Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 111 (02 Dec 2020)
Sequence version 2 (11 Jan 2011)
Previous versions | rss
Add a publicationFeedback
Protein

Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 5

Gene

AGAP5

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Putative GTPase-activating protein.Curated

Miscellaneous

Encoded by one of the numerous copies of centaurin gamma-like genes clustered in the q11 region of chromosome 10.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri479 – 502C4-type; degeneratePROSITE-ProRule annotationAdd BLAST24

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionGTPase activation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
A6NIR3

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 5
Short name:
AGAP-5
Alternative name(s):
Centaurin-gamma-like family member 2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:AGAP5
Synonyms:CTGLF2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 10

Organism-specific databases

Eukaryotic Pathogen and Host Database Resources

More...
EuPathDBi
HostDB:ENSG00000172650.12

Human Gene Nomenclature Database

More...
HGNCi
HGNC:23467, AGAP5

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_A6NIR3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA164715123

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
A6NIR3, Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
AGAP5

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003492051 – 686Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 5Add BLAST686

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
A6NIR3

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
A6NIR3

MaxQB - The MaxQuant DataBase

More...
MaxQBi
A6NIR3

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
A6NIR3

PeptideAtlas

More...
PeptideAtlasi
A6NIR3

PRoteomics IDEntifications database

More...
PRIDEi
A6NIR3

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
1279

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
A6NIR3

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
A6NIR3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000172650, Expressed in body of pancreas and 112 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
A6NIR3, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
A6NIR3, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000172650, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
609497, 2 interactors

Protein interaction database and analysis system

More...
IntActi
A6NIR3, 2 interactors

Molecular INTeraction database

More...
MINTi
A6NIR3

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000363207

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
A6NIR3, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
A6NIR3

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini282 – 443PHPROSITE-ProRule annotationAdd BLAST162
Domaini464 – 584Arf-GAPPROSITE-ProRule annotationAdd BLAST121
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati623 – 652ANK 1Add BLAST30
Repeati656 – 685ANK 2Add BLAST30

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the centaurin gamma-like family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri479 – 502C4-type; degeneratePROSITE-ProRule annotationAdd BLAST24

Keywords - Domaini

ANK repeat, Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0705, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000163475

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
A6NIR3

Database of Orthologous Groups

More...
OrthoDBi
751525at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
A6NIR3

TreeFam database of animal gene trees

More...
TreeFami
TF317762

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.40.20, 1 hit
3.30.40.160, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002110, Ankyrin_rpt
IPR020683, Ankyrin_rpt-contain_dom
IPR036770, Ankyrin_rpt-contain_sf
IPR037278, ARFGAP/RecO
IPR001164, ArfGAP_dom
IPR038508, ArfGAP_dom_sf
IPR001849, PH_domain

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12796, Ank_2, 1 hit
PF01412, ArfGap, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00405, REVINTRACTNG

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00248, ANK, 2 hits
SM00105, ArfGap, 1 hit
SM00233, PH, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48403, SSF48403, 1 hit
SSF57863, SSF57863, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50297, ANK_REP_REGION, 1 hit
PS50088, ANK_REPEAT, 1 hit
PS50115, ARFGAP, 1 hit
PS50003, PH_DOMAIN, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

A6NIR3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGNILTCCVH PSVSLEFDQQ QGSVCPSESE IYEAGAGDRM AGAPMAAAVQ
60 70 80 90 100
PAEVTVEVGE DLHMHHIRDQ EMPEALEFSL SANPEASTIF QRNSQTDALE
110 120 130 140 150
FNPSANPEAS TIFQRNSQTD VVEIRRSNCT NHVSTERFSQ QYSSCSTIFL
160 170 180 190 200
DDSTASQHYL TMTIISVTLE IPHHITQRDA DRSLSIPDEQ LHSFAVSTVH
210 220 230 240 250
ITKNRNGGGS LNNYSSSIPS TPSTSQEDPQ FSVPPTANTP TPVCKRSMRW
260 270 280 290 300
SNLFTSEKGS HPDKERKAPE NHADTIGSGR AIPIKQGMLL KRSGKWLKTW
310 320 330 340 350
KKKYVTLCSN GVLTYYSSLG DYMKNIHKKE IDLRTSTIKV PGKWPSLATS
360 370 380 390 400
ACAPISSSKS NGLSKDMDTG LGDSICFSPS ISSTTSPKLN PPPSPHANKK
410 420 430 440 450
KHLKKKSTNN FMIVSATGQT WHFEATTYEE RDAWVQAIQS QILASLQSCE
460 470 480 490 500
SSKSKSQLTS QSEAMALQSI QNMRGNAHCV DYETQNPKWA SLNLGVLMCI
510 520 530 540 550
ECSGIHRSLG TRLSRVRSLE LDDWPVELRK VMSSIGNDLA NSIWEGSSQG
560 570 580 590 600
QTKPSVKSTR EEKERWIRSK YEEKLFLAPL PCTELSLGQH LLRATADEDL
610 620 630 640 650
QTAILLLAHG SREEVNETCG EGDGCTALHL ACRKGNVVLA QLLIWYGVDV
660 670 680
MARDAHGNTA LTYARQASSQ ECINVLLQYG CPDECV
Length:686
Mass (Da):75,492
Last modified:January 11, 2011 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC51D1E96C6179B24
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
J3KQL4J3KQL4_HUMAN
Arf-GAP with GTPase, ANK repeat and...
AGAP5
663Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0D9SFU9A0A0D9SFU9_HUMAN
Arf-GAP with GTPase, ANK repeat and...
AGAP5
686Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
U3KQ60U3KQ60_HUMAN
Arf-GAP with GTPase, ANK repeat and...
AGAP5
27Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti8C → R in BC127746 (PubMed:15489334).Curated1
Sequence conflicti365K → E in BC127746 (PubMed:15489334).Curated1
Sequence conflicti482Y → C in BC127746 (PubMed:15489334).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC073389 Genomic DNA No translation available.
AC022400 Genomic DNA No translation available.
BC127746 mRNA No translation available.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS44439.1

