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UniProtKB - A6NLC5 (CC070_HUMAN)
Protein
UPF0524 protein C3orf70
Gene
C3orf70
Organism
Homo sapiens (Human)
Status
Functioni
May play a role in neuronal and neurobehavioral development.
By similarityGO - Biological processi
- circadian behavior Source: UniProtKB
- nervous system development Source: UniProtKB
Keywordsi
Biological process | Neurogenesis |
Enzyme and pathway databases
PathwayCommonsi | A6NLC5 |
Names & Taxonomyi
Protein namesi | Recommended name: UPF0524 protein C3orf70 |
Gene namesi | Name:C3orf70 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:33731, C3orf70 |
neXtProti | NX_A6NLC5 |
VEuPathDBi | HostDB:ENSG00000187068 |
Pathology & Biotechi
Organism-specific databases
DisGeNETi | 285382 |
OpenTargetsi | ENSG00000187068 |
PharmGKBi | PA162379707 |
Miscellaneous databases
Pharosi | A6NLC5, Tdark |
Genetic variation databases
BioMutai | C3orf70 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000319976 | 1 – 250 | UPF0524 protein C3orf70Add BLAST | 250 |
Proteomic databases
jPOSTi | A6NLC5 |
MassIVEi | A6NLC5 |
MaxQBi | A6NLC5 |
PaxDbi | A6NLC5 |
PeptideAtlasi | A6NLC5 |
PRIDEi | A6NLC5 |
ProteomicsDBi | 1464 |
PTM databases
iPTMneti | A6NLC5 |
PhosphoSitePlusi | A6NLC5 |
Expressioni
Gene expression databases
Bgeei | ENSG00000187068, Expressed in forebrain and 203 other tissues |
Genevisiblei | A6NLC5, HS |
Organism-specific databases
HPAi | ENSG00000187068, Tissue enhanced (brain, smooth muscle) |
Interactioni
Protein-protein interaction databases
BioGRIDi | 130098, 1 interactor |
STRINGi | 9606.ENSP00000334974 |
Miscellaneous databases
RNActi | A6NLC5, protein |
Structurei
3D structure databases
AlphaFoldDBi | A6NLC5 |
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 201 – 250 | DisorderedSequence analysisAdd BLAST | 50 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 205 – 224 | Acidic residuesSequence analysisAdd BLAST | 20 | |
Compositional biasi | 227 – 250 | Polar residuesSequence analysisAdd BLAST | 24 |
Sequence similaritiesi
Belongs to the UPF0524 family.Curated
Phylogenomic databases
eggNOGi | ENOG502QQSJ, Eukaryota |
GeneTreei | ENSGT00390000006618 |
HOGENOMi | CLU_081879_0_0_1 |
InParanoidi | A6NLC5 |
OMAi | GAHKCPK |
OrthoDBi | 1244564at2759 |
PhylomeDBi | A6NLC5 |
TreeFami | TF328625 |
Family and domain databases
InterProi | View protein in InterPro IPR029670, UPF0524_fam |
PANTHERi | PTHR31785, PTHR31785, 1 hit |
Pfami | View protein in Pfam PF15823, UPF0524, 1 hit |
i Sequence
Sequence statusi: Complete.
