C3orf70

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: UPF0524 protein C3orf70
Gene namesⁱ	Name:C3orf70
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 3

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000187068.2
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:33731 C3orf70
neXtProtⁱ	NX_A6NLC5

Pathology & Biotechⁱ

Organism-specific databases

DisGeNET More...DisGeNETⁱ	285382
Open Targets More...OpenTargetsⁱ	ENSG00000187068
PharmGKBⁱ	PA162379707

Polymorphism and mutation databases

BioMutaⁱ	C3orf70

BioMutaⁱ

C3orf70

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000319976	1 – 250	UPF0524 protein C3orf70Add BLAST		250

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	A6NLC5
PaxDbⁱ	A6NLC5
PRIDEⁱ	A6NLC5
ProteomicsDBⁱ	1464

PTM databases

iPTMnetⁱ	A6NLC5
PhosphoSitePlusⁱ	A6NLC5

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000187068 Expressed in 187 organ(s), highest expression level in forebrain
CleanExⁱ	HS_C3orf70
Genevisibleⁱ	A6NLC5 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA041861

HPAⁱ

HPA041861

Interactionⁱ

Protein-protein interaction databases

BioGridⁱ	130098, 1 interactor

BioGridⁱ

130098, 1 interactor

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	A6NLC5
SMRⁱ	A6NLC5
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the UPF0524 family.Curated

Phylogenomic databases

eggNOGⁱ	ENOG410IGTG Eukaryota ENOG410XQHJ LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000006618
HOGENOMⁱ	HOG000043069
HOVERGENⁱ	HBG095343
InParanoidⁱ	A6NLC5
OMAⁱ	YMESCDE
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0OIG
PhylomeDBⁱ	A6NLC5
TreeFamⁱ	TF328625

Family and domain databases

InterProⁱ	View protein in InterPro IPR029670 UPF0524_fam
PANTHERⁱ	PTHR31785 PTHR31785, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF15823 UPF0524, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

A6NLC5-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MSAAASPASE RGWKSEKLDE AQALARSCAA RRPDFQPCDG LSICATHSHG 
        60         70         80         90        100
KCFKLHWCCH LGWCHCKYMY QPMTPVEQLP STEIPARPRE PTNTIQISVS 
       110        120        130        140        150
LTEHFLKFAS VFQPPLPPDS PRYCMISDLF IDNYQVKCIN GKMCYVQKQP 
       160        170        180        190        200
APHSHRMSPE EVSAHDALIS KESNTPKIDH CSSPSSSEDS GINAIGAHYV 
       210        220        230        240        250
ESCDEDTEEG AELSSEEDYS PESSWEPDEC TLLSPSQSDL EVIETIETTV

Length:250

Mass (Da):27,769

Last modified:July 24, 2007 - v1

Checksum:ⁱ5B2930FDE8905AC3

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC025573 Genomic DNA No translation available. CH471052 Genomic DNA Translation: EAW78232.1 BC137178 mRNA Translation: AAI37179.1 BC137179 mRNA Translation: AAI37180.1 BC150565 mRNA Translation: AAI50566.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS33900.1
NCBI Reference Sequences More...RefSeqⁱ	NP_001020437.1, NM_001025266.1
UniGeneⁱ	Hs.245793 Hs.380048

Genome annotation databases

Ensemblⁱ	ENST00000335012; ENSP00000334974; ENSG00000187068
GeneIDⁱ	285382
KEGGⁱ	hsa:285382
UCSC genome browser More...UCSCⁱ	uc003fpd.3 human

Protein	Similar proteins		Species	Score	Length	Source
A6NLC5	C3orf70 isoform 1		PANTR		250	UniRef100_A6NLC5

Protein	Similar proteins		Species	Score	Length	Source
A6NLC5	UPF0524 protein C3orf70 homolog		BOVIN		250	UniRef90_A6NLC5
UPF0524 protein C3orf70 homolog		MOUSE		248
C3orf70 isoform 1		PANTR		250
Chromosome 3 open reading frame 70		NOMLE		263
Uncharacterized protein		AOTNA		253
+84

