ANKRD61

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Ankyrin repeat domain-containing protein 61
Gene namesⁱ	Name:ANKRD61
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 7

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000157999.5
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:22467 ANKRD61
neXtProtⁱ	NX_A6NGH8

Pathology & Biotechⁱ

Organism-specific databases

Open Targets More...OpenTargetsⁱ	ENSG00000157999

OpenTargetsⁱ

ENSG00000157999

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000328762	1 – 418	Ankyrin repeat domain-containing protein 61Add BLAST		418

Proteomic databases

PaxDbⁱ	A6NGH8
PRIDEⁱ	A6NGH8
ProteomicsDBⁱ	1128

PTM databases

PhosphoSitePlusⁱ	A6NGH8

PhosphoSitePlusⁱ

A6NGH8

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000157999 Expressed in 86 organ(s), highest expression level in testis

Bgeeⁱ

ENSG00000157999 Expressed in 86 organ(s), highest expression level in testis

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA029511

HPAⁱ

HPA029511

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	9606.ENSP00000386502

STRINGⁱ

9606.ENSP00000386502

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	A6NGH8
SMRⁱ	A6NGH8
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Length
Repeatⁱ	27 – 57	ANK 1Add BLAST	31
Repeatⁱ	75 – 104	ANK 2Add BLAST	30
Repeatⁱ	132 – 161	ANK 3Add BLAST	30
Repeatⁱ	167 – 196	ANK 4Add BLAST	30
Repeatⁱ	200 – 229	ANK 5Add BLAST	30
Repeatⁱ	234 – 273	ANK 6Add BLAST	40
Repeatⁱ	277 – 306	ANK 7Add BLAST	30
Repeatⁱ	310 – 343	ANK 8Add BLAST	34

Keywords - Domainⁱ

ANK repeat, Repeat

Phylogenomic databases

eggNOGⁱ	KOG4177 Eukaryota COG0666 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00840000130004
HOGENOMⁱ	HOG000155553
InParanoidⁱ	A6NGH8
OMAⁱ	HEACFGG
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G07YZ
PhylomeDBⁱ	A6NGH8
TreeFamⁱ	TF352214

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00204 ANK, 3 hits
Gene3Dⁱ	1.25.40.20, 3 hits
InterProⁱ	View protein in InterPro IPR002110 Ankyrin_rpt IPR020683 Ankyrin_rpt-contain_dom IPR036770 Ankyrin_rpt-contain_sf
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF12796 Ank_2, 1 hit
PRINTSⁱ	PR01415 ANKYRIN
SMARTⁱ	View protein in SMART SM00248 ANK, 5 hits
SUPFAMⁱ	SSF48403 SSF48403, 1 hit
PROSITEⁱ	View protein in PROSITE PS50297 ANK_REP_REGION, 1 hit PS50088 ANK_REPEAT, 5 hits

Sequenceⁱ

Sequence statusⁱ: Complete.

A6NGH8-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MGNITRKGSR DLVVDSAKSL EDGPSAALHS KLYEAIMRED CTTIEVLLRN 
        60         70         80         90        100
HPVNQPITIL PNSASNRLLL TQPTESIIPI HLAAKYHKAQ SLLCLLRHGA 
       110        120        130        140        150
DPEVRDTTGL TTLNLMLLHW PVTSTTWAKP GNRTHRILTD IQNSSITCLR 
       160        170        180        190        200
ILCAHGAQVN TQGEISNKRS PLHLAIAYGC YPVLSILTQN GADVNAINEA 
       210        220        230        240        250
SMTPLHMAAN MLNKEMMETL IAYGANVNCA VSSTGNTPLK LAVCTASSKA 
       260        270        280        290        300
GRLLGAGVSC IRLLLTHGAK VNAQDYKGQT AIHEACFGGR EAIINLLLEF 
       310        320        330        340        350
EANVNILTRN GESPIYMYLQ RSCNVRDTAL LARLLYHTYP LRMTNNQGIL 
       360        370        380        390        400
PAGIMLPEFR LLRDTLIKQS QKPLSLQGIC KRNIRNIYGE KYKQHLKQFL 
       410 
PVTIWNSVYC CYDLAYTS

Length:418

Mass (Da):46,141

Last modified:July 22, 2008 - v2

Checksum:ⁱDD079DA78FFE4613

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC005995 Genomic DNA No translation available.
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS64590.1
NCBI Reference Sequences More...RefSeqⁱ	NP_001258629.1, NM_001271700.1
UniGeneⁱ	Hs.744468

