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Protein

Uncharacterized protein C16orf96

Gene

C16orf96

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Uncharacterized protein C16orf96Curated
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:C16orf96Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 16

Organism-specific databases

Eukaryotic Pathogen Database Resources

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EuPathDBi
HostDB:ENSG00000205832.7

Human Gene Nomenclature Database

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HGNCi
HGNC:40031 C16orf96

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_A6NNT2

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

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OpenTargetsi
ENSG00000205832

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
C16orf96

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003456281 – 1141Uncharacterized protein C16orf96Add BLAST1141

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

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PaxDbi
A6NNT2

PRoteomics IDEntifications database

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PRIDEi
A6NNT2

ProteomicsDB human proteome resource

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ProteomicsDBi
1635

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
A6NNT2

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

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PhosphoSitePlusi
A6NNT2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000205832 Expressed in 35 organ(s), highest expression level in testis

Organism-specific databases

Human Protein Atlas

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HPAi
HPA042009
HPA042058

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

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BioGridi
131169, 2 interactors

Protein interaction database and analysis system

More...
IntActi
A6NNT2, 1 interactor

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

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ProteinModelPortali
A6NNT2

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
A6NNT2

Database of comparative protein structure models

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ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili74 – 101Sequence analysisAdd BLAST28
Coiled coili145 – 176Sequence analysisAdd BLAST32
Coiled coili757 – 810Sequence analysisAdd BLAST54

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi306 – 440Pro-richAdd BLAST135
Compositional biasi568 – 614Ala-richAdd BLAST47

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IJ37 Eukaryota
ENOG4112C1S LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000162979

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000202728

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG108740

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
A6NNT2

Identification of Orthologs from Complete Genome Data

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OMAi
KVTIHED

Database of Orthologous Groups

More...
OrthoDBi
EOG091G01GZ

Database for complete collections of gene phylogenies

More...
PhylomeDBi
A6NNT2

TreeFam database of animal gene trees

More...
TreeFami
TF339506

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR032013 DUF4795

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF16043 DUF4795, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A6NNT2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSFSLTFTEL ANIAIPQCGV LNFKALHLLL HGILEHIHMA ELKKVLSGDE
60 70 80 90 100
DFLQTSQVVI MPREGDAQPI LNPMKRLSNV FDHVVSRLDK LENQLALLQD
110 120 130 140 150
LPSTAQLLEA SQGTARPVQD LWHLIKLRKM VEGHDEVMAK SMQTLQDLLT
160 170 180 190 200
DLHALQVTIT ALRKEVDMLK NMLDKVHPER MDIFAEDFKI QNWKMVALQR
210 220 230 240 250
EVASLQNKFK TIPKTEDMVL WSGLHDAMFT SEIGSSPLDL WQSVEQLPEA
260 270 280 290 300
ALAQTTKYLE ATRAIQVSEP VQNPQLLQTV WHYEVPELLP EGSSAQAVSL
310 320 330 340 350
SRAQEPAQPP ALTPESAPGC TTEFAPGPAP GTEPVPGLEL GLELEPVPAL
360 370 380 390 400
GPVPGPSVTP GSLPAPWPVL GPVPAPGAQP PPLGDWPALP RRWPLPQGWP
410 420 430 440 450
RVGSWPLWDL GVLRPTQPQP SRAPPPATEF GSLWPRPLQP YQSRQGEALQ
460 470 480 490 500
LAAVQVKGEE NDVPSLRGLR ERARKDGAPK DRTRKDGVPK DRGGKDVDPK
510 520 530 540 550
DRAHKDDVPK DRGGKDVDPK DRAHKDDVPK DRGGKDGDPK DRVGKDGAPK
560 570 580 590 600
EAQPKAPQSA LHRLKTTAAI AAAAAAAYAA ATSSAAQAAK VAAKFVKDAP
610 620 630 640 650
ATKMAAIATD TAAAGPLGVF ADVLGAGPSR GATESQILGD DSEIYEILSP
660 670 680 690 700
SYSAASIGPD PALSQAMVAT KQAMSPEDKK RAVKYSMSHI AQIPVKHDSL
710 720 730 740 750
KEEFAQLSCN LNQRLSYLAN MGGPSSLGTT VDILQKKIGS LQKSRLKEEE
760 770 780 790 800
LERIWGNQIE MMKDRYITLD KAVENLQIRM DEFKTLQAQI KRLEMNKVNK
810 820 830 840 850
STMEEELREK ADRSALAGKA SRVDLETVAL ELNEMIQGIL FKVTIHEDSW
860 870 880 890 900
KKAMEELSKD VNTKLVHSDL DPLKKEMEEV WKIVRKLLIE GLRLDPDSAA
910 920 930 940 950
GFRRKLFKRV KCISCDRPVE MMTGPQLITI RKAHLLSRLR PASANSCEYL
960 970 980 990 1000
QRQQMREQQW LQLQDLGIQE DCQQDWGDGP QNATSLKCKS CNLLTLYPYG
1010 1020 1030 1040 1050
DPHVIDYDSA EVDILGVDGI LYKGRVNSQR GAQPLAVAKE LAAVKAPSPP
1060 1070 1080 1090 1100
SQSLYDRVHS SALFGAICPP LCPRSSACSA ASGPHLTMPA RPPSLPPLLL
1110 1120 1130 1140
LPPLIPSLRD PQQAPGSTRL SRAPHIESRV GRKPPEEPAN P
Length:1,141
Mass (Da):125,041
Last modified:October 19, 2011 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i2EC01FC5481CC306
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
AC023830 Genomic DNA No translation available.

