UniProtKB - A6NP61 (ZAR1L_HUMAN)
Protein
ZAR1-like protein
Gene
ZAR1L
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- mRNA binding involved in posttranscriptional gene silencing Source: GO_Central
GO - Biological processi
- translation Source: GO_Central
Enzyme and pathway databases
PathwayCommonsi | A6NP61 |
Names & Taxonomyi
Protein namesi | Recommended name: ZAR1-like protein |
Gene namesi | Name:ZAR1L |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:37116, ZAR1L |
neXtProti | NX_A6NP61 |
VEuPathDBi | HostDB:ENSG00000189167.11 |
Subcellular locationi
Other locations
- cytoplasm Source: GO_Central
Pathology & Biotechi
Organism-specific databases
DisGeNETi | 646799 |
OpenTargetsi | ENSG00000189167 |
PharmGKBi | PA165505636 |
Miscellaneous databases
Pharosi | A6NP61, Tdark |
Genetic variation databases
BioMutai | ZAR1L |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000332227 | 1 – 321 | ZAR1-like proteinAdd BLAST | 321 |
Proteomic databases
PaxDbi | A6NP61 |
PeptideAtlasi | A6NP61 |
PRIDEi | A6NP61 |
ProteomicsDBi | 1661 |
PTM databases
iPTMneti | A6NP61 |
PhosphoSitePlusi | A6NP61 |
Expressioni
Gene expression databases
Bgeei | ENSG00000189167, Expressed in thoracic aorta and 18 other tissues |
Organism-specific databases
HPAi | ENSG00000189167, Tissue enhanced (brain, gallbladder, testis) |
Interactioni
Protein-protein interaction databases
BioGRIDi | 571620, 17 interactors |
STRINGi | 9606.ENSP00000437289 |
Miscellaneous databases
RNActi | A6NP61, protein |
Family & Domainsi
Sequence similaritiesi
Belongs to the ZAR1 family.Curated
Phylogenomic databases
eggNOGi | ENOG502QWC9, Eukaryota |
GeneTreei | ENSGT00390000012305 |
HOGENOMi | CLU_053350_1_0_1 |
InParanoidi | A6NP61 |
OMAi | GCSQTCC |
OrthoDBi | 822936at2759 |
PhylomeDBi | A6NP61 |
TreeFami | TF331383 |
Family and domain databases
InterProi | View protein in InterPro IPR026775, Zar1 IPR027377, Znf-3CxxC |
PANTHERi | PTHR31054, PTHR31054, 1 hit |
Pfami | View protein in Pfam PF13695, zf-3CxxC, 1 hit |
SMARTi | View protein in SMART SM01328, zf-3CxxC, 1 hit |
i Sequence
Sequence statusi: Complete.
A6NP61-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MERFVRVPYG LYQGYGSTVP LGQPGLSGHK QPDWRQNMGP PTFLARPGLL
60 70 80 90 100
VPANAPDYCI DPYKRAQLKA ILSQMNPSLS PRLCKPNTKE VGVQVSPRVD
110 120 130 140 150
KAVQCSLGPR TLSSCSPWDG RDPQEPLPAC GVTSPATGRR GLIRLRRDGD
160 170 180 190 200
EAESKALPGP AEASQPQPPS RRSGADRQEE PGQLEESGEK DAPCPQETKS
210 220 230 240 250
KQVPGDAASE PLRRPNFQFL EPKYGYFHCK DCKTRWESAY VWCISGTNKV
260 270 280 290 300
YFKQLCCKCQ KSFNPYRVEA IQCQTCSKSH CSCPQKKRHI DLRRPHRQEL
310 320
CGRCKDKRFS CGNIYSFKYV M
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL445212 Genomic DNA No translation available. BC146956 mRNA Translation: AAI46957.1 BC146965 mRNA Translation: AAI46966.1 |
CCDSi | CCDS45023.1 |
RefSeqi | NP_001130043.1, NM_001136571.1 |
Genome annotation databases
Ensembli | ENST00000345108; ENSP00000344616; ENSG00000189167 ENST00000533490; ENSP00000437289; ENSG00000189167 |
GeneIDi | 646799 |
KEGGi | hsa:646799 |
UCSCi | uc010abc.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL445212 Genomic DNA No translation available. BC146956 mRNA Translation: AAI46957.1 BC146965 mRNA Translation: AAI46966.1 |
CCDSi | CCDS45023.1 |
RefSeqi | NP_001130043.1, NM_001136571.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 571620, 17 interactors |
STRINGi | 9606.ENSP00000437289 |
PTM databases
iPTMneti | A6NP61 |
PhosphoSitePlusi | A6NP61 |
Genetic variation databases
BioMutai | ZAR1L |
Proteomic databases
PaxDbi | A6NP61 |
PeptideAtlasi | A6NP61 |
PRIDEi | A6NP61 |
ProteomicsDBi | 1661 |
Protocols and materials databases
Antibodypediai | 49134, 41 antibodies |
Genome annotation databases
Ensembli | ENST00000345108; ENSP00000344616; ENSG00000189167 ENST00000533490; ENSP00000437289; ENSG00000189167 |
GeneIDi | 646799 |
KEGGi | hsa:646799 |
UCSCi | uc010abc.1, human |
Organism-specific databases
CTDi | 646799 |
DisGeNETi | 646799 |
GeneCardsi | ZAR1L |
HGNCi | HGNC:37116, ZAR1L |
HPAi | ENSG00000189167, Tissue enhanced (brain, gallbladder, testis) |
neXtProti | NX_A6NP61 |
OpenTargetsi | ENSG00000189167 |
PharmGKBi | PA165505636 |
VEuPathDBi | HostDB:ENSG00000189167.11 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | ENOG502QWC9, Eukaryota |
GeneTreei | ENSGT00390000012305 |
HOGENOMi | CLU_053350_1_0_1 |
InParanoidi | A6NP61 |
OMAi | GCSQTCC |
OrthoDBi | 822936at2759 |
PhylomeDBi | A6NP61 |
TreeFami | TF331383 |
Enzyme and pathway databases
PathwayCommonsi | A6NP61 |
Miscellaneous databases
BioGRID-ORCSi | 646799, 7 hits in 867 CRISPR screens |
ChiTaRSi | ZAR1L, human |
GenomeRNAii | 646799 |
Pharosi | A6NP61, Tdark |
PROi | PR:A6NP61 |
RNActi | A6NP61, protein |
Gene expression databases
Bgeei | ENSG00000189167, Expressed in thoracic aorta and 18 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR026775, Zar1 IPR027377, Znf-3CxxC |
PANTHERi | PTHR31054, PTHR31054, 1 hit |
Pfami | View protein in Pfam PF13695, zf-3CxxC, 1 hit |
SMARTi | View protein in SMART SM01328, zf-3CxxC, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | ZAR1L_HUMAN | |
Accessioni | A6NP61Primary (citable) accession number: A6NP61 Secondary accession number(s): B2RV03, B7ZBU2 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 29, 2008 |
Last sequence update: | January 15, 2008 | |
Last modified: | February 10, 2021 | |
This is version 95 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Human chromosome 13
Human chromosome 13: entries, gene names and cross-references to MIM - SIMILARITY comments
Index of protein domains and families