UniProtKB - A6NGH8 (ANR61_HUMAN)
Protein
Ankyrin repeat domain-containing protein 61
Gene
ANKRD61
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Recommended name: Ankyrin repeat domain-containing protein 61 |
Gene namesi | Name:ANKRD61 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000157999.5 |
HGNCi | HGNC:22467, ANKRD61 |
neXtProti | NX_A6NGH8 |
Subcellular locationi
Nucleus
- nucleoplasm Source: HPA
Pathology & Biotechi
Organism-specific databases
DisGeNETi | 100310846 |
OpenTargetsi | ENSG00000157999 |
Miscellaneous databases
Pharosi | A6NGH8, Tdark |
Polymorphism and mutation databases
BioMutai | ANKRD61 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000328762 | 1 – 418 | Ankyrin repeat domain-containing protein 61Add BLAST | 418 |
Proteomic databases
PaxDbi | A6NGH8 |
PeptideAtlasi | A6NGH8 |
PRIDEi | A6NGH8 |
ProteomicsDBi | 1128 |
PTM databases
PhosphoSitePlusi | A6NGH8 |
Expressioni
Gene expression databases
Bgeei | ENSG00000157999, Expressed in testis and 108 other tissues |
Organism-specific databases
HPAi | ENSG00000157999, Group enriched (bone marrow, testis) |
Interactioni
Protein-protein interaction databases
STRINGi | 9606.ENSP00000386502 |
Miscellaneous databases
RNActi | A6NGH8, protein |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Repeati | 27 – 57 | ANK 1Add BLAST | 31 | |
Repeati | 75 – 104 | ANK 2Add BLAST | 30 | |
Repeati | 132 – 161 | ANK 3Add BLAST | 30 | |
Repeati | 167 – 196 | ANK 4Add BLAST | 30 | |
Repeati | 200 – 229 | ANK 5Add BLAST | 30 | |
Repeati | 234 – 273 | ANK 6Add BLAST | 40 | |
Repeati | 277 – 306 | ANK 7Add BLAST | 30 | |
Repeati | 310 – 343 | ANK 8Add BLAST | 34 |
Keywords - Domaini
ANK repeat, RepeatPhylogenomic databases
eggNOGi | KOG4177, Eukaryota |
GeneTreei | ENSGT00840000130004 |
HOGENOMi | CLU_054056_0_0_1 |
InParanoidi | A6NGH8 |
OMAi | YGTYPVL |
OrthoDBi | 780429at2759 |
PhylomeDBi | A6NGH8 |
TreeFami | TF352214 |
Family and domain databases
Gene3Di | 1.25.40.20, 3 hits |
InterProi | View protein in InterPro IPR002110, Ankyrin_rpt IPR020683, Ankyrin_rpt-contain_dom IPR036770, Ankyrin_rpt-contain_sf |
Pfami | View protein in Pfam PF12796, Ank_2, 1 hit |
PRINTSi | PR01415, ANKYRIN |
SMARTi | View protein in SMART SM00248, ANK, 5 hits |
SUPFAMi | SSF48403, SSF48403, 1 hit |
PROSITEi | View protein in PROSITE PS50297, ANK_REP_REGION, 1 hit PS50088, ANK_REPEAT, 5 hits |
i Sequence
Sequence statusi: Complete.