The Consensus CDS (CCDS) project

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CCDSi
CCDS53986.1

NCBI Reference Sequences

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RefSeqi
NP_001138483.1, NM_001145011.1
XP_011520777.1, XM_011522475.2

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.684212

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000444310; ENSP00000415027; ENSG00000205832

Database of genes from NCBI RefSeq genomes

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GeneIDi
342346

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:342346

UCSC genome browser

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UCSCi
uc010uxn.3 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC023830 Genomic DNA No translation available.
CCDSiCCDS53986.1
RefSeqiNP_001138483.1, NM_001145011.1
XP_011520777.1, XM_011522475.2
UniGeneiHs.684212

3D structure databases

ProteinModelPortaliA6NNT2
SMRiA6NNT2
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi131169, 2 interactors
IntActiA6NNT2, 1 interactor

PTM databases

iPTMnetiA6NNT2
PhosphoSitePlusiA6NNT2

Polymorphism and mutation databases

BioMutaiC16orf96

Proteomic databases

PaxDbiA6NNT2
PRIDEiA6NNT2
ProteomicsDBi1635

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000444310; ENSP00000415027; ENSG00000205832
GeneIDi342346
KEGGihsa:342346
UCSCiuc010uxn.3 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
342346
EuPathDBiHostDB:ENSG00000205832.7

GeneCards: human genes, protein and diseases

More...
GeneCardsi
C16orf96
HGNCiHGNC:40031 C16orf96
HPAiHPA042009
HPA042058
neXtProtiNX_A6NNT2
OpenTargetsiENSG00000205832

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IJ37 Eukaryota
ENOG4112C1S LUCA
GeneTreeiENSGT00940000162979
HOGENOMiHOG000202728
HOVERGENiHBG108740
InParanoidiA6NNT2
OMAiKVTIHED
OrthoDBiEOG091G01GZ
PhylomeDBiA6NNT2
TreeFamiTF339506

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
342346

Protein Ontology

More...
PROi
PR:A6NNT2

Gene expression databases

BgeeiENSG00000205832 Expressed in 35 organ(s), highest expression level in testis

Family and domain databases

InterProiView protein in InterPro
IPR032013 DUF4795
PfamiView protein in Pfam
PF16043 DUF4795, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCP096_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A6NNT2
Secondary accession number(s): C9JH24
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 22, 2008
Last sequence update: October 19, 2011
Last modified: December 5, 2018
This is version 69 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 16
    Human chromosome 16: entries, gene names and cross-references to MIM
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