Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Putative serine protease 29

Gene

PRSS29P

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Protein uncertaini

Functioni

Caution

Could be the product of a pseudogene.Curated

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei114Charge relay systemBy similarity1
Active sitei161Charge relay systemBy similarity1
Active sitei262Charge relay systemBy similarity1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protease, Serine protease

Names & Taxonomyi

Protein namesi
Recommended name:
Putative serine protease 29 (EC:3.4.21.-)
Alternative name(s):
Implantation serine proteinase 2-like protein
Short name:
ISP2-like protein
Gene namesi
Name:PRSS29P
Synonyms:ISP2
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Unplaced

Organism-specific databases

HGNCiHGNC:17542 PRSS29P
neXtProtiNX_A6NIE9

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_0000349227? – 313Putative serine protease 29
Signal peptidei1 – ?Sequence analysis

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi99 ↔ 115PROSITE-ProRule annotation
Glycosylationi143N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi193 ↔ 268PROSITE-ProRule annotation
Disulfide bondi226 ↔ 249PROSITE-ProRule annotation
Disulfide bondi258 ↔ 286PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PRIDEiA6NIE9
ProteomicsDBi1266
TopDownProteomicsiA6NIE9

Structurei

3D structure databases

ProteinModelPortaliA6NIE9
SMRiA6NIE9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini68 – 310Peptidase S1PROSITE-ProRule annotationAdd BLAST243

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi2 – 29Pro-richAdd BLAST28

Sequence similaritiesi

Belongs to the peptidase S1 family.PROSITE-ProRule annotation

Keywords - Domaini

Signal

Phylogenomic databases

HOGENOMiHOG000251820
HOVERGENiHBG013304
InParanoidiA6NIE9
PhylomeDBiA6NIE9

Family and domain databases

CDDicd00190 Tryp_SPc, 1 hit
InterProiView protein in InterPro
IPR009003 Peptidase_S1_PA
IPR001314 Peptidase_S1A
IPR001254 Trypsin_dom
IPR018114 TRYPSIN_HIS
IPR033116 TRYPSIN_SER
PfamiView protein in Pfam
PF00089 Trypsin, 1 hit
PRINTSiPR00722 CHYMOTRYPSIN
SMARTiView protein in SMART
SM00020 Tryp_SPc, 1 hit
SUPFAMiSSF50494 SSF50494, 1 hit
PROSITEiView protein in PROSITE
PS50240 TRYPSIN_DOM, 1 hit
PS00134 TRYPSIN_HIS, 1 hit
PS00135 TRYPSIN_SER, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

A6NIE9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPTTPDPGSE PPARTPRPPP LTPGLSPQPA LHALSPQLLL LLFLAVSSLG
60 70 80 90 100
SCSTGSPVPV PENDLVGIVG GHNAPPGKWP WQVSLRVYSY HWASWAHICG
110 120 130 140 150
GSLIHPQWVL TAAHCIFWKD TDPSIYRIHA GDVYLYGGRG LLNVSRIIVH
160 170 180 190 200
PNYVTAGLGA DVALLQLEPH DLSNVRTVKL SPVSLELTPK DQCWVTGWGA
210 220 230 240 250
IIRKESLPPP YRLQQASVQV LENAVCEQPY RNASGHTGDR QLILDDMLCA
260 270 280 290 300
GSEGRDSCYG DSGGPLVCRL RGSWRLVGVV SWGYGCTLRD FPGVYTHVQI
310
YVPWILQQVG ELP
Length:313
Mass (Da):34,063
Last modified:September 2, 2008 - v3
Checksum:i4DE6123C63C5F67C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC120498 Genomic DNA No translation available.
UniGeneiHs.738703

Similar proteinsi

Entry informationi

Entry nameiPRS29_HUMAN
AccessioniPrimary (citable) accession number: A6NIE9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: September 2, 2008
Last modified: June 20, 2018
This is version 63 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 16
    Human chromosome 16: entries, gene names and cross-references to MIM
  2. Peptidase families
    Classification of peptidase families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health