NCBI Reference Sequences

More...
RefSeqi
NP_001137472.1, NM_001144000.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000374094; ENSP00000363207; ENSG00000172650

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
729092

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:729092

UCSC genome browser

More...
UCSCi
uc009xri.4, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC073389 Genomic DNA No translation available.
AC022400 Genomic DNA No translation available.
BC127746 mRNA No translation available.
CCDSiCCDS44439.1
RefSeqiNP_001137472.1, NM_001144000.1

3D structure databases

SMRiA6NIR3
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi609497, 2 interactors
IntActiA6NIR3, 2 interactors
MINTiA6NIR3
STRINGi9606.ENSP00000363207

PTM databases

iPTMnetiA6NIR3
PhosphoSitePlusiA6NIR3

Polymorphism and mutation databases

BioMutaiAGAP5

Proteomic databases

jPOSTiA6NIR3
MassIVEiA6NIR3
MaxQBiA6NIR3
PaxDbiA6NIR3
PeptideAtlasiA6NIR3
PRIDEiA6NIR3
ProteomicsDBi1279

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
68077, 43 antibodies

Genome annotation databases

EnsembliENST00000374094; ENSP00000363207; ENSG00000172650
GeneIDi729092
KEGGihsa:729092
UCSCiuc009xri.4, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
729092
EuPathDBiHostDB:ENSG00000172650.12

GeneCards: human genes, protein and diseases

More...
GeneCardsi
AGAP5
HGNCiHGNC:23467, AGAP5
HPAiENSG00000172650, Low tissue specificity
neXtProtiNX_A6NIR3
PharmGKBiPA164715123

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG0705, Eukaryota
GeneTreeiENSGT00940000163475
InParanoidiA6NIR3
OrthoDBi751525at2759
PhylomeDBiA6NIR3
TreeFamiTF317762

Enzyme and pathway databases

PathwayCommonsiA6NIR3

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
729092, 299 hits in 807 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
729092
PharosiA6NIR3, Tdark

Protein Ontology

More...
PROi
PR:A6NIR3
RNActiA6NIR3, protein

Gene expression databases

BgeeiENSG00000172650, Expressed in body of pancreas and 112 other tissues
ExpressionAtlasiA6NIR3, baseline and differential
GenevisibleiA6NIR3, HS

Family and domain databases

Gene3Di1.25.40.20, 1 hit
3.30.40.160, 1 hit
InterProiView protein in InterPro
IPR002110, Ankyrin_rpt
IPR020683, Ankyrin_rpt-contain_dom
IPR036770, Ankyrin_rpt-contain_sf
IPR037278, ARFGAP/RecO
IPR001164, ArfGAP_dom
IPR038508, ArfGAP_dom_sf
IPR001849, PH_domain
PfamiView protein in Pfam
PF12796, Ank_2, 1 hit
PF01412, ArfGap, 1 hit
PRINTSiPR00405, REVINTRACTNG
SMARTiView protein in SMART
SM00248, ANK, 2 hits
SM00105, ArfGap, 1 hit
SM00233, PH, 1 hit
SUPFAMiSSF48403, SSF48403, 1 hit
SSF57863, SSF57863, 1 hit
PROSITEiView protein in PROSITE
PS50297, ANK_REP_REGION, 1 hit
PS50088, ANK_REPEAT, 1 hit
PS50115, ARFGAP, 1 hit
PS50003, PH_DOMAIN, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiAGAP5_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A6NIR3
Secondary accession number(s): A8MSN5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: January 11, 2011
Last modified: December 2, 2020
This is version 111 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 10
    Human chromosome 10: entries, gene names and cross-references to MIM
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again