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UniProtKB - A6P7M9 (A6P7M9_9ACTN)
Protein
Submitted name:
Sphingomyelinase C
Gene
smc
Organism
Streptomyces griseocarneus
Status
Functioni
GO - Molecular functioni
- sphingomyelin phosphodiesterase activity Source: UniProtKB-EC
Keywordsi
Molecular function | HydrolaseImported |
Enzyme and pathway databases
BRENDAi | 3.1.4.12, 6027 |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:smcImported |
Organismi | Streptomyces griseocarneusImported |
Taxonomic identifieri | 51201 [NCBI] |
Taxonomic lineagei | Bacteria › Actinobacteria › Streptomycetales › Streptomycetaceae › Streptomyces |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 42 | Sequence analysisAdd BLAST | 42 | |
ChainiPRO_5002698087 | 43 – 339 | Sequence analysisAdd BLAST | 297 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Disulfide bondi | 163 ↔ 199 | Combined sources |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 75 – 301 | Endo/exonuclease/phosphataseInterPro annotationAdd BLAST | 227 |
Keywords - Domaini
SignalSequence analysisFamily and domain databases
CDDi | cd09078, nSMase, 1 hit |
Gene3Di | 3.60.10.10, 1 hit |
InterProi | View protein in InterPro IPR036691, Endo/exonu/phosph_ase_sf IPR005135, Endo/exonuclease/phosphatase IPR017766, Sphingomyelinase/PLipase_C |
Pfami | View protein in Pfam PF03372, Exo_endo_phos, 1 hit |
SUPFAMi | SSF56219, SSF56219, 1 hit |
TIGRFAMsi | TIGR03395, sphingomy, 1 hit |
i Sequence
Sequence statusi: Complete.
A6P7M9-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAQARSPTPT PGAAVPFTQR TATAALFTAA ALTAALPQTA MAAPAAATPS
60 70 80 90 100
LKVLTYNTFL MSTGLYPNWG QEHRAREIAA AGFFQGNDVV VLQEAFDNAA
110 120 130 140 150
ADGLKAAAAD RYPYQTPVVG RSRDGWDATG GKYSATTPED GGVTVLSKWP
160 170 180 190 200
IVRKEQVIFN DACGADWWSN KGFAYVVLNV GGTRVHVVGT HAQSTDSGCA
210 220 230 240 250
AGEAAADRSR QFRQIDAFLD AKNIPADEQV MLAGDLNVDS HSAEYASMLA
260 270 280 290 300
DGDLAPADSR AGHPYSFDTK ENSIAAYRYP TDPREDLDYV LHRNGHARPA
310 320 330
GWRNTVVQET SAPWTVSSWG KRYTYTDLSG HYPVIAGAN
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB332112 Genomic DNA Translation: BAF73613.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB332112 Genomic DNA Translation: BAF73613.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
7CNE | X-ray | 2.00 | A | 43-339 | [»] | |
SMRi | A6P7M9 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Enzyme and pathway databases
BRENDAi | 3.1.4.12, 6027 |
Family and domain databases
CDDi | cd09078, nSMase, 1 hit |
Gene3Di | 3.60.10.10, 1 hit |
InterProi | View protein in InterPro IPR036691, Endo/exonu/phosph_ase_sf IPR005135, Endo/exonuclease/phosphatase IPR017766, Sphingomyelinase/PLipase_C |
Pfami | View protein in Pfam PF03372, Exo_endo_phos, 1 hit |
SUPFAMi | SSF56219, SSF56219, 1 hit |
TIGRFAMsi | TIGR03395, sphingomy, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | A6P7M9_9ACTN | |
Accessioni | A6P7M9Primary (citable) accession number: A6P7M9 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | August 21, 2007 |
Last sequence update: | August 21, 2007 | |
Last modified: | April 7, 2021 | |
This is version 49 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |