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Entry version 101 (08 May 2019)
Sequence version 4 (14 May 2014)
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Protein

Zinc finger protein 729

Gene

ZNF729

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri180 – 202C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri208 – 230C2H2-type 2; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri236 – 258C2H2-type 3; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri264 – 286C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri292 – 314C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri320 – 342C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri348 – 370C2H2-type 7; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri376 – 398C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri404 – 426C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri432 – 454C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri460 – 482C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri488 – 510C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri516 – 538C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri544 – 566C2H2-type 14PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri572 – 594C2H2-type 15PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri600 – 622C2H2-type 16PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri628 – 650C2H2-type 17PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri656 – 678C2H2-type 18PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri684 – 706C2H2-type 19PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri712 – 734C2H2-type 20PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri740 – 762C2H2-type 21PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri768 – 790C2H2-type 22PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri796 – 818C2H2-type 23PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri824 – 846C2H2-type 24PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri852 – 874C2H2-type 25PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri880 – 902C2H2-type 26PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri908 – 930C2H2-type 27PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri936 – 958C2H2-type 28PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri964 – 986C2H2-type 29PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri992 – 1014C2H2-type 30PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri1020 – 1042C2H2-type 31PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri1048 – 1070C2H2-type 32PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri1076 – 1098C2H2-type 33PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri1104 – 1126C2H2-type 34PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri1132 – 1154C2H2-type 35PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri1160 – 1182C2H2-type 36PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri1188 – 1210C2H2-type 37PROSITE-ProRule annotationAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-212436 Generic Transcription Pathway

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 729
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF729
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:32464 ZNF729

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_A6NN14

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000196350

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ZNF729

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003323141 – 1252Zinc finger protein 729Add BLAST1252

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
A6NN14

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
A6NN14

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
A6NN14

PRoteomics IDEntifications database

More...
PRIDEi
A6NN14

ProteomicsDB human proteome resource

More...
ProteomicsDBi
1578

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
A6NN14

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
A6NN14

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000196350 Expressed in 4 organ(s), highest expression level in right testis

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000469582

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
A6NN14

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini13 – 84KRABPROSITE-ProRule annotationAdd BLAST72

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri180 – 202C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri208 – 230C2H2-type 2; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri236 – 258C2H2-type 3; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri264 – 286C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri292 – 314C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri320 – 342C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri348 – 370C2H2-type 7; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri376 – 398C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri404 – 426C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri432 – 454C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri460 – 482C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri488 – 510C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri516 – 538C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri544 – 566C2H2-type 14PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri572 – 594C2H2-type 15PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri600 – 622C2H2-type 16PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri628 – 650C2H2-type 17PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri656 – 678C2H2-type 18PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri684 – 706C2H2-type 19PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri712 – 734C2H2-type 20PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri740 – 762C2H2-type 21PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri768 – 790C2H2-type 22PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri796 – 818C2H2-type 23PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri824 – 846C2H2-type 24PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri852 – 874C2H2-type 25PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri880 – 902C2H2-type 26PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri908 – 930C2H2-type 27PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri936 – 958C2H2-type 28PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri964 – 986C2H2-type 29PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri992 – 1014C2H2-type 30PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri1020 – 1042C2H2-type 31PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri1048 – 1070C2H2-type 32PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri1076 – 1098C2H2-type 33PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri1104 – 1126C2H2-type 34PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri1132 – 1154C2H2-type 35PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri1160 – 1182C2H2-type 36PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri1188 – 1210C2H2-type 37PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1721 Eukaryota
COG5048 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000163381

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000234617

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
A6NN14

KEGG Orthology (KO)

More...
KOi
K09228

Identification of Orthologs from Complete Genome Data

More...
OMAi
THRIRHT

Database of Orthologous Groups

More...
OrthoDBi
1318335at2759

TreeFam database of animal gene trees

More...
TreeFami
TF343410

Family and domain databases

Conserved Domains Database

More...
CDDi
cd07765 KRAB_A-box, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01352 KRAB, 1 hit
PF00096 zf-C2H2, 29 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00349 KRAB, 1 hit
SM00355 ZnF_C2H2, 37 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF109640 SSF109640, 1 hit
SSF57667 SSF57667, 20 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50805 KRAB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 34 hits
PS50157 ZINC_FINGER_C2H2_2, 37 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