A6NGH8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGNITRKGSR DLVVDSAKSL EDGPSAALHS KLYEAIMRED CTTIEVLLRN
60 70 80 90 100
HPVNQPITIL PNSASNRLLL TQPTESIIPI HLAAKYHKAQ SLLCLLRHGA
110 120 130 140 150
DPEVRDTTGL TTLNLMLLHW PVTSTTWAKP GNRTHRILTD IQNSSITCLR
160 170 180 190 200
ILCAHGAQVN TQGEISNKRS PLHLAIAYGC YPVLSILTQN GADVNAINEA
210 220 230 240 250
SMTPLHMAAN MLNKEMMETL IAYGANVNCA VSSTGNTPLK LAVCTASSKA
260 270 280 290 300
GRLLGAGVSC IRLLLTHGAK VNAQDYKGQT AIHEACFGGR EAIINLLLEF
310 320 330 340 350
EANVNILTRN GESPIYMYLQ RSCNVRDTAL LARLLYHTYP LRMTNNQGIL
360 370 380 390 400
PAGIMLPEFR LLRDTLIKQS QKPLSLQGIC KRNIRNIYGE KYKQHLKQFL
410
PVTIWNSVYC CYDLAYTS
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC005995 Genomic DNA No translation available. |
CCDSi | CCDS64590.1 |
RefSeqi | NP_001258629.1, NM_001271700.1 |
Genome annotation databases
Ensembli | ENST00000409061; ENSP00000386502; ENSG00000157999 |
GeneIDi | 100310846 |
KEGGi | hsa:100310846 |
UCSCi | uc031swn.2, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC005995 Genomic DNA No translation available. |
CCDSi | CCDS64590.1 |
RefSeqi | NP_001258629.1, NM_001271700.1 |
3D structure databases
SMRi | A6NGH8 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 9606.ENSP00000386502 |
PTM databases
PhosphoSitePlusi | A6NGH8 |
Polymorphism and mutation databases
BioMutai | ANKRD61 |
Proteomic databases
PaxDbi | A6NGH8 |
PeptideAtlasi | A6NGH8 |
PRIDEi | A6NGH8 |
ProteomicsDBi | 1128 |
Protocols and materials databases
Antibodypediai | 49311, 55 antibodies |
Genome annotation databases
Ensembli | ENST00000409061; ENSP00000386502; ENSG00000157999 |
GeneIDi | 100310846 |
KEGGi | hsa:100310846 |
UCSCi | uc031swn.2, human |
Organism-specific databases
CTDi | 100310846 |
DisGeNETi | 100310846 |
EuPathDBi | HostDB:ENSG00000157999.5 |
GeneCardsi | ANKRD61 |
HGNCi | HGNC:22467, ANKRD61 |
HPAi | ENSG00000157999, Group enriched (bone marrow, testis) |
neXtProti | NX_A6NGH8 |
OpenTargetsi | ENSG00000157999 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG4177, Eukaryota |
GeneTreei | ENSGT00840000130004 |
HOGENOMi | CLU_054056_0_0_1 |
InParanoidi | A6NGH8 |
OMAi | YGTYPVL |
OrthoDBi | 780429at2759 |
PhylomeDBi | A6NGH8 |
TreeFami | TF352214 |
Enzyme and pathway databases
PathwayCommonsi | A6NGH8 |
Miscellaneous databases
BioGRID-ORCSi | 100310846, 4 hits in 808 CRISPR screens |
GenomeRNAii | 100310846 |
Pharosi | A6NGH8, Tdark |
PROi | PR:A6NGH8 |
RNActi | A6NGH8, protein |
Gene expression databases
Bgeei | ENSG00000157999, Expressed in testis and 108 other tissues |
Family and domain databases
Gene3Di | 1.25.40.20, 3 hits |
InterProi | View protein in InterPro IPR002110, Ankyrin_rpt IPR020683, Ankyrin_rpt-contain_dom IPR036770, Ankyrin_rpt-contain_sf |
Pfami | View protein in Pfam PF12796, Ank_2, 1 hit |
PRINTSi | PR01415, ANKYRIN |
SMARTi | View protein in SMART SM00248, ANK, 5 hits |
SUPFAMi | SSF48403, SSF48403, 1 hit |
PROSITEi | View protein in PROSITE PS50297, ANK_REP_REGION, 1 hit PS50088, ANK_REPEAT, 5 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | ANR61_HUMAN | |
Accessioni | A6NGH8Primary (citable) accession number: A6NGH8 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 8, 2008 |
Last sequence update: | July 22, 2008 | |
Last modified: | December 2, 2020 | |
This is version 91 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Human chromosome 7
Human chromosome 7: entries, gene names and cross-references to MIM