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Protein

Small integral membrane protein 9

Gene

SMIM9

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Names & Taxonomyi

Protein namesi
Recommended name:
Small integral membrane protein 9
Gene namesi
Name:SMIM9
Synonyms:CXorf68
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome X

Organism-specific databases

EuPathDBiHostDB:ENSG00000203870.5
HGNCiHGNC:41915 SMIM9
neXtProtiNX_A6NGZ8

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini27 – 73ExtracellularSequence analysisAdd BLAST47
Transmembranei74 – 94HelicalSequence analysisAdd BLAST21
Topological domaini95 – 99CytoplasmicSequence analysis5

Keywords - Cellular componenti

Cell membrane, Membrane

Pathology & Biotechi

Polymorphism and mutation databases

BioMutaiSMIM9

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 26Sequence analysisAdd BLAST26
ChainiPRO_000034824727 – 99Small integral membrane protein 9Add BLAST73

Proteomic databases

PaxDbiA6NGZ8
PRIDEiA6NGZ8
ProteomicsDBi1169

PTM databases

iPTMnetiA6NGZ8
PhosphoSitePlusiA6NGZ8

Expressioni

Gene expression databases

BgeeiENSG00000203870 Expressed in 62 organ(s), highest expression level in brain

Organism-specific databases

HPAiHPA060970

Structurei

3D structure databases

ProteinModelPortaliA6NGZ8
SMRiA6NGZ8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410JFBQ Eukaryota
ENOG4111B8Q LUCA
GeneTreeiENSGT00390000005685
HOGENOMiHOG000155728
InParanoidiA6NGZ8
OMAiNFRDYLW
OrthoDBiEOG091G15F1
PhylomeDBiA6NGZ8
TreeFamiTF354094

Family and domain databases

InterProiView protein in InterPro
IPR038853 Smim9
PANTHERiPTHR41687 PTHR41687, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

A6NGZ8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEPQKLLIIG FLLCSLTCLL LETVASSPLP LSALGIQEKT GSKPRSGGNH
60 70 80 90
RSWLNNFRDY LWQLIKSALP PAAIVAFLLT SALMGILCCF TILVVDPVH
Length:99
Mass (Da):10,777
Last modified:July 24, 2007 - v1
Checksum:iF88330841E92B319
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC109993 Genomic DNA No translation available.
CH471172 Genomic DNA Translation: EAW72652.1
CCDSiCCDS55546.1
RefSeqiNP_001156408.1, NM_001162936.1
UniGeneiHs.220762

Genome annotation databases

EnsembliENST00000369529; ENSP00000358542; ENSG00000203870
GeneIDi100132963
KEGGihsa:100132963
UCSCiuc065cja.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC109993 Genomic DNA No translation available.
CH471172 Genomic DNA Translation: EAW72652.1
CCDSiCCDS55546.1
RefSeqiNP_001156408.1, NM_001162936.1
UniGeneiHs.220762

3D structure databases

ProteinModelPortaliA6NGZ8
SMRiA6NGZ8
ModBaseiSearch...
MobiDBiSearch...

PTM databases

iPTMnetiA6NGZ8
PhosphoSitePlusiA6NGZ8

Polymorphism and mutation databases

BioMutaiSMIM9

Proteomic databases

PaxDbiA6NGZ8
PRIDEiA6NGZ8
ProteomicsDBi1169

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000369529; ENSP00000358542; ENSG00000203870
GeneIDi100132963
KEGGihsa:100132963
UCSCiuc065cja.1 human

Organism-specific databases

CTDi100132963
EuPathDBiHostDB:ENSG00000203870.5
GeneCardsiSMIM9
HGNCiHGNC:41915 SMIM9
HPAiHPA060970
neXtProtiNX_A6NGZ8
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410JFBQ Eukaryota
ENOG4111B8Q LUCA
GeneTreeiENSGT00390000005685
HOGENOMiHOG000155728
InParanoidiA6NGZ8
OMAiNFRDYLW
OrthoDBiEOG091G15F1
PhylomeDBiA6NGZ8
TreeFamiTF354094

Miscellaneous databases

GenomeRNAii100132963
PROiPR:A6NGZ8

Gene expression databases

BgeeiENSG00000203870 Expressed in 62 organ(s), highest expression level in brain

Family and domain databases

InterProiView protein in InterPro
IPR038853 Smim9
PANTHERiPTHR41687 PTHR41687, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiSMIM9_HUMAN
AccessioniPrimary (citable) accession number: A6NGZ8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: July 24, 2007
Last modified: September 12, 2018
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
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Main funding by: National Institutes of Health

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