Protein	Similar proteins		Species	Score	Length	Source
A6NLC5	UPF0524 protein C3orf70 homolog		BOVIN		250	UniRef50_A6NLC5
UPF0524 protein C3orf70 homolog		MOUSE		248
C3orf70 isoform 1		PANTR		250
Chromosome 3 open reading frame 70		NOMLE		263
Uncharacterized protein		AOTNA		253
+156

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC025573 Genomic DNA No translation available. CH471052 Genomic DNA Translation: EAW78232.1 BC137178 mRNA Translation: AAI37179.1 BC137179 mRNA Translation: AAI37180.1 BC150565 mRNA Translation: AAI50566.1
CCDSⁱ	CCDS33900.1
RefSeqⁱ	NP_001020437.1, NM_001025266.1
UniGeneⁱ	Hs.245793 Hs.380048

3D structure databases

ProteinModelPortalⁱ	A6NLC5
SMRⁱ	A6NLC5
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	130098, 1 interactor

BioGridⁱ

130098, 1 interactor

PTM databases

iPTMnetⁱ	A6NLC5
PhosphoSitePlusⁱ	A6NLC5

Polymorphism and mutation databases

BioMutaⁱ	C3orf70

BioMutaⁱ

C3orf70

Proteomic databases

MaxQBⁱ	A6NLC5
PaxDbⁱ	A6NLC5
PRIDEⁱ	A6NLC5
ProteomicsDBⁱ	1464

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000335012; ENSP00000334974; ENSG00000187068
GeneIDⁱ	285382
KEGGⁱ	hsa:285382
UCSCⁱ	uc003fpd.3 human

Organism-specific databases

CTDⁱ	285382
DisGeNETⁱ	285382
EuPathDBⁱ	HostDB:ENSG00000187068.2
GeneCardsⁱ	C3orf70
HGNCⁱ	HGNC:33731 C3orf70
HPAⁱ	HPA041861
neXtProtⁱ	NX_A6NLC5
OpenTargetsⁱ	ENSG00000187068
PharmGKBⁱ	PA162379707
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	ENOG410IGTG Eukaryota ENOG410XQHJ LUCA
GeneTreeⁱ	ENSGT00390000006618
HOGENOMⁱ	HOG000043069
HOVERGENⁱ	HBG095343
InParanoidⁱ	A6NLC5
OMAⁱ	YMESCDE
OrthoDBⁱ	EOG091G0OIG
PhylomeDBⁱ	A6NLC5
TreeFamⁱ	TF328625

Miscellaneous databases

ChiTaRSⁱ	C3orf70 human
GenomeRNAiⁱ	285382
Protein Ontology More...PROⁱ	PR:A6NLC5

Gene expression databases

Bgeeⁱ	ENSG00000187068 Expressed in 187 organ(s), highest expression level in forebrain
CleanExⁱ	HS_C3orf70
Genevisibleⁱ	A6NLC5 HS

Family and domain databases

InterProⁱ	View protein in InterPro IPR029670 UPF0524_fam
PANTHERⁱ	PTHR31785 PTHR31785, 1 hit
Pfamⁱ	View protein in Pfam PF15823 UPF0524, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	CC070_HUMAN
Accessionⁱ	A6NLC5Primary (citable) accession number: A6NLC5 Secondary accession number(s): B2RNY2, B9EH83
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	February 26, 2008
	Last sequence update:	July 24, 2007
	Last modified:	September 12, 2018
	This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
Human chromosome 3
Human chromosome 3: entries, gene names and cross-references to MIM
Uncharacterized protein families (UPF)
List of uncharacterized protein family (UPF) entries

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - A6NLC5 (CC070_HUMAN)

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UPF0524 protein C3orf70

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<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Documents

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Names & Taxonomyⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