UniProtKB - A6NIK2 (LR10B_HUMAN)
Protein
Leucine-rich repeat-containing protein 10B
Gene
LRRC10B
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Recommended name: Leucine-rich repeat-containing protein 10B |
Gene namesi | Name:LRRC10B |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:37215, LRRC10B |
neXtProti | NX_A6NIK2 |
VEuPathDBi | HostDB:ENSG00000204950.3 |
Pathology & Biotechi
Organism-specific databases
DisGeNETi | 390205 |
OpenTargetsi | ENSG00000204950 |
PharmGKBi | PA165543456 |
Miscellaneous databases
Pharosi | A6NIK2, Tdark |
Genetic variation databases
BioMutai | LRRC10B |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000346162 | 1 – 292 | Leucine-rich repeat-containing protein 10BAdd BLAST | 292 |
Proteomic databases
jPOSTi | A6NIK2 |
PaxDbi | A6NIK2 |
PeptideAtlasi | A6NIK2 |
PRIDEi | A6NIK2 |
ProteomicsDBi | 1273 |
PTM databases
iPTMneti | A6NIK2 |
PhosphoSitePlusi | A6NIK2 |
Expressioni
Gene expression databases
Bgeei | ENSG00000204950, Expressed in bronchial epithelial cell and 138 other tissues |
Genevisiblei | A6NIK2, HS |
Organism-specific databases
HPAi | ENSG00000204950, Group enriched (brain, fallopian tube, pituitary gland) |
Interactioni
Protein-protein interaction databases
STRINGi | 9606.ENSP00000367315 |
Miscellaneous databases
RNActi | A6NIK2, protein |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Repeati | 22 – 43 | LRR 1Add BLAST | 22 | |
Repeati | 45 – 66 | LRR 2Add BLAST | 22 | |
Repeati | 68 – 90 | LRR 3Add BLAST | 23 | |
Repeati | 91 – 112 | LRR 4Add BLAST | 22 | |
Repeati | 114 – 136 | LRR 5Add BLAST | 23 | |
Repeati | 137 – 158 | LRR 6Add BLAST | 22 | |
Repeati | 160 – 181 | LRR 7Add BLAST | 22 | |
Repeati | 183 – 204 | LRR 8Add BLAST | 22 | |
Repeati | 205 – 226 | LRR 9Add BLAST | 22 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 257 – 262 | Poly-Glu | 6 |
Keywords - Domaini
Leucine-rich repeat, RepeatPhylogenomic databases
eggNOGi | KOG0619, Eukaryota |
GeneTreei | ENSGT00940000155040 |
HOGENOMi | CLU_000288_18_15_1 |
InParanoidi | A6NIK2 |
OMAi | NELMEVP |
OrthoDBi | 1136570at2759 |
PhylomeDBi | A6NIK2 |
TreeFami | TF332853 |
Family and domain databases
Gene3Di | 3.80.10.10, 2 hits |
InterProi | View protein in InterPro IPR001611, Leu-rich_rpt IPR003591, Leu-rich_rpt_typical-subtyp IPR032675, LRR_dom_sf |
Pfami | View protein in Pfam PF13855, LRR_8, 1 hit |
SMARTi | View protein in SMART SM00369, LRR_TYP, 5 hits |
PROSITEi | View protein in PROSITE PS51450, LRR, 7 hits |
i Sequence
Sequence statusi: Complete.
A6NIK2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGIAESTPDE LPSDAEEQLR SGDQQLELSG RRLRRLPSAV CALSRLQKLY
60 70 80 90 100
VSGTGLRELP EEIEELRELR ILALDFNKLE RLPDGLCRLP RLTRLYLGGN
110 120 130 140 150
RLLALPADFA QLQSLRCLWI EGNFLRRFPR PLLRLVALQS LQMGDNRLRA
160 170 180 190 200
LPAELPRMTG LRGLWLYGNR FEEFPPALLR MGRLHILDLD RNRLGGFPDL
210 220 230 240 250
HPLRALRVFS YDHNPVTGPP RVADTVFLVG EGAVERMAER DEPTPRPPPR
260 270 280 290
RPARAFEDEE EEDLLIGGAG SRALGAPGGS FRALEAAPGL GT
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AP003108 Genomic DNA No translation available. |
CCDSi | CCDS44621.1 |
RefSeqi | NP_001138549.1, NM_001145077.1 |
Genome annotation databases
Ensembli | ENST00000378075; ENSP00000367315; ENSG00000204950 |
GeneIDi | 390205 |
KEGGi | hsa:390205 |
UCSCi | uc010rlk.2, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AP003108 Genomic DNA No translation available. |
CCDSi | CCDS44621.1 |
RefSeqi | NP_001138549.1, NM_001145077.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 9606.ENSP00000367315 |
PTM databases
iPTMneti | A6NIK2 |
PhosphoSitePlusi | A6NIK2 |
Genetic variation databases
BioMutai | LRRC10B |
Proteomic databases
jPOSTi | A6NIK2 |
PaxDbi | A6NIK2 |
PeptideAtlasi | A6NIK2 |
PRIDEi | A6NIK2 |
ProteomicsDBi | 1273 |
Protocols and materials databases
Antibodypediai | 67383, 16 antibodies |
Genome annotation databases
Ensembli | ENST00000378075; ENSP00000367315; ENSG00000204950 |
GeneIDi | 390205 |
KEGGi | hsa:390205 |
UCSCi | uc010rlk.2, human |
Organism-specific databases
CTDi | 390205 |
DisGeNETi | 390205 |
GeneCardsi | LRRC10B |
HGNCi | HGNC:37215, LRRC10B |
HPAi | ENSG00000204950, Group enriched (brain, fallopian tube, pituitary gland) |
neXtProti | NX_A6NIK2 |
OpenTargetsi | ENSG00000204950 |
PharmGKBi | PA165543456 |
VEuPathDBi | HostDB:ENSG00000204950.3 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG0619, Eukaryota |
GeneTreei | ENSGT00940000155040 |
HOGENOMi | CLU_000288_18_15_1 |
InParanoidi | A6NIK2 |
OMAi | NELMEVP |
OrthoDBi | 1136570at2759 |
PhylomeDBi | A6NIK2 |
TreeFami | TF332853 |
Enzyme and pathway databases
PathwayCommonsi | A6NIK2 |
Miscellaneous databases
BioGRID-ORCSi | 390205, 13 hits in 867 CRISPR screens |
GenomeRNAii | 390205 |
Pharosi | A6NIK2, Tdark |
PROi | PR:A6NIK2 |
RNActi | A6NIK2, protein |
Gene expression databases
Bgeei | ENSG00000204950, Expressed in bronchial epithelial cell and 138 other tissues |
Genevisiblei | A6NIK2, HS |
Family and domain databases
Gene3Di | 3.80.10.10, 2 hits |
InterProi | View protein in InterPro IPR001611, Leu-rich_rpt IPR003591, Leu-rich_rpt_typical-subtyp IPR032675, LRR_dom_sf |
Pfami | View protein in Pfam PF13855, LRR_8, 1 hit |
SMARTi | View protein in SMART SM00369, LRR_TYP, 5 hits |
PROSITEi | View protein in PROSITE PS51450, LRR, 7 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | LR10B_HUMAN | |
Accessioni | A6NIK2Primary (citable) accession number: A6NIK2 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | September 2, 2008 |
Last sequence update: | September 2, 2008 | |
Last modified: | February 10, 2021 | |
This is version 94 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Human chromosome 11
Human chromosome 11: entries, gene names and cross-references to MIM