level in corpus callosum
ExpressionAtlasiA6QL64 baseline and differential
GenevisibleiA6QL64 HS

Family and domain databases

CDDicd00204 ANK, 2 hits
Gene3Di1.25.40.20, 1 hit
InterProiView protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR039497 CC144C-like_CC_dom
PfamiView protein in Pfam
PF12796 Ank_2, 2 hits
PF14915 CCDC144C, 1 hit
SMARTiView protein in SMART
SM00248 ANK, 6 hits
SUPFAMiSSF48403 SSF48403, 1 hit
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 5 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiAN36A_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A6QL64
Secondary accession number(s): B4E3I8
, Q6UX02, Q86X62, Q9HCD1
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: August 10, 2010
Last modified: May 8, 2019
This is version 88 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM
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