A6NN14-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPGAPGSLEM GPLTFRDVTI EFSLEEWQCL DTVQQNLYRD VMLENYRNLV
60 70 80 90 100
FLGMAVFKPD LITCLKQGKE PWNMKRHEMV TKPPVMRSHF TQDLWPDQST
110 120 130 140 150
KDSFQEVILR TYARCGHKNL RLRKDCKSAN EGKMHKEGYN KLNQCRTATQ
160 170 180 190 200
RKIFQCNKHM KVFHKYSNRN KVRHTKKKTF KCIKCSKSFF MLSCLIRHKR
210 220 230 240 250
IHIRQNIYKC EERGKAFKSF STLTKHKIIH TEDKPYKYKK CGNAFKFSST
260 270 280 290 300
FTKHKRIHTG ETPFRCEECG KAFNQSSNLT DHKRIHTGEK TYKCEECGKA
310 320 330 340 350
FKGSSNFNAH KVIHTAEKPY KCEDCGKTFN HFSALRKHKI IHTGKKPYKR
360 370 380 390 400
EECGKAFSQS STLRKHEIIH TGEKPYKCEE CGKAFKWSSK LTVHKVVHTG
410 420 430 440 450
EKPYKCEECG KAFSQFSTLK KHKIIHTGKK PYKCEECGKA FNSSSTLMKH
460 470 480 490 500
KIIHTGEKPY KCEECGKAFR QSSHLTRHKA IHTGEKPYKC EECGKAFNHF
510 520 530 540 550
SDLRRHKIIH TGKKPYKCEE CGKAFSQSST LRNHQIIHTG EKPYKCEECG
560 570 580 590 600
KAFKWSSKLT VHKVIHTGEK PCKCEECGKA FKHFSALRKH KVIHTREKLY
610 620 630 640 650
KCEECGKAFN NSSILAKHKI IHTGKKPYKC EECGKAFRQS SHLTRHKAIH
660 670 680 690 700
TGEKPYKCEE CGKAFSHFSA LRRHKIIHTG KKPYKCEECG KAFSHFSALR
710 720 730 740 750
RHKIIHTGEK PYKCEECGKA FKWSSKLTVH KVIHTAEKPC KCEECGKSFK
760 770 780 790 800
HFSALRKHKV IHTREKLYKC EECVKAFNSF SALMKHKVIH TGEKPYKCEE
810 820 830 840 850
CGKAFKWSSK LTVHKVIHTG EKPCKCEECG KAFKHFSALR KHKVIHTGKK
860 870 880 890 900
PYKCEECGKA FSQSSSLRKH EIIHSGEKPY KCEECGKAFK WLSKLTVHKV
910 920 930 940 950
IHTAEKPCKC EECGKAFKHF SALRKHKIIH TGKKPYKCEE CGKAFNDSST
960 970 980 990 1000
LMKHKIIHTG KKPYKCAECG KAFKQSSHLT RHKAIHTGEK PYKCEECGKD
1010 1020 1030 1040 1050
FNNSSTLKKH KLIHTREKLY KCEECVKAFN NFSALMKHKI IHTGEKPYKC
1060 1070 1080 1090 1100
EECGKAFKWS SKLTEHKVIH TGEKPCKCEE CDKAFKHFSA LRKHKVIHTG
1110 1120 1130 1140 1150
KKPYQCDECG KAFNNSSTLT KHKIIHTGEK PYKCEECGKA FSQSSILTKH
1160 1170 1180 1190 1200
KIIHSVEKPY KCEECGKAFN QSSHLTRHKT IHTGEKPYKC EECGKAFIQC
1210 1220 1230 1240 1250
SYLIRHKTIH TREKPTNVKK VPKLLSNPHT LLDKTIHTGE KPYKCEECAK

AF
Length:1,252
Mass (Da):145,022
Last modified:May 14, 2014 - v4
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iDA92ED8A0114DE8F
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0G2JQ93A0A0G2JQ93_HUMAN
Zinc finger protein 729
ZNF729
10Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC011494 Genomic DNA No translation available.
AC073539 Genomic DNA No translation available.
BX956721 mRNA No translation available.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS59368.1

NCBI Reference Sequences

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RefSeqi
NP_001229609.1, NM_001242680.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000601693; ENSP00000469582; ENSG00000196350

Database of genes from NCBI RefSeq genomes

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GeneIDi
100287226

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
hsa:100287226

UCSC genome browser

More...
UCSCi
uc021urs.2 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC011494 Genomic DNA No translation available.
AC073539 Genomic DNA No translation available.
BX956721 mRNA No translation available.
CCDSiCCDS59368.1
RefSeqiNP_001229609.1, NM_001242680.1

3D structure databases

SMRiA6NN14
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000469582

PTM databases

iPTMnetiA6NN14
PhosphoSitePlusiA6NN14

Polymorphism and mutation databases

BioMutaiZNF729

Proteomic databases

EPDiA6NN14
jPOSTiA6NN14
PaxDbiA6NN14
PRIDEiA6NN14
ProteomicsDBi1578

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000601693; ENSP00000469582; ENSG00000196350
GeneIDi100287226
KEGGihsa:100287226
UCSCiuc021urs.2 human

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
100287226

GeneCards: human genes, protein and diseases

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GeneCardsi
ZNF729
HGNCiHGNC:32464 ZNF729
neXtProtiNX_A6NN14
OpenTargetsiENSG00000196350

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00940000163381
HOGENOMiHOG000234617
InParanoidiA6NN14
KOiK09228
OMAiTHRIRHT
OrthoDBi1318335at2759
TreeFamiTF343410

Enzyme and pathway databases

ReactomeiR-HSA-212436 Generic Transcription Pathway

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
100287226

Protein Ontology

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PROi
PR:A6NN14

Gene expression databases

BgeeiENSG00000196350 Expressed in 4 organ(s), highest expression level in right testis

Family and domain databases

CDDicd07765 KRAB_A-box, 1 hit
InterProiView protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF01352 KRAB, 1 hit
PF00096 zf-C2H2, 29 hits
SMARTiView protein in SMART
SM00349 KRAB, 1 hit
SM00355 ZnF_C2H2, 37 hits
SUPFAMiSSF109640 SSF109640, 1 hit
SSF57667 SSF57667, 20 hits
PROSITEiView protein in PROSITE
PS50805 KRAB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 34 hits
PS50157 ZINC_FINGER_C2H2_2, 37 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZN729_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A6NN14
Secondary accession number(s): M0QY45
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: May 14, 2014
Last modified: May 8, 2019
This is version 101 of the entry and version 4 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
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