A6NLC5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSAAASPASE RGWKSEKLDE AQALARSCAA RRPDFQPCDG LSICATHSHG
60 70 80 90 100
KCFKLHWCCH LGWCHCKYMY QPMTPVEQLP STEIPARPRE PTNTIQISVS
110 120 130 140 150
LTEHFLKFAS VFQPPLPPDS PRYCMISDLF IDNYQVKCIN GKMCYVQKQP
160 170 180 190 200
APHSHRMSPE EVSAHDALIS KESNTPKIDH CSSPSSSEDS GINAIGAHYV
210 220 230 240 250
ESCDEDTEEG AELSSEEDYS PESSWEPDEC TLLSPSQSDL EVIETIETTV
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC025573 Genomic DNA No translation available. CH471052 Genomic DNA Translation: EAW78232.1 BC137178 mRNA Translation: AAI37179.1 BC137179 mRNA Translation: AAI37180.1 BC150565 mRNA Translation: AAI50566.1 |
CCDSi | CCDS33900.1 |
RefSeqi | NP_001020437.1, NM_001025266.1 |
Genome annotation databases
Ensembli | ENST00000335012.3; ENSP00000334974.2; ENSG00000187068.3 |
GeneIDi | 285382 |
KEGGi | hsa:285382 |
MANE-Selecti | ENST00000335012.3; ENSP00000334974.2; NM_001025266.3; NP_001020437.1 |
UCSCi | uc003fpd.3, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC025573 Genomic DNA No translation available. CH471052 Genomic DNA Translation: EAW78232.1 BC137178 mRNA Translation: AAI37179.1 BC137179 mRNA Translation: AAI37180.1 BC150565 mRNA Translation: AAI50566.1 |
CCDSi | CCDS33900.1 |
RefSeqi | NP_001020437.1, NM_001025266.1 |
3D structure databases
AlphaFoldDBi | A6NLC5 |
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 130098, 1 interactor |
STRINGi | 9606.ENSP00000334974 |
PTM databases
iPTMneti | A6NLC5 |
PhosphoSitePlusi | A6NLC5 |
Genetic variation databases
BioMutai | C3orf70 |
Proteomic databases
jPOSTi | A6NLC5 |
MassIVEi | A6NLC5 |
MaxQBi | A6NLC5 |
PaxDbi | A6NLC5 |
PeptideAtlasi | A6NLC5 |
PRIDEi | A6NLC5 |
ProteomicsDBi | 1464 |
Protocols and materials databases
Antibodypediai | 52632, 39 antibodies from 11 providers |
DNASUi | 285382 |
Genome annotation databases
Ensembli | ENST00000335012.3; ENSP00000334974.2; ENSG00000187068.3 |
GeneIDi | 285382 |
KEGGi | hsa:285382 |
MANE-Selecti | ENST00000335012.3; ENSP00000334974.2; NM_001025266.3; NP_001020437.1 |
UCSCi | uc003fpd.3, human |
Organism-specific databases
CTDi | 285382 |
DisGeNETi | 285382 |
GeneCardsi | C3orf70 |
HGNCi | HGNC:33731, C3orf70 |
HPAi | ENSG00000187068, Tissue enhanced (brain, smooth muscle) |
neXtProti | NX_A6NLC5 |
OpenTargetsi | ENSG00000187068 |
PharmGKBi | PA162379707 |
VEuPathDBi | HostDB:ENSG00000187068 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | ENOG502QQSJ, Eukaryota |
GeneTreei | ENSGT00390000006618 |
HOGENOMi | CLU_081879_0_0_1 |
InParanoidi | A6NLC5 |
OMAi | GAHKCPK |
OrthoDBi | 1244564at2759 |
PhylomeDBi | A6NLC5 |
TreeFami | TF328625 |
Enzyme and pathway databases
PathwayCommonsi | A6NLC5 |
Miscellaneous databases
BioGRID-ORCSi | 285382, 15 hits in 1045 CRISPR screens |
ChiTaRSi | C3orf70, human |
GenomeRNAii | 285382 |
Pharosi | A6NLC5, Tdark |
PROi | PR:A6NLC5 |
RNActi | A6NLC5, protein |
Gene expression databases
Bgeei | ENSG00000187068, Expressed in forebrain and 203 other tissues |
Genevisiblei | A6NLC5, HS |
Family and domain databases
InterProi | View protein in InterPro IPR029670, UPF0524_fam |
PANTHERi | PTHR31785, PTHR31785, 1 hit |
Pfami | View protein in Pfam PF15823, UPF0524, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | CC070_HUMAN | |
Accessioni | A6NLC5Primary (citable) accession number: A6NLC5 Secondary accession number(s): B2RNY2, B9EH83 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 26, 2008 |
Last sequence update: | July 24, 2007 | |
Last modified: | May 25, 2022 | |
This is version 90 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Uncharacterized protein families (UPF)
List of uncharacterized protein family (UPF) entries - Human chromosome 3
Human chromosome 3: entries, gene names and cross-references to MIM - SIMILARITY comments
Index of protein domains and families