Genome annotation databases

Ensemblⁱ	ENST00000409061; ENSP00000386502; ENSG00000157999
GeneIDⁱ	100310846
KEGGⁱ	hsa:100310846
UCSC genome browser More...UCSCⁱ	uc031swn.2 human

Protein	Similar proteins		Species	Score	Length	Source
A6NGH8	Ankyrin repeat domain 61		MACMU		438	UniRef90_A6NGH8
Ankyrin repeat domain 61		RHIBE		438
Ankyrin repeat domain 61		NOMLE		418
Ankyrin repeat domain 61		GORGO		418
ANKRD61 isoform 1		PANTR		418
+23

Protein	Similar proteins		Species	Score	Length	Source
A6NGH8	Ankyrin repeat domain-containing protein 61		BOVIN		424	UniRef50_A6NGH8
Ankyrin repeat domain 61		MACMU		438
Ankyrin repeat domain 61		RHIBE		438
Ankyrin repeat domain 61		NOMLE		418
ANKRD61 isoform 1		PONAB		418
+121

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC005995 Genomic DNA No translation available.
CCDSⁱ	CCDS64590.1
RefSeqⁱ	NP_001258629.1, NM_001271700.1
UniGeneⁱ	Hs.744468

3D structure databases

ProteinModelPortalⁱ	A6NGH8
SMRⁱ	A6NGH8
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	9606.ENSP00000386502

STRINGⁱ

9606.ENSP00000386502

PTM databases

PhosphoSitePlusⁱ	A6NGH8

PhosphoSitePlusⁱ

A6NGH8

Proteomic databases

PaxDbⁱ	A6NGH8
PRIDEⁱ	A6NGH8
ProteomicsDBⁱ	1128

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000409061; ENSP00000386502; ENSG00000157999
GeneIDⁱ	100310846
KEGGⁱ	hsa:100310846
UCSCⁱ	uc031swn.2 human

Organism-specific databases

CTDⁱ	100310846
EuPathDBⁱ	HostDB:ENSG00000157999.5
GeneCardsⁱ	ANKRD61
HGNCⁱ	HGNC:22467 ANKRD61
HPAⁱ	HPA029511
neXtProtⁱ	NX_A6NGH8
OpenTargetsⁱ	ENSG00000157999
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG4177 Eukaryota COG0666 LUCA
GeneTreeⁱ	ENSGT00840000130004
HOGENOMⁱ	HOG000155553
InParanoidⁱ	A6NGH8
OMAⁱ	HEACFGG
OrthoDBⁱ	EOG091G07YZ
PhylomeDBⁱ	A6NGH8
TreeFamⁱ	TF352214

Miscellaneous databases

GenomeRNAiⁱ	100310846
Protein Ontology More...PROⁱ	PR:A6NGH8

Gene expression databases

Bgeeⁱ	ENSG00000157999 Expressed in 86 organ(s), highest expression level in testis

Bgeeⁱ

ENSG00000157999 Expressed in 86 organ(s), highest expression level in testis

Family and domain databases

CDDⁱ	cd00204 ANK, 3 hits
Gene3Dⁱ	1.25.40.20, 3 hits
InterProⁱ	View protein in InterPro IPR002110 Ankyrin_rpt IPR020683 Ankyrin_rpt-contain_dom IPR036770 Ankyrin_rpt-contain_sf
Pfamⁱ	View protein in Pfam PF12796 Ank_2, 1 hit
PRINTSⁱ	PR01415 ANKYRIN
SMARTⁱ	View protein in SMART SM00248 ANK, 5 hits
SUPFAMⁱ	SSF48403 SSF48403, 1 hit
PROSITEⁱ	View protein in PROSITE PS50297 ANK_REP_REGION, 1 hit PS50088 ANK_REPEAT, 5 hits
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	ANR61_HUMAN
Accessionⁱ	A6NGH8Primary (citable) accession number: A6NGH8
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	April 8, 2008
	Last sequence update:	July 22, 2008
	Last modified:	September 12, 2018
	This is version 78 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

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UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - A6NGH8 (ANR61_HUMAN)

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Ankyrin repeat domain-containing protein 61

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<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

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Names & Taxonomyⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